Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
Authors
Keywords
-
Journal
NATURE BIOTECHNOLOGY
Volume 33, Issue 2, Pages 175-178
Publisher
Springer Nature
Online
2015-01-20
DOI
10.1038/nbt.3127
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
- (2014) Y. Lin et al. NUCLEIC ACIDS RESEARCH
- Precise Gene Modification Mediated by TALEN and Single-Stranded Oligodeoxynucleotides in Human Cells
- (2014) Xiaoling Wang et al. PLoS One
- PEAR: a fast and accurate Illumina Paired-End reAd mergeR
- (2013) J. Zhang et al. BIOINFORMATICS
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- TALEN-based Gene Correction for Epidermolysis Bullosa
- (2013) Mark J Osborn et al. MOLECULAR THERAPY
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
- (2013) Vikram Pattanayak et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish
- (2013) An Xiao et al. NUCLEIC ACIDS RESEARCH
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
- (2012) Erin L. Doyle et al. NUCLEIC ACIDS RESEARCH
- An unbiased genome-wide analysis of zinc-finger nuclease specificity
- (2011) Richard Gabriel et al. NATURE BIOTECHNOLOGY
- Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
- (2011) Vikram Pattanayak et al. NATURE METHODS
- Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing
- (2010) Anna Paruzynski et al. Nature Protocols
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started