Damage-Associated Molecular Patterns and Their Signaling Pathways in Primary Blast Lung Injury: New Research Progress and Future Directions

Epidemiology of Injuries Sustained by Civilians and Local Combatants in Contemporary Armed Conflict: An Appeal for a Shared Trauma Registry Among Humanitarian Actors

(2020) Hannah Wild et al.   WORLD JOURNAL OF SURGERY

mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury

(2020) Long Shuang Huang et al.   IMMUNITY

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

High-mobility group box 1 protein participates in acute lung injury by activating protein kinase R and inducing M1 polarization

(2020) Ruiting Li et al.   LIFE SCIENCES

Roles of S100 family members in drug resistance in tumors: Status and prospects

(2020) Xin Hua et al.   BIOMEDICINE & PHARMACOTHERAPY

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

Mesenchymal Stem/Stromal Cells Therapy for Sepsis and Acute Respiratory Distress Syndrome

(2020) Declan Byrnes et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular CIRP (eCIRP) and inflammation

(2019) Monowar Aziz et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Blast injures to the thorax

(2019) Zsolt Sziklavari et al.   Journal of Thoracic Disease

High-Mobility Group Box 1 (HMGB1) and Autophagy in Acute Lung Injury (ALI): A Review

(2019) Lihua Qu et al.   MEDICAL SCIENCE MONITOR

Early Complement and Fibrinolytic Activation in a Rat Model of Blast-Induced Multi-Organ Damage

(2019) Zhangsheng Yang et al.   MILITARY MEDICINE

NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow

(2019) Mariusz Z. Ratajczak et al.   LEUKEMIA

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury

(2019) Chiara Poluzzi et al.   KIDNEY INTERNATIONAL

Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy

(2019) Heiko Roedig et al.   FEBS Journal

Thoracic Injury in Patients Injured by Explosions on the Battlefield and in Terrorist Incidents

(2019) Andrew McDonald Johnston et al.   CHEST

Damage-associated molecular patterns in trauma

(2019) Borna Relja et al.   European Journal of Trauma and Emergency Surgery

VEGF mediates fat embolism-induced acute lung injury via VEGF receptor 2 and the MAPK cascade

(2019) Chin-Kuo Lin et al.   Scientific Reports

Extracellular mitochondrial DNA promote NLRP3 inflammasome activation and induce acute lung injury through TLR9 and NF-κB

(2019) Guannan Wu et al.   Journal of Thoracic Disease

Management of combined massive burn and blast injury: A 20-year experience

(2019) Xing-feng Zheng et al.   BURNS

Regulation of cGAS- and RLR-mediated immunity to nucleic acids

(2019) Andrea Ablasser et al.   NATURE IMMUNOLOGY

Targeting RAGE Signaling in Inflammatory Disease

(2018) Barry I. Hudson et al.   Annual Review of Medicine

Yes-Associated Protein Promotes Angiogenesis via Signal Transducer and Activator of Transcription 3 in Endothelial CellsNovelty and Significance

(2018) Jinlong He et al.   CIRCULATION RESEARCH

YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6Novelty and Significance

(2018) Yang Lv et al.   CIRCULATION RESEARCH

High molecular weight hyaluronan attenuates fine particulate matter-induced acute lung injury through inhibition of ROS-ASK1-p38/JNK-mediated epithelial apoptosis

(2018) Chenming Xu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Danger signals in trauma

(2018) Borna Relja et al.   European Journal of Trauma and Emergency Surgery

Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse model

(2018) Changci Tong et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Primary Blast Brain Injury Mechanisms: Current Knowledge, Limitations, and Future Directions

(2018) Elizabeth Fievisohn et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity

(2018) Charles W. Frevert et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

(2018) Takanori Komada et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Biglycan is a new high-affinity ligand for CD14 in macrophages

(2018) Heiko Roedig et al.   MATRIX BIOLOGY

Hyaluronan interactions with innate immunity in lung biology

(2018) Robert M. Tighe et al.   MATRIX BIOLOGY

Extracellular ATP is a danger signal activating P2X7 Receptor in a LPS mediated inflammation (ARDS/ALI)

(2018) Sanja Cicko et al.   Oncotarget

Trauma-Induced Damage-Associated Molecular Patterns-Mediated Remote Organ Injury and Immunosuppression in the Acutely Ill Patient

(2018) Mickael Vourc’h et al.   Frontiers in Immunology

Danger-Associated Molecular Patterns (DAMPs): the Derivatives and Triggers of Inflammation

(2018) Seema Patel   CURRENT ALLERGY AND ASTHMA REPORTS

Complement inhibition ameliorates blast-induced acute lung injury in rats: Potential role of complement in intracellular HMGB1-mediated inflammation

(2018) Yansong Li et al.   PLoS One

Control of Inflammasome Activation by Phosphorylation

(2018) Tao Gong et al.   TRENDS IN BIOCHEMICAL SCIENCES

Formyl-Peptide Receptors in Infection, Inflammation, and Cancer

(2018) Elisabeth Weiß et al.   TRENDS IN IMMUNOLOGY

Changes in TNF-α, IL-6, IL-10 and VEGF in rats with ARDS and the effects of dexamethasone

(2018) Mengting Qin et al.   Experimental and Therapeutic Medicine

Pathophysiology of primary blast injury

(2018) Jason E Smith et al.   Journal of the Royal Army Medical Corps

The P2X7 Receptor in Infection and Inflammation

(2017) Francesco Di Virgilio et al.   IMMUNITY

Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment

(2017) Juciano Gasparotto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Group A streptococcal pharyngitis: immune responses involved in bacterial clearance and GAS-associated immunopathologies

(2017) Amelia T. Soderholm et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of airway inflammation and remodeling in asthmatic mice by TLR3/TRIF signal pathway

(2017) Mei Yang et al.   MOLECULAR IMMUNOLOGY

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

(2017) Alessandra Tammaro et al.   PHARMACOLOGY & THERAPEUTICS

Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells

(2017) Zhaorui Zhang et al.   PLoS One

The role of extracellular histone in organ injury

(2017) Eleanor Silk et al.   Cell Death & Disease

Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner

(2017) Deblina Chakraborty et al.   Frontiers in Immunology

Acute Lung Injury: A Clinical and Molecular Review

(2016) Yasmeen Butt et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

(2016) Damien Bertheloot et al.   Cellular & Molecular Immunology

Key Role of DAMP in Inflammation, Cancer, and Tissue Repair

(2016) Franco Pandolfi et al.   CLINICAL THERAPEUTICS

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

(2016) Felix L. Yeh et al.   NEURON

Therapeutic targeting of acute lung injury and acute respiratory distress syndrome

(2016) Theodore J. Standiford et al.   Translational Research

Effectiveness of hyaluronic acid and its derivatives on chronic wounds: a systematic review

(2016) A. Shaharudin et al.   Journal of Wound Care

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Blast Injuries

(2015) Zara R. Mathews et al.   JOURNAL OF EMERGENCY MEDICINE

Mincle Signaling in the Innate Immune Response after Traumatic Brain Injury

(2015) Juan Carlos de Rivero Vaccari et al.   JOURNAL OF NEUROTRAUMA

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

DAMPs from Cell Death to New Life

(2015) Emilie Vénéreau et al.   Frontiers in Immunology

Extracellular matrix regulation of inflammation in the healthy and injured spinal cord

(2014) Andrew D. Gaudet et al.   EXPERIMENTAL NEUROLOGY

Unknown

(2014) Chunhua Jin et al.   MOLECULAR MEDICINE

HSP60 is involved in the neuroprotective effects of naloxone

(2014) WENJING CHENG et al.   Molecular Medicine Reports

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Circulating Histones Are Mediators of Trauma-associated Lung Injury

(2012) Simon T. Abrams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Functions of S100 Proteins

(2012) R. Donato et al.   CURRENT MOLECULAR MEDICINE

Danger-associated molecular patterns (DAMPs) in acute lung injury

(2012) Leslie B Tolle et al.   JOURNAL OF PATHOLOGY

Primary Blast Injuries—An Updated Concise Review

(2012) Daniel Dante Yeh et al.   WORLD JOURNAL OF SURGERY

Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

(2012) Manuela Rossol et al.   Nature Communications

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Transient receptor potential channels as therapeutic targets

(2011) Magdalene M. Moran et al.   NATURE REVIEWS DRUG DISCOVERY

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice

(2010) Ken-Ichiro Tanaka et al.   BIOCHEMICAL PHARMACOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Characterization of the response to primary blast injury

(2010) E. Kirkman et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Blast injuries to the lung: epidemiology and management

(2010) I. M. J. Mackenzie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

Interleukin-10: new perspectives on an old cytokine

(2009) David M. Mosser et al.   IMMUNOLOGICAL REVIEWS

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

(2009) Luisa Stefano et al.   JOURNAL OF NEUROCHEMISTRY

Blast injuries

(2009) Stephen J Wolf et al.   LANCET

Vascular endothelial growth factor receptor and coreceptor expression in human acute respiratory distress syndrome

(2008) Andrew R.L. Medford et al.   JOURNAL OF CRITICAL CARE

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

(2008) Bente K. Pedersen et al.   PHYSIOLOGICAL REVIEWS

Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases

(2008) Eva Lorenz et al.   RESPIRATORY MEDICINE

TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer

(2007) Chao-Chi Ho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE