Deciphering the role of damage-associated molecular patterns and inflammatory responses in acute lung injury

MicroRNAs: Important Regulatory Molecules in Acute Lung Injury/Acute Respiratory Distress Syndrome

(2022) Qianying Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Release mechanisms of major DAMPs

(2021) Atsushi Murao et al.   APOPTOSIS

Plasma mitochondrial DNA levels are associated with acute lung injury and mortality in septic patients

(2021) Jia-yu Mao et al.   BMC Pulmonary Medicine

Macrophages in Lung Injury, Repair, and Fibrosis

(2021) Peiyong Cheng et al.   Cells

Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury

(2021) Derek C. Liberti et al.   Cell Reports

The Role of Macrophages in the Pathogenesis of SARS-CoV-2-Associated Acute Respiratory Distress Syndrome

(2021) Anna Kosyreva et al.   Frontiers in Immunology

Neutrophil Extracellular Traps (NETs) in Severe SARS-CoV-2 Lung Disease

(2021) Monika Szturmowicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders

(2021) Upasana Parthasarathy et al.   BIOCHEMICAL PHARMACOLOGY

The Role of Epithelial Damage in the Pulmonary Immune Response

(2021) Rachel Ann Burgoyne et al.   Cells

Calcium-Dependent Pulmonary Inflammation and Pharmacological Interventions and Mediators

(2021) Jeffrey G. Shipman et al.   Biology-Basel

High mobility group box-1 (HMGB-1) and its receptors in the pathogenesis of malaria-associated acute lung injury/acute respiratory distress syndrome in a mouse model

(2021) Tachpon Techarang et al.   Heliyon

Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients

(2020) Julien Pottecher et al.   Trials

Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1–NKCC1 Pathway

(2020) Chin-Pyng Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HMGB1/PI3K/Akt/mTOR Signaling Participates in the Pathological Process of Acute Lung Injury by Regulating the Maturation and Function of Dendritic Cells

(2020) Ruiting Li et al.   Frontiers in Immunology

Pulmonary Innate Immune Response Determines the Outcome of Inflammation During Pneumonia and Sepsis-Associated Acute Lung Injury

(2020) Vijay Kumar   Frontiers in Immunology

Damage-Associated Molecular Patterns and Their Signaling Pathways in Primary Blast Lung Injury: New Research Progress and Future Directions

(2020) Ning Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Understanding the role of neutrophils in acute respiratory distress syndrome

(2020) Shun-Chin Yang et al.   Biomedical Journal

Autophagy alleviates mitochondrial DAMP-induced acute lung injury by inhibiting NLRP3 inflammasome

(2020) Wei Peng et al.   LIFE SCIENCES

Biomarkers for Acute Respiratory Distress syndrome and prospects for personalised medicine

(2019) Savino Spadaro et al.   Journal of Inflammation-London

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

(2019) Peter Huebener et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

(2018) Hanbyeol Lee et al.   Frontiers in Pharmacology

Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases

(2018) Serge Grazioli et al.   Frontiers in Immunology

Mitochondrial peptides cause proinflammatory responses in the alveolar epithelium via FPR-1, MAPKs, and AKT: a potential mechanism involved in acute lung injury

(2018) Xue Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cytokine profile in prediction of acute lung injury in patients with acute pancreatitis

(2018) Jayanta Samanta et al.   PANCREATOLOGY

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective

(2017) Salvatore Bongarzone et al.   JOURNAL OF MEDICINAL CHEMISTRY

RAGE inhibition reduces acute lung injury in mice

(2017) Raiko Blondonnet et al.   Scientific Reports

Decitabine and 5-azacitidine both alleviate LPS induced ARDS through anti-inflammatory/antioxidant activity and protection of glycocalyx and inhibition of MAPK pathways in mice

(2016) Xiao Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-Vascular Endothelial Growth Factor Antibody Suppresses ERK and NF-κB Activation in Ischemia-Reperfusion Lung Injury

(2016) Chou-Chin Lan et al.   PLoS One

Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation

(2014) Kiichi Nakahira et al.   PLOS MEDICINE

Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: Time course and the association with clinical status

(2013) Satoshi Yamanouchi et al.   JOURNAL OF CRITICAL CARE

Damage-Associated Molecular Patterns Control Neutrophil Recruitment

(2013) Keir Pittman et al.   Journal of Innate Immunity

Biomarkers in Acute Lung Injury—Marking Forward Progress

(2011) Nicolas Barnett et al.   CRITICAL CARE CLINICS

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE