The impact of locally-delivered tacrolimus-releasing microspheres and polyethylene glycol-based islet surface modification on xenogeneic islet survival

Evaluation of a coated blade spray-tandem mass spectrometry assay as a new tool for the determination of immunosuppressive drugs in whole blood

(2020) Daniel A. Rickert et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Local release of NECA (5′-(N-ethylcarboxamido)adenosine) from implantable polymeric sheets for enhanced islet revascularization in extrahepatic transplantation site

(2020) Tiep Tien Nguyen et al.   JOURNAL OF CONTROLLED RELEASE

Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation

(2020) Jesus Paez-Mayorga et al.   BIOMATERIALS

Immunoisolation of pancreatic islets via thin-layer surface modification

(2019) Shiva Pathak et al.   JOURNAL OF CONTROLLED RELEASE

Engineering “cell-particle hybrids” of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation

(2019) Tiep Tien Nguyen et al.   BIOMATERIALS

Pancreatic islets engineered with a FasL protein induce systemic tolerance at the induction phase that evolves into long‐term graft‐localized immune privilege

(2019) Kyle B. Woodward et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Clinical islet transplantation

(2018) Andrew R. Pepper et al.   Current Opinion in Organ Transplantation

Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance

(2018) Devon M. Headen et al.   NATURE MATERIALS

Local injections of tacrolimus-loaded hydrogel reduce systemic immunosuppression-related toxicity in vascularized composite allotransplantation

(2018) Dzhuliya V. Dzhonova et al.   TRANSPLANTATION

Tolerance induction by surface immobilization of Jagged-1 for immunoprotection of pancreatic islets

(2018) Zhila Izadi et al.   BIOMATERIALS

Mechanisms of in vivo release of triamcinolone acetonide from PLGA microspheres

(2017) Amy C. Doty et al.   JOURNAL OF CONTROLLED RELEASE

Controlled dexamethasone delivery via double-walled microspheres to enhance long-term adipose tissue retention

(2017) Arta Kelmendi-Doko et al.   Journal of Tissue Engineering

Hybrid Congregation of Islet Single Cells and Curcumin-Loaded Polymeric Microspheres as an Interventional Strategy to Overcome Apoptosis Associated with Pancreatic Islets Transplantation

(2016) Shiva Pathak et al.   ACS Applied Materials & Interfaces

Dose optimization of tacrolimus for improving survival time of PEGylated islets in a rat-to-mouse xenograft model

(2016) Jee-Heon Jeong et al.   MACROMOLECULAR RESEARCH

Clinical pancreatic islet transplantation

(2016) A. M. James Shapiro et al.   Nature Reviews Endocrinology

Intra-cellular immunosuppressive drugs monitoring: A step forward towards better therapeutic efficacy after organ transplantation?

(2016) A. Capron et al.   PHARMACOLOGICAL RESEARCH

Near-Infrared and Fourier Transform Infrared Chemometric Methods for the Quantification of Crystalline Tacrolimus from Sustained-Release Amorphous Solid Dispersion

(2014) Ziyaur Rahman et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A single localized dose of enzyme-responsive hydrogel improves long-term survival of a vascularized composite allograft

(2014) T. Gajanayake et al.   Science Translational Medicine

Phagocytosis Dynamics Depends on Target Shape

(2013) Debjani Paul et al.   BIOPHYSICAL JOURNAL

Effects of Microparticle Size and Fc Density on Macrophage Phagocytosis

(2013) Patricia Pacheco et al.   PLoS One

The effects of 8-arm-PEG-catechol/heparin shielding system and immunosuppressive drug, FK506 on the survival of intraportally allotransplanted islets

(2012) Bok-Hyeon Im et al.   BIOMATERIALS

Surface camouflage of pancreatic islets using 6-arm-PEG-catechol in combined therapy with tacrolimus and anti-CD154 monoclonal antibody for xenotransplantation

(2011) Jee-Heon Jeong et al.   BIOMATERIALS

Pancreatic Islets Engineered with SA-FasL Protein Establish Robust Localized Tolerance by Inducing Regulatory T Cells in Mice

(2011) E. S. Yolcu et al.   JOURNAL OF IMMUNOLOGY

Phagocytosis of IgG-Coated Polystyrene Beads by Macrophages Induces and Requires High Membrane Order

(2011) Astrid Magenau et al.   TRAFFIC

Co-immobilization of urokinase and thrombomodulin on islet surfaces by poly(ethylene glycol)-conjugated phospholipid

(2010) Hao Chen et al.   JOURNAL OF CONTROLLED RELEASE

Evaluation of in vivo–in vitro release of dexamethasone from PLGA microspheres

(2008) Banu S. Zolnik et al.   JOURNAL OF CONTROLLED RELEASE