A risk-based approach for cell line development, manufacturing and characterization of genetically engineered, induced pluripotent stem cell–derived allogeneic cell therapies
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Title
A risk-based approach for cell line development, manufacturing and characterization of genetically engineered, induced pluripotent stem cell–derived allogeneic cell therapies
Authors
Keywords
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Journal
CYTOTHERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2022-09-13
DOI
10.1016/j.jcyt.2022.08.001
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Note: Only part of the references are listed.- Development of an induced pluripotent stem cell–specific microRNA assay for detection of residual undifferentiated cells in natural killer cell therapy products
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- (2021) Colin M. Young et al. DRUG DISCOVERY TODAY
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- (2021) Amin Allahyar et al. Nature Communications
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- (2021) Eva Kriegova et al. Scientific Reports
- Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
- (2020) Oliver Thompson et al. Nature Communications
- Publisher Correction: The mutational impact of culturing human pluripotent and adult stem cells
- (2020) Ewart Kuijk et al. Nature Communications
- Robust detection of undifferentiated iPSC among differentiated cells
- (2020) Keisuke Sekine et al. Scientific Reports
- Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing
- (2020) Muhammad Naeem et al. Cells
- Detection and Modulation of DNA Translocations During Multi-Gene Genome Editing in T Cells
- (2020) Anne Bothmer et al. CRISPR Journal
- CiRA iPSC seed stocks (CiRA's iPSC Stock Project)
- (2020) Tadaaki Hanatani et al. Stem Cell Research
- Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones
- (2020) Richard H. Smith et al. Genes
- Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients
- (2019) Tobias Deuse et al. NATURE BIOTECHNOLOGY
- Generation of hypoimmunogenic human pluripotent stem cells
- (2019) Xiao Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Considering “clonality”: A regulatory perspective on the importance of the clonal derivation of mammalian cell banks in biopharmaceutical development
- (2019) Joel T. Welch et al. BIOLOGICALS
- Tumorigenicity assessment of cell therapy products: The need for global consensus and points to consider
- (2019) Y. Sato et al. CYTOTHERAPY
- UDiTaS™, a genome editing detection method for indels and genome rearrangements
- (2018) Georgia Giannoukos et al. BMC GENOMICS
- Quality control guidelines for clinical-grade human induced pluripotent stem cell lines
- (2018) Stephen Sullivan et al. Regenerative Medicine
- Mapping the genomic landscape of CRISPR–Cas9 cleavage
- (2017) Peter Cameron et al. NATURE METHODS
- BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
- (2017) Winston X. Yan et al. Nature Communications
- Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing
- (2016) Jiazhi Hu et al. Nature Protocols
- Application of cell growth analysis to the quality assessment of human cell-processed therapeutic products as a testing method for immortalized cellular impurities
- (2016) Nozomi Hasebe-Takada et al. Regenerative Therapy
- Characterization of the cell growth analysis for detection of immortal cellular impurities in human mesenchymal stem cells
- (2015) Ken Kono et al. BIOLOGICALS
- Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
- (2015) Xiaoling Wang et al. NATURE BIOTECHNOLOGY
- Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
- (2015) Daesik Kim et al. NATURE METHODS
- Ultra-sensitive detection of tumorigenic cellular impurities in human cell-processed therapeutic products by digital analysis of soft agar colony formation
- (2015) Shinji Kusakawa et al. Scientific Reports
- Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells
- (2015) Takuya Kuroda et al. Regenerative Therapy
- Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
- (2014) S. Bae et al. BIOINFORMATICS
- Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
- (2014) Adrian Veres et al. Cell Stem Cell
- Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping
- (2014) Paula J P de Vree et al. NATURE BIOTECHNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Anchored multiplex PCR for targeted next-generation sequencing
- (2014) Zongli Zheng et al. NATURE MEDICINE
- CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
- (2014) Tessa G. Montague et al. NUCLEIC ACIDS RESEARCH
- COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites
- (2014) Thomas J Cradick et al. Molecular Therapy-Nucleic Acids
- TALENoffer: genome-wide TALEN off-target prediction
- (2013) Jan Grau et al. BIOINFORMATICS
- Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies
- (2013) Andrew S Lee et al. NATURE MEDICINE
- Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
- (2013) Nicola Crosetto et al. NATURE METHODS
- Generating an iPSC Bank for HLA-Matched Tissue Transplantation Based on Known Donor and Recipient HLA Types
- (2012) Craig J. Taylor et al. Cell Stem Cell
- Lessons from human teratomas to guide development of safe stem cell therapies
- (2012) Justine J Cunningham et al. NATURE BIOTECHNOLOGY
- Highly Sensitive In Vitro Methods for Detection of Residual Undifferentiated Cells in Retinal Pigment Epithelial Cells Derived from Human iPS Cells
- (2012) Takuya Kuroda et al. PLoS One
- Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes
- (2011) Isaac A. Klein et al. CELL
- Effects of cell number on teratoma formation by human embryonic stem cells
- (2011) Andrew S. Lee et al. CELL CYCLE
- Genome structural variation discovery and genotyping
- (2011) Can Alkan et al. NATURE REVIEWS GENETICS
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Teratoma formation by human embryonic stem cells: Evaluation of essential parameters for future safety studies
- (2009) Hannes Hentze et al. Stem Cell Research
- Systematic assessment of copy number variant detection via genome-wide SNP genotyping
- (2008) Gregory M Cooper et al. NATURE GENETICS
- Integrated detection and population-genetic analysis of SNPs and copy number variation
- (2008) Steven A McCarroll et al. NATURE GENETICS
- Teratoma Formation by Human Embryonic Stem Cells Is Site Dependent and Enhanced by the Presence of Matrigel
- (2008) Tatyana A. Prokhorova et al. STEM CELLS AND DEVELOPMENT
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