Total astragalosides promote oligodendrocyte precursor cell differentiation and enhance remyelination in cuprizone-induced mice through suppression of Wnt/β-catenin signaling pathway

Total astragalosides decrease apoptosis and pyroptosis by inhibiting enterovirus 71 replication in gastric epithelial cells

(2022) Xiaoyan Zhang et al.   Experimental and Therapeutic Medicine

Astragalus species: Phytochemistry, biological actions and molecular mechanisms underlying their potential neuroprotective effects on neurological diseases

(2022) Heba-Tallah Abd Elrahim Abd Elkader et al.   PHYTOCHEMISTRY

Recent advances on immunosuppressive drugs and remyelination enhancers for the treatment of multiple sclerosis

(2021) Jennifer Cadenas-Fernández et al.   CURRENT PHARMACEUTICAL DESIGN

Diagnosis and Treatment of Multiple Sclerosis

(2021) Marisa P. McGinley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Early Aggressive Treatment Approaches for Multiple Sclerosis

(2021) Alexandra Simpson et al.   Current Treatment Options in Neurology

Murine Esophagus Expresses Glial-Derived Central Nervous System Antigens

(2021) Christopher Kapitza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astragaloside alleviates alcoholic fatty liver disease by suppressing oxidative stress

(2021) Zhi‐Bin Jiang et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Galangin Inhibits Gastric Cancer Growth Through Enhancing STAT3 Mediated ROS Production

(2021) Xiaohui Liang et al.   Frontiers in Pharmacology

DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation

(2021) Assia Tiane et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Astragalus saponins improves stroke by promoting the proliferation of neural stem cells through phosphorylation of Akt

(2021) Yu Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Secondary Progressive Multiple Sclerosis

(2021) Bruce A.C. Cree et al.   NEUROLOGY

Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway

(2021) Qi Shao et al.   Neuroscience Bulletin

Remyelination: what are the prospects for regenerative therapies in multiple sclerosis?

(2021) Jonathan D. Moore   Emerging Topics in Life Sciences

Early astragaloside IV administration attenuates experimental autoimmune encephalomyelitis in mice by suppressing the maturation and function of dendritic cells

(2020) Liu Yang et al.   LIFE SCIENCES

T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis

(2020) Martina Kunkl et al.   Cells

Cognitive disturbances in the cuprizone model of multiple sclerosis

(2020) Maksym V. Kopanitsa et al.   GENES BRAIN AND BEHAVIOR

A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination

(2020) Yuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Senescence and Failure of Myelin Repair in Multiple Sclerosis

(2020) Paraskevi N. Koutsoudaki et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Total flavonoids of astragalus attenuates experimental autoimmune encephalomyelitis by suppressing the activation and inflammatory responses of microglia via JNK/AKT/NFκB signaling pathway

(2020) Liu Yang et al.   PHYTOMEDICINE

Remyelination in multiple sclerosis

(2019) David Kremer et al.   CURRENT OPINION IN NEUROLOGY

The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides

(2019) Yu Sun et al.   JOURNAL OF NEUROIMMUNOLOGY

Promoting remyelination in multiple sclerosis

(2019) Nick Cunniffe et al.   JOURNAL OF NEUROLOGY

The Molecular Basis for Remyelination Failure in Multiple Sclerosis

(2019) Joel Gruchot et al.   Cells

Oligodendrocytes in Development, Myelin Generation and Beyond

(2019) Sarah Kuhn et al.   Cells

Behavioural phenotypes in the cuprizone model of central nervous system demyelination

(2019) Monokesh K. Sen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Long‐term stability and characteristics of behavioral, biochemical, and molecular markers of three different rodent models for depression

(2019) Han Zhu et al.   Brain and Behavior

Current advancements in promoting remyelination in multiple sclerosis

(2018) David Kremer et al.   Multiple Sclerosis Journal

Astragaloside IV regulates differentiation and induces apoptosis of activated CD4+ T cells in the pathogenesis of experimental autoimmune encephalomyelitis

(2018) Liu Yang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Drug discovery for remyelination and treatment of MS

(2017) Katy L. H. Cole et al.   GLIA

Transcription factor 7 like 2 promotes oligodendrocyte differentiation and remyelination

(2017) Chao Weng et al.   Molecular Medicine Reports

Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?

(2017) Lorenzo Di Cesare Mannelli et al.   Scientific Reports

The Antioxidant Effects of Radix Astragali (Astragalus membranaceus and Related Species) in Protecting Tissues from Injury and Disease

(2016) Muhammad Shahzad et al.   CURRENT DRUG TARGETS

Intracellular signaling pathway regulation of myelination and remyelination in the CNS

(2016) Jenna M. Gaesser et al.   EXPERIMENTAL NEUROLOGY

A systematic review of anticancer effects of Radix Astragali

(2015) Yeehong Jung et al.   Chinese Journal of Integrative Medicine

Thyroid hormone alleviates demyelination induced by cuprizone through its role in remyelination during the remission period

(2015) Mao Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Temporal oligodendrocyte lineage progression: In vitro models of proliferation, differentiation and myelination

(2014) Andreia Barateiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Astragalosides from Radix Astragali benefits experimental autoimmune encephalomyelitis in C57BL /6 mice at multiple levels

(2014) Yi-Xin He et al.   BMC Complementary and Alternative Medicine

GSK3β Promotes the Differentiation of Oligodendrocyte Precursor Cells via β-Catenin-Mediated Transcriptional Regulation

(2014) Liang Zhou et al.   MOLECULAR NEUROBIOLOGY

Astragaloside IV Attenuates Experimental Autoimmune Encephalomyelitis of Mice by Counteracting Oxidative Stress at Multiple Levels

(2013) Yixin He et al.   PLoS One