Lessons from human teratomas to guide development of safe stem cell therapies

Malignant Germ Cell–Like Tumors, Expressing Ki-1 Antigen (CD30), Are Revealed during in Vivo Differentiation of Partially Reprogrammed Human-Induced Pluripotent Stem Cells

(2012) Frank Griscelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Ultrasensitive Microarray Detection of Short RNA Sequences with Enzymatically Modified Nanoparticles and Surface Plasmon Resonance Imaging Measurements

(2011) Wen-Juan Zhou et al.   ANALYTICAL CHEMISTRY

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours

(2011) M A Rijlaarsdam et al.   BRITISH JOURNAL OF CANCER

Effects of cell number on teratoma formation by human embryonic stem cells

(2011) Andrew S. Lee et al.   CELL CYCLE

Blimp1 Expression Predicts Embryonic Stem Cell Development In Vitro

(2011) Li-Fang Chu et al.   CURRENT BIOLOGY

Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis

(2011) A. J. M. Gillis et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Altered patterns of differentiation in karyotypically abnormal human embryonic stem cells

(2011) Alireza Fazeli et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells

(2011) Chad Tang et al.   NATURE BIOTECHNOLOGY

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

Early Events in Xenograft Development from the Human Embryonic Stem Cell Line HS181 - Resemblance with an Initial Multiple Epiblast Formation

(2011) Karin Gertow et al.   PLoS One

Residual Undifferentiated Cells During Differentiation of Induced Pluripotent Stem Cells In Vitro and In Vivo

(2011) Wei Fu et al.   STEM CELLS AND DEVELOPMENT

Astrocytes derived from trisomic human embryonic stem cells express markers of astrocytic cancer cells and premalignant stem-like progenitors

(2010) Sailesh Gopalakrishna-Pillai et al.   BMC Medical Genomics

Malignant transformation of an untreated congenital sacrococcygeal teratoma: a amplification at 8q and 12p detected by comparative genomic hybridization

(2010) Mariola Monika Golas et al.   CANCER GENETICS AND CYTOGENETICS

Effects of MRI Contrast Agents on the Stem Cell Phenotype

(2010) Annelies Crabbe et al.   CELL TRANSPLANTATION

DNMT3L Is a Novel Marker and Is Essential for the Growth of Human Embryonal Carcinoma

(2010) K. Minami et al.   CLINICAL CANCER RESEARCH

Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation

(2010) Weijun Su et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Effect of chromosome instability on the maintenance and differentiation of human embryonic stem cells in vitro and in vivo

(2010) Sung-Hwan Moon et al.   Stem Cell Research

Detection of MicroRNA by Fluorescence Amplification Based on Cation-Exchange in Nanocrystals

(2009) Jishan Li et al.   ANALYTICAL CHEMISTRY

Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V

(2009) Tahereh Tavakoli et al.   BMC CELL BIOLOGY

Noninvasive De novo Imaging of Human Embryonic Stem Cell-Derived Teratoma Formation

(2009) F. Cao et al.   CANCER RESEARCH

Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes

(2009) Shinsuke Furukawa et al.   CANCER SCIENCE

Analytical validation of a highly sensitive microparticle-based immunoassay for the quantitation of IL-13 in human serum using the Erenna® immunoassay system

(2009) Katie St. Ledger et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Characterization of human embryonic stem cells with features of neoplastic progression

(2009) Tamra E Werbowetski-Ogilvie et al.   NATURE BIOTECHNOLOGY

Teratoma formation by human embryonic stem cells: Evaluation of essential parameters for future safety studies

(2009) Hannes Hentze et al.   Stem Cell Research

Long-Term Safety and Function of RPE from Human Embryonic Stem Cells in Preclinical Models of Macular Degeneration

(2009) Bin Lu et al.   STEM CELLS

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

(2008) R. D. Morin et al.   GENOME RESEARCH

Immunohistochemical localization of nanog and Oct4 in stem cell compartments of human sacrococcygeal teratomas

(2008) C Busch et al.   HISTOPATHOLOGY

The distribution and behavior of extragonadal primordial germ cells in Bax mutant mice suggest a novel origin for sacrococcygeal germ cell tumors

(2008) Christopher Runyan et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Isolation of three stem cell lines from human sacrococcygeal teratomas

(2008) Christian Busch et al.   JOURNAL OF PATHOLOGY

Go with the flowfor monitoring response in myeloma with minimal residual disease

(2008) Kylie D. Mason et al.   LEUKEMIA & LYMPHOMA

Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors

(2008) Georges J Netto et al.   MODERN PATHOLOGY

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Recurrent chromosomal abnormalities in human embryonic stem cells

(2008) Claudia Spits et al.   NATURE BIOTECHNOLOGY

Teratoma Formation by Human Embryonic Stem Cells Is Site Dependent and Enhanced by the Presence of Matrigel

(2008) Tatyana A. Prokhorova et al.   STEM CELLS AND DEVELOPMENT

Polycomb Group Genes: Keeping Stem Cell Activity in Balance

(2008) Martin Sauvageau et al.   PLOS BIOLOGY

Real-time PCR quantification of precursor and mature microRNA

(2007) Thomas D. Schmittgen et al.   METHODS