Polystyrene nanoplastics deteriorate LPS-modulated duodenal permeability and inflammation in mice via ROS drived-NF-κB/NLRP3 pathway

Polystyrene nanoplastics induced cardiomyocyte apoptosis and myocardial inflammation in carp by promoting ROS production

(2022) Hao Wu et al.   FISH & SHELLFISH IMMUNOLOGY

Polystyrene micro and nano-particles induce metabolic rewiring in normal human colon cells: A risk factor for human health

(2022) Marcella Bonanomi et al.   CHEMOSPHERE

Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice

(2022) Hao Wu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

E-cigarettes compromise the gut barrier and trigger inflammation

(2021) Aditi Sharma et al.   iScience

Induction of protective response to polystyrene nanoparticles associated with methylation regulation in Caenorhabditis elegans

(2021) Shuting Wang et al.   CHEMOSPHERE

Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids

(2021) Mohamed Elbadawi et al.   PHYTOMEDICINE

Tissue distribution of polystyrene nanoplastics in mice and their entry, transport, and cytotoxicity to GES-1 cells

(2021) Yunfei Ding et al.   ENVIRONMENTAL POLLUTION

Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes

(2021) Wang Shengchen et al.   JOURNAL OF HAZARDOUS MATERIALS

Heterogeneity effects of nanoplastics and lead on zebrafish intestinal cells identified by single-cell sequencing

(2021) Jing Yu et al.   CHEMOSPHERE

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

(2021) Yanting Pang et al.   Redox Biology

The potential effects of microplastic pollution on human digestive tract cells

(2021) Yuting Zhang et al.   CHEMOSPHERE

Single-Cell RNA Sequencing Reveals Size-Dependent Effects of Polystyrene Microplastics on Immune and Secretory Cell Populations from Zebrafish Intestines

(2020) Weiqing Gu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure

(2020) Sreeja Sarasamma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier

(2020) Josefa Domenech et al.   ARCHIVES OF TOXICOLOGY

Nano-plastics and their analytical characterisation and fate in the marine environment: From source to sea

(2020) Sheeana Gangadoo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polystyrene microplastics (PS-MPs) toxicity induced oxidative stress and intestinal injury in nematode Caenorhabditis elegans

(2020) Yunjiang Yu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats

(2020) Zekang Li et al.   ENVIRONMENTAL POLLUTION

Neurotoxic potential of polystyrene nanoplastics in primary cells originating from mouse brain

(2020) Byung-Kwon Jung et al.   NEUROTOXICOLOGY

Proinflammatory properties and lipid disturbance of polystyrene microplastics in the livers of mice with acute colitis

(2020) Haibin Zheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Molecular Mechanisms That Link Oxidative Stress, Inflammation, and Fibrosis in the Liver

(2020) Erika Ramos-Tovar et al.   Antioxidants

Amorphous silica nanoparticles induce inflammation via activation of NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-kb signaling pathway in HUVEC cells

(2020) Xuting Liu et al.   JOURNAL OF HAZARDOUS MATERIALS

Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells

(2019) Bing Wu et al.   CHEMOSPHERE

In vitro intestinal toxicity of copper oxide nanoparticles in rat and human cell models

(2019) Taylor E. Henson et al.   Nanotoxicology

Progress in Mycotoxins Affecting Intestinal Mucosal Barrier Function

(2019) Zhihua Ren et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Silica nanoparticles disrupt OPT-2/PEP-2-dependent trafficking of nutrient peptides in the intestinal epithelium

(2019) A. Piechulek et al.   Nanotoxicology

Hydrogen Sulfide Gas Exposure Induces Necroptosis and Promotes Inflammation through the MAPK/NF-κB Pathway in Broiler Spleen

(2019) Qianru Chi et al.   Oxidative Medicine and Cellular Longevity

Maternal Polystyrene Microplastic Exposure during Gestation and Lactation Altered Metabolic Homeostasis in the Dams and Their F1 and F2 Offspring

(2019) Ting Luo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bisphenol A increases intestinal permeability through disrupting intestinal barrier function in mice

(2019) Ling Feng et al.   ENVIRONMENTAL POLLUTION

Micro- and nano-plastics in marine environment: Source, distribution and threats — A review

(2019) Licheng Peng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell

(2019) Mingkai Xu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Impact of chronic exposure to trichlorfon on intestinal barrier, oxidative stress, inflammatory response and intestinal microbiome in common carp (Cyprinus carpio L.)

(2019) Xulu Chang et al.   ENVIRONMENTAL POLLUTION

Current opinion: What is a nanoplastic?

(2018) Julien Gigault et al.   ENVIRONMENTAL POLLUTION

Role and mechanism of ROS scavengers in alleviating NLRP3-mediated inflammation

(2018) Takami Sho et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Uptake and molecular impact of aluminum-containing nanomaterials on human intestinal caco-2 cells

(2018) Holger Sieg et al.   Nanotoxicology

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

Widespread microplastic ingestion by fish assemblages in tropical estuaries subjected to anthropogenic pressures

(2017) A.L. Vendel et al.   MARINE POLLUTION BULLETIN

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation induced by zinc oxide nanoparticles in A549 cells

(2017) Xiao Liang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

(2017) Sarah Bettini et al.   Scientific Reports

The effect of titanium dioxide nanoparticles on neuroinflammation response in rat brain

(2016) Intissar Grissa et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Size and dose dependent effects of silver nanoparticle exposure on intestinal permeability in an in vitro model of the human gut epithelium

(2016) Katherine M. Williams et al.   JOURNAL OF NANOBIOTECHNOLOGY

In vitrogastrointestinal digestion increases the translocation of polystyrene nanoparticles in anin vitrointestinal co-culture model

(2015) Agata P. Walczak et al.   Nanotoxicology

Plastic waste inputs from land into the ocean

(2015) J. R. Jambeck et al.   SCIENCE

Intestinal permeability – a new target for disease prevention and therapy

(2014) Stephan C Bischoff et al.   BMC GASTROENTEROLOGY

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

(2013) Amarjargal Dashdorj et al.   BMC Medicine

Oral exposure to polystyrene nanoparticles affects iron absorption

(2012) Gretchen J. Mahler et al.   Nature Nanotechnology

Histological alterations in the liver of rats induced by different gold nanoparticle sizes, doses and exposure duration

(2012) Mohamed Abdelhalim et al.   JOURNAL OF NANOBIOTECHNOLOGY

Maternal exposure to carbon black nanoparticle increases collagen type VIII expression in the kidney of offspring

(2011) Masakazu Umezawa et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

A New Role for Intestinal Alkaline Phosphatase in Gut Barrier Maintenance

(2008) Kaoru Geddes et al.   GASTROENTEROLOGY