Vancomycin‐Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for Prevention

Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

(2020) Michael J Rybak et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Novel two chain fatty acid based-lipids for development of vancomycin pH-responsive liposomes against Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MRSA)

(2019) Sifiso S. Makhathini et al.   JOURNAL OF DRUG TARGETING

Delivery of novel vancomycin nanoplexes for combating methicillin resistant Staphylococcus aureus (MRSA) infections

(2019) Daniel Hassan et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats

(2019) Sevda Guzel et al.   DRUG AND CHEMICAL TOXICOLOGY

Comparative performance of urinary biomarkers for vancomycin induced kidney injury according to timeline of injury

(2019) Gwendolyn M. Pais et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Twenty-four hour pharmacokinetic relationships for intravenous vancomycin and novel urinary biomarkers of acute kidney injury in a rat model

(2019) Sean N Avedissian et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of fetal and maternal vancomycin-induced kidney injury during pregnancy in a rat model

(2019) Medha D. Joshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

60 Plus Years Later and We Are Still Trying to Learn How to Dose Vancomycin

(2019) Keith A Rodvold   CLINICAL INFECTIOUS DISEASES

The Emperor’s New Clothes: Prospective Observational Evaluation of the Association between Initial Vancomycin Exposure and Failure Rates among Adult Hospitalized Patients with MRSA Bloodstream Infections (PROVIDE)

(2019) Thomas P Lodise et al.   CLINICAL INFECTIOUS DISEASES

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America

(2019) Joshua P. Metlay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chitosan sponges as a sustained release carrier system for the prophylaxis of orthopedic implant-associated infections

(2019) Vaishali Pawar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Therapeutic efficacy of zingerone against vancomycin-induced oxidative stress, inflammation, apoptosis and aquaporin 1 permeability in rat kidney

(2018) Fatih Mehmet Kandemir et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Mice

(2018) Haohao Shi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update

(2018) Randy A. Taplitz et al.   JOURNAL OF CLINICAL ONCOLOGY

Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci

(2018) Dongliang Guan et al.   JOURNAL OF MEDICINAL CHEMISTRY

JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats

(2018) Shijie Wen et al.   TOXICOLOGY LETTERS

Biopsy-proven vancomycin-induced acute kidney injury: a case report and literature review

(2018) Anri Sawada et al.   BMC Nephrology

Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats

(2018) Zuhal Uckun et al.   DRUG AND CHEMICAL TOXICOLOGY

Estimated Costs of Pivotal Trials for Novel Therapeutic Agents Approved by the US Food and Drug Administration, 2015-2016

(2018) Thomas J. Moore et al.   JAMA Internal Medicine

Atg7 mediates renal tubular cell apoptosis in vancomycin nephrotoxicity through activation of PKC-δ

(2018) Xuan Xu et al.   FASEB JOURNAL

Parenterally administered vancomycin in 29 dogs and 7 cats (2003-2017)

(2018) Ian M. DeStefano et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Synergetic effect of vancomycin loaded silver nanoparticles for enhanced antibacterial activity

(2018) Amritpal Kaur et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Vancomycin induces reactive oxygen species-dependent apoptosis via mitochondrial cardiolipin peroxidation in renal tubular epithelial cells

(2017) Yuya Sakamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Vancomycin in the Kidney—A Novel Cast Nephropathy

(2017) M. Barry Stokes   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity

(2017) Yoshihisa Hori et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Vancomycin-Associated Cast Nephropathy

(2017) Yosu Luque et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Uromodulin: from physiology to rare and complex kidney disorders

(2017) Olivier Devuyst et al.   Nature Reviews Nephrology

Cilastatin attenuates vancomycin-induced nephrotoxicity via P-glycoprotein

(2017) Dai sig Im et al.   TOXICOLOGY LETTERS

MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

(2017) Juan Wang et al.   Cell Death & Disease

Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats

(2016) Nathaniel J. Rhodes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of pycnogenol and spirulina on vancomycin-induced renal cortical oxidative stress, apoptosis, and autophagy in adult male albino rat

(2016) Naglaa A. Bayomy et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

(2016) Andre C. Kalil et al.   CLINICAL INFECTIOUS DISEASES

Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation

(2016) Kathleen H. Wood et al.   Frontiers in Genetics

Review of vancomycin-induced renal toxicity: an update

(2016) Oluwatoyin Bamgbola   Therapeutic Advances in Endocrinology and Metabolism

p53 activates miR-192-5p to mediate vancomycin induced AKI

(2016) Jinwen Chen et al.   Scientific Reports

Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity

(2015) Blanca Humanes et al.   Biomed Research International

Liposomes for systematic delivery of vancomycin hydrochloride to decrease nephrotoxicity: Characterization and evaluation

(2015) Junli Liu et al.   Asian Journal of Pharmaceutical Sciences

Methicillin-Resistant Staphylococcus aureus Therapy: Past, Present, and Future

(2013) K. A. Rodvold et al.   CLINICAL INFECTIOUS DISEASES

Impact of vancomycin treatment duration and dose on kidney injury

(2013) Kirsten Bosch et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Difference in nephrotoxicity of vancomycin administered once daily and twice daily in rats

(2013) Hiroki Konishi et al.   JOURNAL OF CHEMOTHERAPY

The importance of vancomycin in drug rash with eosinophilia and systemic symptoms (dress) syndrome

(2012) Kimberly G. Blumenthal et al.   ALLERGY AND ASTHMA PROCEEDINGS

Immunocytochemistry for Vancomycin Using a Monoclonal Antibody That Reveals Accumulation of the Drug in Rat Kidney and Liver

(2012) Kunio Fujiwara et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prevention of vancomycin induced nephrotoxicity: a review of preclinical data

(2012) Sepideh Elyasi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Mitochondrial superoxide production contributes to vancomycin-induced renal tubular cell apoptosis

(2012) Yohei Arimura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats

(2012) F Basarslan et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Liposomal encapsulation of vancomycin improves killing of methicillin-resistant Staphylococcus aureus in a murine infection model

(2012) L. Sande et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

Biopsy-Proven Acute Tubular Necrosis Associated with Vancomycin in an Adult Patient

(2012) Cary Belen et al.   RENAL FAILURE

Evaluation of Novel Acute Urinary Rat Kidney Toxicity Biomarker for Subacute Toxicity Studies in Preclinical Trials

(2012) Tobias Christian Fuchs et al.   TOXICOLOGIC PATHOLOGY

PEGylated Liposome Encapsulation Increases the Lung Tissue Concentration of Vancomycin

(2011) Krishna Muppidi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Vancomycin AUC24/MIC Ratio in Patients with Complicated Bacteremia and Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus and Its Association with Attributable Mortality during Hospitalization

(2011) Jack Brown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biopsy-proven vancomycin-associated interstitial nephritis and acute tubular necrosis

(2011) Naing Lin Htike et al.   Clinical and Experimental Nephrology

Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America

(2011) Alison G. Freifeld et al.   CLINICAL INFECTIOUS DISEASES

Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children

(2011) Catherine Liu et al.   CLINICAL INFECTIOUS DISEASES

Imperfect Gold Standards for Kidney Injury Biomarker Evaluation

(2011) S. S. Waikar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Internalization ofStaphylococcus aureusin Lymphocytes Induces Oxidative Stress and DNA Fragmentation: Possible Ameliorative Role of Nanoconjugated Vancomycin

(2011) Subhankari Prasad Chakraborty et al.   Oxidative Medicine and Cellular Longevity

Protective role of curcumin in nephrotoxic oxidative damage induced by vancomycin in rats

(2010) Mohamed H.S. Ahmida   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

(2010) Vishal S Vaidya et al.   NATURE BIOTECHNOLOGY

Diagnosis and Management of Complicated Intra-Abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America

(2010) Joseph S. Solomkin et al.   Surgical Infections

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health‐System Pharmacists, and the Society of Infectious Diseases Pharmacists

(2009) Michael J. Rybak et al.   CLINICAL INFECTIOUS DISEASES

Relationship between Initial Vancomycin Concentration‐Time Profile and Nephrotoxicity among Hospitalized Patients

(2009) Thomas P. Lodise et al.   CLINICAL INFECTIOUS DISEASES

Nephrotoxicity of continuous versus intermittent infusion of vancomycin in outpatient parenteral antimicrobial therapy

(2009) Paul R. Ingram et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Creatinine Kinetics and the Definition of Acute Kidney Injury

(2009) S. S. Waikar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Creatinine as the gold standard for kidney injury biomarker studies?

(2009) S. S. Waikar et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of the poly(ADP-ribose)polymerase activity in vancomycin-induced renal injury

(2009) Selvinaz Dalaklioglu et al.   TOXICOLOGY LETTERS

Larger Vancomycin Doses (at Least Four Grams per Day) Are Associated with an Increased Incidence of Nephrotoxicity

(2008) T. P. Lodise et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Gene Expression Analysis Reveals New Possible Mechanisms of Vancomycin-Induced Nephrotoxicity and Identifies Gene Markers Candidates

(2008) Christine Dieterich et al.   TOXICOLOGICAL SCIENCES