Co-transplantation of Islets-Laden Microgels and Biodegradable O2-Generating Microspheres for Diabetes Treatment

Assembling Microgels via Dynamic Cross-Linking Reaction Improves Printability, Microporosity, Tissue-Adhesion, and Self-Healing of Microgel Bioink for Extrusion Bioprinting

(2022) Qi Feng et al.   ACS Applied Materials & Interfaces

An inverse-breathing encapsulation system for cell delivery

(2021) Long-Hai Wang et al.   Science Advances

Engineering a macroporous oxygen-generating scaffold for enhancing islet cell transplantation within an extrahepatic site

(2021) Jia-Pu Liang et al.   Acta Biomaterialia

Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

(2021) Yasaman Aghazadeh et al.   Cell Stem Cell

The impact of locally-delivered tacrolimus-releasing microspheres and polyethylene glycol-based islet surface modification on xenogeneic islet survival

(2021) Tiep Tien Nguyen et al.   JOURNAL OF CONTROLLED RELEASE

Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?

(2021) Jean-Claude Henquin   Molecular Metabolism

Microgel assembly: Fabrication, characteristics and application in tissue engineering and regenerative medicine

(2021) Qi Feng et al.   Bioactive Materials

Dynamic Nanocomposite Microgel Assembly with Microporosity, Injectability, Tissue‐Adhesion, and Sustained Drug Release Promotes Articular Cartilage Repair and Regeneration

(2021) Qi Feng et al.   Advanced Healthcare Materials

Transplantation of Islet-Containing microcapsules modified with constitutional isomers of sulfated alginate in diabetic mice to mitigate fibrosis for Long-term glycemic control

(2021) Zakieh Samsonchi et al.   CHEMICAL ENGINEERING JOURNAL

A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation

(2020) Mehdi Razavi et al.   ADVANCED FUNCTIONAL MATERIALS

Genetics of diabetes mellitus and diabetes complications

(2020) Joanne B. Cole et al.   Nature Reviews Nephrology

A Droplet Microfluidic System to Fabricate Hybrid Capsules Enabling Stem Cell Organoid Engineering

(2020) Haitao Liu et al.   Advanced Science

Engineering the cellular mechanical microenvironment to regulate stem cell chondrogenesis: Insights from a microgel model

(2020) Qi Feng et al.   Acta Biomaterialia

The vascular architecture of the pancreatic islets: A homage to August Krogh

(2020) Massimo Muratore et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Oxygenation strategies for encapsulated islet and beta cell transplants

(2019) Klearchos K. Papas et al.   ADVANCED DRUG DELIVERY REVIEWS

Insulin Pumps: Review of Technological Advancement in Diabetes Management

(2019) Nicoleta D. Sora et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Injection and Self‐Assembly of Bioinspired Stem Cell‐Laden Gelatin/Hyaluronic Acid Hybrid Microgels Promote Cartilage Repair In Vivo

(2019) Qi Feng et al.   ADVANCED FUNCTIONAL MATERIALS

Engineering “cell-particle hybrids” of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation

(2019) Tiep Tien Nguyen et al.   BIOMATERIALS

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

(2019) Qingsheng Liu et al.   Nature Communications

Developing mechanically robust, triazole-zwitterionic hydrogels to mitigate foreign body response (FBR) for islet encapsulation

(2019) Qingsheng Liu et al.   BIOMATERIALS

Engineering Strategies to Improve Islet Transplantation for Type 1 Diabetes Therapy

(2019) Alisa M. White et al.   ACS Biomaterials-Science & Engineering

Design of a vascularized synthetic poly(ethylene glycol) macroencapsulation device for islet transplantation

(2018) Jessica D. Weaver et al.   BIOMATERIALS

Low-adhesive ethylene vinyl alcohol-based packaging to xenogeneic islet encapsulation for type 1 diabetes treatment

(2018) Kai-Chiang Yang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance

(2018) Devon M. Headen et al.   NATURE MATERIALS

Impact of Oxygen on Pancreatic Islet Survival

(2018) Hirotake Komatsu et al.   PANCREAS

Effect of an oxygen-generating scaffold on the viability and insulin secretion function of porcine neonatal pancreatic cell clusters

(2018) Eun Mi Lee et al.   XENOTRANSPLANTATION

Microporous Polymer Scaffolds for the Transplantation of Embryonic Stem Cell Derived Pancreatic Progenitors to a Clinically Translatable Site for the Treatment of Type I Diabetes

(2018) Tadas Kasputis et al.   ACS Biomaterials-Science & Engineering

Microporous Polymer Scaffolds for the Transplantation of Embryonic Stem Cell Derived Pancreatic Progenitors to a Clinically Translatable Site for the Treatment of Type I Diabetes

(2018) Tadas Kasputis et al.   ACS Biomaterials Science & Engineering

Global trends in diabetes complications: a review of current evidence

(2018) Jessica L. Harding et al.   DIABETOLOGIA

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

(2018) Matthew A. Bochenek et al.   Nature Biomedical Engineering

Extracellular hemoglobin combined with an O2 -generating material overcomes O2 limitation in the bioartificial pancreas

(2018) Anne Mouré et al.   BIOTECHNOLOGY AND BIOENGINEERING

Muted fibrosis from protected islets

(2018) Alexander E. Vlahos et al.   Nature Biomedical Engineering

Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet

(2017) Berit L. Strand et al.   Stem Cells Translational Medicine

Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets

(2016) Jeffrey M.H. Liu et al.   BIOMATERIALS

Clinical pancreatic islet transplantation

(2016) A. M. James Shapiro et al.   Nature Reviews Endocrinology

The changing face of diabetes complications

(2016) Edward W Gregg et al.   Lancet Diabetes & Endocrinology

An Overview of Insulin Pumps and Glucose Sensors for the Generalist

(2016) Brooke McAdams et al.   Journal of Clinical Medicine

Antifibrotic effect of rapamycin containing polyethylene glycol-coated alginate microcapsule in islet xenotransplantation

(2015) Heon-Seok Park et al.   Journal of Tissue Engineering and Regenerative Medicine

Transplantable bioartificial pancreas devices: current status and future prospects

(2015) Barbara Ludwig et al.   LANGENBECKS ARCHIVES OF SURGERY

Microfluidics-generated pancreatic islet microfibers for enhanced immunoprotection

(2013) Yesl Jun et al.   BIOMATERIALS

The Pathogenesis and Natural History of Type 1 Diabetes

(2013) M. A. Atkinson   Cold Spring Harbor Perspectives in Medicine

Insulin Pump Therapy Is Associated with Less Post-Exercise Hyperglycemia than Multiple Daily Injections: An Observational Study of Physically Active Type 1 Diabetes Patients

(2012) Jane E. Yardley et al.   Diabetes Technology & Therapeutics

Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials

(2012) E. Pedraza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perfluorodecalin-enriched fibrin matrix for human islet culture

(2011) Elisa Maillard et al.   BIOMATERIALS

Advancing islet transplantation: from engraftment to the immune response

(2011) R. F. Gibly et al.   DIABETOLOGIA

Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo

(2010) Lara R. Nyman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pancreatic Islet Culture and Preservation Strategies: Advances, Challenges, and Future Outlook

(2010) Jamal Daoud et al.   CELL TRANSPLANTATION

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

Risk factors for islet loss during culture prior to transplantation

(2008) Tatsuya Kin et al.   TRANSPLANT INTERNATIONAL