Interaction between Salt-inducible Kinase 2 (SIK2) and p97/Valosin-containing Protein (VCP) Regulates Endoplasmic Reticulum (ER)-associated Protein Degradation in Mammalian Cells

Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy

(2013) Fu-Chia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expanding into new markets – VCP/p97 in endocytosis and autophagy

(2012) Monika Bug et al.   JOURNAL OF STRUCTURAL BIOLOGY

ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK

(2012) Arvin B. Tam et al.   PLoS One

Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways

(2011) Catherine Dargemont et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Salt-Inducible Kinase Is Involved in the Regulation of Corticotropin-Releasing Hormone Transcription in Hypothalamic Neurons in Rats

(2011) Ying Liu et al.   ENDOCRINOLOGY

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

(2011) Youngah Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genome-wide Screen Identifies p97 as an Essential Regulator of DNA Damage-Dependent CDT1 Destruction

(2011) Malavika Raman et al.   MOLECULAR CELL

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

(2011) Mayura Meerang et al.   NATURE CELL BIOLOGY

SIK2 Is a Key Regulator for Neuronal Survival after Ischemia via TORC1-CREB

(2011) Tsutomu Sasaki et al.   NEURON

p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system

(2010) Jeong-Sun Ju et al.   Autophagy

SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer

(2010) Ahmed Ashour Ahmed et al.   CANCER CELL

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

(2010) Youngah Jo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

(2010) Julien Bricambert et al.   JOURNAL OF CLINICAL INVESTIGATION

The complexities of p97 function in health and disease

(2010) Eli Chapman et al.   Molecular BioSystems

Downregulation of SIK2 expression promotes the melanogenic program in mice

(2010) Nanao Horike et al.   Pigment Cell & Melanoma Research

Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1α and UCP-1 gene expression in brown adipocytes

(2009) Masaaki Muraoka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

(2009) Jeong-Sun Ju et al.   JOURNAL OF CELL BIOLOGY

The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

(2008) Kunio Nakatsukasa et al.   TRAFFIC