Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway

Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis

(2020) Wei Wang et al.   MOLECULAR MEDICINE

Lesion stage-dependent causes for impaired remyelination in MS

(2020) Katharina Heß et al.   ACTA NEUROPATHOLOGICA

Shikimic Acid Promotes Oligodendrocyte Precursor Cell Differentiation and Accelerates Remyelination in Mice

(2019) Fengfeng Lu et al.   Neuroscience Bulletin

Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination

(2018) Yanqing Shi et al.   Neuroscience Bulletin

Pinocembrin enriched fraction of Elytranthe parasitica (L.) Danser induces apoptosis in HCT 116 colorectal cancer cells

(2017) Nimmy Kumar et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Chemical Constituents of Supercritical Extracts from Alpinia officinarum and the Feeding Deterrent Activity against Tribolium castaneum

(2017) Mintong Xin et al.   MOLECULES

Intracellular signaling pathway regulation of myelination and remyelination in the CNS

(2016) Jenna M. Gaesser et al.   EXPERIMENTAL NEUROLOGY

Disulfiram and Diphenhydramine Hydrochloride Upregulate miR-30a to Suppress IL-17-Associated Autoimmune Inflammation

(2016) M. Zhao et al.   JOURNAL OF NEUROSCIENCE

Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells

(2016) Yumin Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Pinocembrin attenuates MPP + -induced neurotoxicity by the induction of heme oxygenase-1 through ERK1/2 pathway

(2016) Hongquan Wang et al.   NEUROSCIENCE LETTERS

Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats

(2016) Kalist Shagirtha et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Pinocembrin reduces cardiac arrhythmia and infarct size in rats subjected to acute myocardial ischemia/reperfusion

(2015) Anusorn Lungkaphin et al.   Applied Physiology Nutrition and Metabolism

MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination

(2015) Z. Yu et al.   JOURNAL OF NEUROSCIENCE

Multiple sclerosis drugs: how much bang for the buck?

(2015) Olaf Stüve et al.   LANCET NEUROLOGY

Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin

(2015) Mehrdad Iranshahi et al.   LIFE SCIENCES

The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications

(2015) Xi Lan et al.   MOLECULAR NEUROBIOLOGY

Pinocembrin attenuates hippocampal inflammation, oxidative perturbations and apoptosis in a rat model of global cerebral ischemia reperfusion

(2015) Muhammed A. Saad et al.   Pharmacological Reports

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional and Epigenetic Regulation of Oligodendrocyte Development and Myelination in the Central Nervous System

(2015) Ben Emery et al.   Cold Spring Harbor Perspectives in Biology

TIP30 inhibits oligodendrocyte precursor cell differentiation via cytoplasmic sequestration of Olig1

(2014) Wenjing Yang et al.   GLIA

Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits

(2014) Rui Liu et al.   NEUROBIOLOGY OF AGING

Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models

(2014) Hamideh Parhiz et al.   PHYTOTHERAPY RESEARCH

NMDA receptor couples Rac1-GEF Tiam1 to direct oligodendrocyte precursor cell migration

(2013) Lin Xiao et al.   GLIA

A functional role of NMDA receptor in regulating the differentiation of oligodendrocyte precursor cells and remyelination

(2013) Cui Li et al.   GLIA

Mechanisms regulating the development of oligodendrocytes and central nervous system myelin

(2013) S. Mitew et al.   NEUROSCIENCE

Regulation of the timing of oligodendrocyte differentiation: mechanisms and perspectives

(2013) Hao Huang et al.   Neuroscience Bulletin

Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities

(2013) Azhar Rasul et al.   Biomed Research International

Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages

(2012) Deok-Sung Bae et al.   BMB Reports

In vitro and in vivo protection provided by pinocembrin against lipopolysaccharide-induced inflammatory responses

(2012) Lanan Wassy Soromou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

LINGO-1, a Transmembrane Signaling Protein, Inhibits Oligodendrocyte Differentiation and Myelination through Intercellular Self-interactions

(2012) Scott Jepson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-inflammatory flavonoids from Cryptocarya chingii

(2012) Rui Feng et al.   PHYTOCHEMISTRY

Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines

(2011) Chun-Han Chen et al.   CANCER LETTERS

Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation

(2011) Hebe M. Guardiola-Diaz et al.   GLIA

1H-NMR Simultaneous Identification of Health-Relevant Compounds in Propolis Extracts

(2011) Davide Bertelli et al.   PHYTOCHEMICAL ANALYSIS

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia–reperfusion both in vivo and in vitro

(2008) Rui Liu et al.   BRAIN RESEARCH

Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey

(2008) Letícia Estevinho et al.   FOOD AND CHEMICAL TOXICOLOGY

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE