SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress

Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice

(2016) Qi Gong et al.   HEPATOLOGY

The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health

(2016) Mary Rinella et al.   HEPATOLOGY

Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort

(2016) Veronica Wendy Setiawan et al.   HEPATOLOGY

Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis

(2016) Matthew J. Armstrong et al.   JOURNAL OF HEPATOLOGY

Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study

(2016) Matthew James Armstrong et al.   LANCET

Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress

(2015) Hassan Melhem et al.   GUT

Adipocytokines and hepatic fibrosis

(2015) Neeraj K. Saxena et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

(2014) Darren C. Henstridge et al.   DIABETES

SIRT1 Mediates the Effect of GLP-1 Receptor Agonist Exenatide on Ameliorating Hepatic Steatosis

(2014) Fen Xu et al.   DIABETES

Benefits of exenatide on obesity and non-alcoholic fatty liver disease with elevated liver enzymes in patients with type 2 diabetes

(2014) Ning Shao et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

(2014) Darren C. Henstridge et al.   Molecular Metabolism

What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

(2013) Carmine Finelli   WORLD JOURNAL OF GASTROENTEROLOGY

Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1

(2013) R Ghemrawi et al.   Cell Death & Disease

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150

(2012) Tae Woo Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice

(2012) Jinmi Lee et al.   PLoS One

Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease

(2012) Alexandra K. Leamy et al.   PROGRESS IN LIPID RESEARCH

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

(2011) Julius Anckar et al.   Annual Review of Biochemistry

Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis

(2011) Jeffrey A. Handy et al.   BIOCHEMICAL JOURNAL

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy

(2011) Shvetank Sharma et al.   PLoS One

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

(2010) Kyle T. Pfaffenbach et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease

(2010) Christopher L. Gentile et al.   BIOFACTORS

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation

(2010) Fen Xu et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

(2010) Nitika Arora Gupta et al.   HEPATOLOGY

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Fatty liver and lipotoxicity

(2009) Michael Trauner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Extrapancreatic Effects of Glucagon-Like Peptide-1 and Related Peptides

(2009) Rania Abu-Hamdah et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

(2009) S. D. Westerheide et al.   SCIENCE

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism

ER Stress and Lipogenesis: A Slippery Slope toward Hepatic Steatosis

(2008) Sana Basseri et al.   DEVELOPMENTAL CELL

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

(2008) E. Bobrovnikova-Marjon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSP72 protects against obesity-induced insulin resistance

(2008) J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

(2008) Harmeet Malhi et al.   SEMINARS IN LIVER DISEASE