Chlorpyrifos triggers epithelioma papulosum cyprini cell pyroptosis via miR-124-3p/CAPN1 axis

Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis

(2021) Yuan Jiang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The protective effects of Ziziphora tenuior L. against chlorpyrifos induced toxicity: Involvement of inflammatory and cell death signaling pathways

(2021) Fatemeh Kianpour et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chlorpyrifos pesticide promotes oxidative stress and increases inflammatory states in BV-2 microglial cells: A role in neuroinflammation

(2021) Grazielle Castagna Cezimbra Weis et al.   CHEMOSPHERE

Hydrogen sulfide exposure induces pyroptosis in the trachea of broilers via the regulatory effect of circRNA-17828/miR-6631-5p/DUSP6 crosstalk on ROS production

(2021) Nuan Song et al.   JOURNAL OF HAZARDOUS MATERIALS

Carnosic acid alleviates chlorpyrifos-induced oxidative stress and inflammation in mice cerebral and ocular tissues

(2020) Abdullah A. AlKahtane et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The role of Drp1 in mitophagy and cell death in the heart

(2020) Mingming Tong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy

(2020) Cheng Zeng et al.   Redox Biology

The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia

(2020) Mahmoud A.O. Dawood et al.   FISH & SHELLFISH IMMUNOLOGY

The regulation of the ZBP1‐NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis)

(2020) Min Zheng et al.   IMMUNOLOGICAL REVIEWS

Glutathione in Chlorpyrifos-and Chlorpyrifos-Oxon-Induced Toxicity: a Comparative Study Focused on Non-cholinergic Toxicity in HT22 Cells

(2020) Aline Aita Naime et al.   NEUROTOXICITY RESEARCH

Ecotoxicity of chlorpyrifos to aquatic organisms: A review

(2020) Xiao Huang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cadmium and molybdenum co-induce pyroptosis via ROS/PTEN/PI3K/AKT axis in duck renal tubular epithelial cells

(2020) Caiying Zhang et al.   ENVIRONMENTAL POLLUTION

Toxicity of polystyrene microplastics on juvenile Oncorhynchus mykiss (rainbow trout) after individual and combined exposure with chlorpyrifos‎

(2020) Samaneh Karbalaei et al.   JOURNAL OF HAZARDOUS MATERIALS

Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiota

(2019) Yiran Liang et al.   Microbiome

Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity by miR-181/SIRT1/PGC-1α/Nrf2 signaling pathway in human neuroblastoma SH-SY5Y cells: Implication for association between chlorpyrifos and Parkinson's

(2019) Meng-Wen Zhao et al.   ENVIRONMENTAL TOXICOLOGY

Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion

(2019) Ting Cao et al.   BASIC RESEARCH IN CARDIOLOGY

Chlorpyrifos induced oxidative stress to promote apoptosis and autophagy through the regulation of miR-19a-AMPK axis in common carp

(2019) Qiaojian Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Calpain silencing alleviates myocardial ischemia-reperfusion injury through the NLRP3/ASC/Caspase-1 axis in mice

(2019) Rong-Chuan Yue et al.   LIFE SCIENCES

STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3

(2019) Ning Li et al.   Redox Biology

Bio-sensing of organophosphorus pesticides: A review

(2019) C.S. Pundir et al.   BIOSENSORS & BIOELECTRONICS

MCU Up‐regulation contributes to myocardial ischemia‐reperfusion Injury through calpain/OPA‐1–mediated mitochondrial fusion/mitophagy Inhibition

(2019) Lichun Guan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of miR-731 and miR-2188-3p in mediating chlorpyrifos induced head kidney injury in common carp via targeting TLR and apoptosis pathways

(2019) Qi Liu et al.   AQUATIC TOXICOLOGY

Red beetroot extract mitigates chlorpyrifos-induced reprotoxicity associated with oxidative stress, inflammation, and apoptosis in rats

(2019) Gadah Albasher et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

miR-124 and Parkinson’s disease: A biomarker with therapeutic potential

(2019) Efthalia Angelopoulou et al.   PHARMACOLOGICAL RESEARCH

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

(2018) Xianxian Wu et al.   Cell Death & Disease

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

(2018) Yachun Han et al.   Redox Biology

Redox-regulation of calpains: consequences on vascular function

(2018) Voahanginirina Randriamboavonjy et al.   ANTIOXIDANTS & REDOX SIGNALING

A Membrane Potential- and Calpain-Dependent Reversal of Caspase-1 Inhibition Regulates Canonical NLRP3 Inflammasome

(2018) Yifei Zhang et al.   Cell Reports

Role of Post-Transcriptional Control of Calpain by miR-124-3p in the Development of Alzheimer’s Disease

(2018) Yajun Zhou et al.   JOURNAL OF ALZHEIMERS DISEASE

Histopathological effects, responses of oxidative stress, inflammation, apoptosis biomarkers and alteration of gene expressions related to apoptosis, oxidative stress, and reproductive system in chlorpyrifos-exposed common carp ( Cyprinus carpio L.)

(2017) Serdar Altun et al.   ENVIRONMENTAL POLLUTION

Chlorpyrifos exposure in common carp (Cyprinus carpio L.) leads to oxidative stress and immune responses

(2017) Ziwei Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

The single and joint toxicity effects of chlorpyrifos and beta-cypermethrin in zebrafish ( Danio rerio ) early life stages

(2017) Jiayu Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

miR-124 suppresses proliferation and invasion of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway by targeting Capn4

(2017) Haili Hu et al.   OncoTargets and Therapy

Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells

(2017) Shigeru Yamada et al.   Scientific Reports

Calpastatin overexpression reduces oxidative stress-induced mitochondrial impairment and cell death in human neuroblastoma SH-SY5Y cells by decreasing calpain and calcineurin activation, induction of mitochondrial fission and destruction of mitochondrial fusion

(2016) Kulvadee Tangmansakulchai et al.   MITOCHONDRION

PD150606 protects against ischemia/reperfusion injury by preventing μ-calpain-induced mitochondrial apoptosis

(2015) Tao Luo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

(2015) Coen H. Wiegman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

miR-124 suppresses the migration and invasion of glioma cells in vitro via Capn4

(2015) JIA-JUN CAI et al.   ONCOLOGY REPORTS

Chlorpyrifos induces NLRP3 inflammasome and pyroptosis/apoptosis via mitochondrial oxidative stress in human keratinocyte HaCaT cells

(2015) Yoonjeong Jang et al.   TOXICOLOGY

Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes

(2014) Bainian Chen et al.   Cardiovascular Diabetology

Nitric oxide-based protein modification: formation and site-specificity of protein S-nitrosylation: Could protein S-nitrosylation be the unifying oxidative modification to explain the cellular signaling activity of superoxide and hydrogen peroxide?

(2014) Marie-Veronique Clement   FREE RADICAL BIOLOGY AND MEDICINE

Downregulation of miR-124 in MPTP-treated mouse model of Parkinson’s disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins

(2014) N. Kanagaraj et al.   NEUROSCIENCE

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

(2013) Laura D. Osellame et al.   Cell Metabolism

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Evaluation of DNA damage and cytotoxicity induced by three commonly used organophosphate pesticides individually and in mixture, in rat tissues

(2011) Anupama Ojha et al.   ENVIRONMENTAL TOXICOLOGY

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

The Nlrp3 inflammasome: contributions to intestinal homeostasis

(2011) Md. Hasan Zaki et al.   TRENDS IN IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Mitochondrial Inner Membrane GTPase, Optic Atrophy 1 (Opa1), Restores Mitochondrial Morphology and Promotes Neuronal Survival following Excitotoxicity

(2010) Arezu Jahani-Asl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4

(2010) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY