Transplantation of Islet-Containing microcapsules modified with constitutional isomers of sulfated alginate in diabetic mice to mitigate fibrosis for Long-term glycemic control

A Tough Polysaccharide-based Cell-Laden Double-Network Hydrogel Promotes Articular Cartilage Tissue Regeneration in Rabbits

(2021) Payam Baei et al.   CHEMICAL ENGINEERING JOURNAL

Anti-fatigue, highly resilient photocrosslinkable gellan gum hydrogels reinforced by flexible nanoparticulate polyurethane multi-crosslinkers

(2021) Maryam Sahraro et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

An overview of current advancements in pancreatic islet transplantation into the omentum

(2021) Kimia Damyar et al.   Islets

An injectable and antifouling self-fused supramolecular hydrogel for preventing postoperative and recurrent adhesions

(2020) Xiaoye Zhao et al.   CHEMICAL ENGINEERING JOURNAL

Microencapsulated islet-like microtissues with toroid geometry for enhanced cellular viability

(2019) Yang Chen et al.   Acta Biomaterialia

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

(2019) Qingsheng Liu et al.   Nature Communications

Effect of chemical composition and sulfated modification of alginate in the development of delivery systems based on electrostatic interactions for small molecule drugs

(2019) Zahra Nazemi et al.   MATERIALS LETTERS

Novel Balanced Charged Alginate/PEI Polyelectrolyte Hydrogel that Resists Foreign-Body Reaction

(2018) Jiamin Zhang et al.   ACS Applied Materials & Interfaces

Heparin-Eluting Electrospun Nanofiber Yarns for Antithrombotic Vascular Sutures

(2018) Sooneon Bae et al.   ACS Applied Materials & Interfaces

Facile fabrication of sulfated alginate electrospun nanofibers

(2018) Hamed Daemi et al.   CARBOHYDRATE POLYMERS

Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance

(2018) Devon M. Headen et al.   NATURE MATERIALS

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

(2018) Matthew A. Bochenek et al.   Nature Biomedical Engineering

Advances in functionalizing fucoidans and alginates (bio)polymers by structural modifications: A review

(2018) I.P. Shanura Fernando et al.   CHEMICAL ENGINEERING JOURNAL

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

(2017) Joshua C. Doloff et al.   NATURE MATERIALS

Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet

(2017) Berit L. Strand et al.   Stem Cells Translational Medicine

Sulfated alginate microspheres associate with factor H and dampen the inflammatory cytokine response

(2016) Øystein Arlov et al.   Acta Biomaterialia

The state of the art of islet transplantation and cell therapy in type 1 diabetes

(2016) Silvia Pellegrini et al.   ACTA DIABETOLOGICA

Heparin-Mimicking Polymers: Synthesis and Biological Applications

(2016) Samantha J. Paluck et al.   BIOMACROMOLECULES

Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices

(2016) Shang Song et al.   BIOTECHNOLOGY AND BIOENGINEERING

8. Pharmacologic Approaches to Glycemic Treatment

(2016)   DIABETES CARE

Winner of the student award in the undergraduate category, 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Evaluation of the tissue response to alginate encapsulated islets in an omentum pouch model

(2016) Veronica Ibarra et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

(2016) Arturo J Vegas et al.   NATURE BIOTECHNOLOGY

Advances in islet encapsulation technologies

(2016) Tejal Desai et al.   NATURE REVIEWS DRUG DISCOVERY

Clinical pancreatic islet transplantation

(2016) A. M. James Shapiro et al.   Nature Reviews Endocrinology

Progress in Clinical Encapsulated Islet Xenotransplantation

(2016) David K.C. Cooper et al.   TRANSPLANTATION

Heparin inhibits the inflammatory response induced by LPS and HMGB1 by blocking the binding of HMGB1 to the surface of macrophages

(2015) Li Li et al.   CYTOKINE

THERAPY OF ENDOCRINE DISEASE: Islet transplantation for type 1 diabetes: so close and yet so far away

(2015) Mohsen Khosravi-Maharlooei et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Antidiabetic Activity of Differently Regioselective Chitosan Sulfates in Alloxan-Induced Diabetic Rats

(2015) Ronge Xing et al.   Marine Drugs

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Inducible VEGF Expression by Human Embryonic Stem Cell-Derived Mesenchymal Stromal Cells Reduces the Minimal Islet Mass Required to Reverse Diabetes

(2015) E. Hajizadeh-Saffar et al.   Scientific Reports

Antibacterial Adhesion of Borneol-Based Polymer via Surface Chiral Stereochemistry

(2014) Lingqiong Luo et al.   ACS Applied Materials & Interfaces

Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees

(2014) Øystein Arlov et al.   BIOMACROMOLECULES

Overcoming immunological barriers in regenerative medicine

(2014) Johannes L Zakrzewski et al.   NATURE BIOTECHNOLOGY

Clinical Porcine Islet Xenotransplantation Under Comprehensive Regulation

(2014) S. Matsumoto et al.   TRANSPLANTATION PROCEEDINGS

A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells

(2014) Swapnil V. Bhujbal et al.   Scientific Reports

Anticoagulant Surface Coating Using Composite Polysaccharides with Embedded Heparin-Releasing Mesoporous Silica

(2013) Houliang Wei et al.   ACS Applied Materials & Interfaces

Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications

(2013) Yingkai Liang et al.   Acta Biomaterialia

Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient

(2013) D. Jacobs-Tulleneers-Thevissen et al.   DIABETOLOGIA

Beneficial Effects of Coating Alginate Microcapsules with Macromolecular Heparin Conjugates–In Vitro and In Vivo Study

(2013) Vijayaganapathy Vaithilingam et al.   TISSUE ENGINEERING PART A

Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine

(2012) Bryan N. Brown et al.   BIOMATERIALS

Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts

(2012) James D. Bryers et al.   BIOTECHNOLOGY AND BIOENGINEERING

Modulating Cell Behaviors on Chiral Polymer Brush Films with Different Hydrophobic Side Groups

(2012) Xing Wang et al.   LANGMUIR

Immune Rejection after Pancreatic Islet Cell Transplantation: In Vivo Dual Contrast-enhanced MR Imaging in a Mouse Model

(2012) Ping Wang et al.   RADIOLOGY

Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases

(2011) G. Basta et al.   DIABETES CARE

Biomaterials/Tissue Interactions: Possible Solutions to Overcome Foreign Body Response

(2010) Jacqueline M. Morais et al.   AAPS Journal

Synthesis and anticoagulant activity of sodium alginate sulfates

(2010) Lihong Fan et al.   CARBOHYDRATE POLYMERS

The hypoxia response pathway and β-cell function

(2010) J. Cantley et al.   DIABETES OBESITY & METABOLISM

Effect of Triple Costimulation Blockade on Islet Allograft Survival in Sensitized Mice

(2010) R. Diab et al.   TRANSPLANTATION PROCEEDINGS

Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs

(2009) Limor Baruch et al.   BIOMEDICAL MICRODEVICES

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

In Vivo Selection of Biocompatible Alginates for Islet Encapsulation and Subcutaneous Transplantation

(2009) Sophie Vériter et al.   TISSUE ENGINEERING PART A

The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins

(2008) Inbar Freeman et al.   BIOMATERIALS

Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events

(2008) Marco Guerrini et al.   NATURE BIOTECHNOLOGY

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY