Structural basis for the final steps of human 40S ribosome maturation

USP16 counteracts mono-ubiquitination of RPS27a and promotes maturation of the 40S ribosomal subunit

(2020) Christian Montellese et al.   eLife

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

(2020) Artem Babaian et al.   Cell Reports

Interactions and activities of factors involved in the late stages of human 18S rRNA maturation

(2019) Katherine Elizabeth Sloan et al.   RNA Biology

Uncovering the assembly pathway of human ribosomes and its emerging links to disease

(2019) Katherine E Bohnsack et al.   EMBO JOURNAL

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

(2019) Nhan van Tran et al.   NUCLEIC ACIDS RESEARCH

Structure of a eukaryotic cytoplasmic pre‐40S ribosomal subunit

(2018) Alain Scaiola et al.   EMBO JOURNAL

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number

(2018) Katherine I. Farley-Barnes et al.   Cell Reports

Visualizing late states of human 40S ribosomal subunit maturation

(2018) Michael Ameismeier et al.   NATURE

Landscape of the complete RNA chemical modifications in the human 80S ribosome

(2018) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

Maturation of pre‐40S particles in yeast and humans

(2018) Emilie Cerezo et al.   Wiley Interdisciplinary Reviews-RNA

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome

(2017) Thierry Bertomeu et al.   MOLECULAR AND CELLULAR BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

(2017) André Heuer et al.   eLife

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans

(2016) Britta Meyer et al.   NUCLEIC ACIDS RESEARCH

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells

(2015) Lukas Badertscher et al.   Cell Reports

Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions

(2015) Alan Brown et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CK1  and CK1  are components of human 40S subunit precursors required for cytoplasmic 40S maturation

(2014) I. Zemp et al.   JOURNAL OF CELL SCIENCE

Rio1 mediates ATP-dependent final maturation of 40S ribosomal subunits

(2014) Tomasz W. Turowski et al.   NUCLEIC ACIDS RESEARCH

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution

(2014) Ralph D. Hector et al.   NUCLEIC ACIDS RESEARCH

Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes

(2014) Sébastien Ferreira-Cerca et al.   NUCLEIC ACIDS RESEARCH

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

A Translation-Like Cycle Is a Quality Control Checkpoint for Maturing 40S Ribosome Subunits

(2012) Bethany S. Strunk et al.   CELL

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

(2012) Simon Lebaron et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits

(2011) Barbara Widmann et al.   MOLECULAR BIOLOGY OF THE CELL

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

(2010) Marie-Françoise O’Donohue et al.   JOURNAL OF CELL BIOLOGY

Tandem affinity purification combined with inducible shRNA expression as a tool to study the maturation of macromolecular assemblies

(2010) E. Wyler et al.   RNA

RNA Helicase Prp43 and Its Co-factor Pfa1 Promote 20 to 18 S rRNA Processing Catalyzed by the Endonuclease Nob1

(2009) Brigitte Pertschy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

(2009) Ivo Zemp et al.   JOURNAL OF CELL BIOLOGY

Nob1 binds the single-stranded cleavage site D at the 3'-end of 18S rRNA with its PIN domain

(2009) A. C. Lamanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA