- Home
- Publications
- Publication Search
- Publication Details
Title
Progress toward active or passive HIV-1 vaccination
Authors
Keywords
-
Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 214, Issue 1, Pages 3-16
Publisher
Rockefeller University Press
Online
2016-12-23
DOI
10.1084/jem.20161765
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
- (2016) Dennis R. Burton et al. Annual Review of Immunology
- HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant
- (2016) Cassandra A. Simonich et al. CELL
- Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
- (2016) Mattia Bonsignori et al. CELL
- Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies
- (2016) Bryan Briney et al. CELL
- Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice
- (2016) Amelia Escolano et al. CELL
- Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires
- (2016) Ming Tian et al. CELL
- HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies
- (2016) Kwinten Sliepen et al. Expert Review of Vaccines
- HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
- (2016) Jon M. Steichen et al. IMMUNITY
- Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
- (2016) Daniel T. MacLeod et al. IMMUNITY
- Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
- (2016) Jinghe Huang et al. IMMUNITY
- A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
- (2016) Rajeev Gautam et al. NATURE
- Determinants of HIV-1 broadly neutralizing antibody induction
- (2016) Peter Rusert et al. NATURE MEDICINE
- Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques
- (2016) Ann J Hessell et al. NATURE MEDICINE
- Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
- (2016) Harry B Gristick et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Visualizing antibody affinity maturation in germinal centers
- (2016) J. M. J. Tas et al. SCIENCE
- Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice
- (2016) D. Sok et al. SCIENCE
- HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
- (2016) J. G. Jardine et al. SCIENCE
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
- (2016) R. Kong et al. SCIENCE
- Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus
- (2016) Jinyan Liu et al. SCIENCE
- Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages
- (2016) Ruijun Zhang et al. Science Translational Medicine
- Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
- (2016) Andrew T. McGuire et al. Nature Communications
- Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site
- (2016) Harry B Gristick et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells
- (2016) Jidnyasa Ingale et al. Cell Reports
- Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C
- (2016) P. J. Klasse et al. PLoS Pathogens
- Structural basis for germline antibody recognition of HIV-1 immunogens
- (2016) Louise Scharf et al. eLife
- An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
- (2016) Marit J. van Gils et al. Nature Microbiology
- Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes
- (2015) Steven W. de Taeye et al. CELL
- Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
- (2015) Pia Dosenovic et al. CELL
- Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors
- (2015) Tongqing Zhou et al. CELL
- Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1
- (2015) Rachel P. Galimidi et al. CELL
- Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection
- (2015) Xueling Wu et al. CELL
- Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults
- (2015) J. E. Ledgerwood et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans
- (2015) Fernando Garces et al. IMMUNITY
- Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection
- (2015) Kevin O. Saunders et al. JOURNAL OF VIROLOGY
- Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers
- (2015) Javier Guenaga et al. JOURNAL OF VIROLOGY
- Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection
- (2015) Kevin O. Saunders et al. JOURNAL OF VIROLOGY
- Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity
- (2015) Joyce K. Hu et al. JOURNAL OF VIROLOGY
- Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
- (2015) Marina Caskey et al. NATURE
- Antibody responses to envelope glycoproteins in HIV-1 infection
- (2015) Dennis R Burton et al. NATURE IMMUNOLOGY
- Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
- (2015) Jinal N Bhiman et al. NATURE MEDICINE
- Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen
- (2015) J. G. Jardine et al. SCIENCE
- T cell help controls the speed of the cell cycle in germinal center B cells
- (2015) A. D. Gitlin et al. SCIENCE
- Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection
- (2015) Rebecca M. Lynch et al. Science Translational Medicine
- HIV broadly neutralizing antibody targets
- (2015) Constantinos Kurt Wibmer et al. Current Opinion in HIV and AIDS
- Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design
- (2015) Shailendra Kumar Sharma et al. Cell Reports
- Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
- (2014) Ariel Halper-Stromberg et al. CELL
- Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies
- (2014) Fernando Garces et al. CELL
- Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy
- (2014) Anthony P. West et al. CELL
- Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies
- (2014) Thomas B. Kepler et al. Cell Host & Microbe
- Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
- (2014) Masashi Shingai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
- (2014) Nicole A. Doria-Rose et al. NATURE
- Clonal selection in the germinal centre by regulated proliferation and hypermutation
- (2014) Alexander D. Gitlin et al. NATURE
- Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex
- (2014) Devin Sok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
- (2014) A. T. McGuire et al. SCIENCE
- Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
- (2013) Peter Hraber et al. AIDS
- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
- (2013) Florian Klein et al. CELL
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
- (2013) Andrew T. McGuire et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neutralizing antibodies to HIV-1 induced by immunization
- (2013) Laura E. McCoy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B Cells from Knock-in Mice Expressing Broadly Neutralizing HIV Antibody b12 Carry an Innocuous B Cell Receptor Responsive to HIV Vaccine Candidates
- (2013) T. Ota et al. JOURNAL OF IMMUNOLOGY
- Immune Tolerance Negatively Regulates B Cells in Knock-In Mice Expressing Broadly Neutralizing HIV Antibody 4E10
- (2013) C. Doyle-Cooper et al. JOURNAL OF IMMUNOLOGY
- Antibody and Antiretroviral Preexposure Prophylaxis Prevent Cervicovaginal HIV-1 Infection in a Transgenic Mouse Model
- (2013) H. Gruell et al. JOURNAL OF VIROLOGY
- Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia
- (2013) Masashi Shingai et al. NATURE
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
- (2013) Hua-Xin Liao et al. NATURE
- Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine
- (2013) Scott M. Hammer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization
- (2013) I. S. Georgiev et al. SCIENCE
- Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer
- (2013) J.-P. Julien et al. SCIENCE
- Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
- (2013) D. Lyumkis et al. SCIENCE
- Antibodies in HIV-1 Vaccine Development and Therapy
- (2013) F. Klein et al. SCIENCE
- Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
- (2013) J. Jardine et al. SCIENCE
- Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs
- (2013) Sam Hoot et al. PLoS Pathogens
- The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
- (2013) Devin Sok et al. PLoS Pathogens
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Germinal Centers
- (2012) Gabriel D. Victora et al. Annual Review of Immunology
- Chromosome Translocation, B Cell Lymphoma, and Activation-Induced Cytidine Deaminase
- (2012) Davide F. Robbiani et al. Annual Review of Pathology-Mechanisms of Disease
- Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies
- (2012) Peter D. Kwong et al. IMMUNITY
- Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovirus HIV Vaccine (Step Study)
- (2012) A. Duerr et al. JOURNAL OF INFECTIOUS DISEASES
- Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
- (2012) D. C. Montefiori et al. JOURNAL OF INFECTIOUS DISEASES
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
- (2012) Barton F Haynes et al. NATURE BIOTECHNOLOGY
- A mouse model for HIV-1 entry
- (2012) J. Pietzsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
- (2012) B. Moldt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
- (2012) Anthony P. West et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
- (2012) H. Mouquet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B Cells in 2F5 VH x VL Knockin Mice Reveals Multiple Tolerance Controls
- (2011) L. Verkoczy et al. JOURNAL OF IMMUNOLOGY
- Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
- (2011) M. Bonsignori et al. JOURNAL OF VIROLOGY
- The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
- (2011) E. S. Gray et al. JOURNAL OF VIROLOGY
- Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study
- (2011) Glenda E Gray et al. LANCET INFECTIOUS DISEASES
- Antibody-based protection against HIV infection by vectored immunoprophylaxis
- (2011) Alejandro B. Balazs et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease
- (2011) Felix Breden et al. PLoS One
- Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
- (2011) Javier Guenaga et al. PLoS One
- Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design
- (2011) R. Diskin et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter
- (2010) Gabriel D. Victora et al. CELL
- Anti-gp41 Antibodies Cloned from HIV-Infected Patients with Broadly Neutralizing Serologic Activity
- (2010) J. Pietzsch et al. JOURNAL OF VIROLOGY
- Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1
- (2010) M. Pancera et al. JOURNAL OF VIROLOGY
- Therapeutic antibodies, vaccines and antibodyomes
- (2010) Dimiter S. Dimitrov mAbs
- Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
- (2010) Hugo Mouquet et al. NATURE
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: Implications for evasion of immune responses and design of vaccine immunogens
- (2009) Xiaodong Xiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cloning and expression of murine Ig genes from single B cells
- (2009) Thomas Tiller et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization
- (2009) P. Dosenovic et al. JOURNAL OF IMMUNOLOGY
- Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
- (2009) A. J. Hessell et al. JOURNAL OF VIROLOGY
- Human Immunodeficiency Virus Type 1 Elite Neutralizers: Individuals with Broad and Potent Neutralizing Activity Identified by Using a High-Throughput Neutralization Assay together with an Analytical Selection Algorithm
- (2009) M. D. Simek et al. JOURNAL OF VIROLOGY
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
- (2009) Leonidas Stamatatos et al. NATURE MEDICINE
- Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
- (2009) Ann J Hessell et al. NATURE MEDICINE
- Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand
- (2009) Supachai Rerks-Ngarm et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
- (2009) L. Verkoczy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
- (2009) Ann J. Hessell et al. PLoS Pathogens
- A method for identification of HIV gp140 binding memory B cells in human blood
- (2008) Johannes F. Scheid et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies
- (2008) N. A. Doria-Rose et al. JOURNAL OF VIROLOGY
- Human Immunodeficiency Virus Type 1 Env Trimer Immunization of Macaques and Impact of Priming with Viral Vector or Stabilized Core Protein
- (2008) A. Morner et al. JOURNAL OF VIROLOGY
- Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection
- (2008) D. N. Sather et al. JOURNAL OF VIROLOGY
- Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
- (2008) J. M. Binley et al. JOURNAL OF VIROLOGY
- Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
- (2008) Y. Li et al. JOURNAL OF VIROLOGY
- Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
- (2008) Susan P Buchbinder et al. LANCET
- Correlates of antibody-mediated protection against HIV infection
- (2008) Quentin Sattentau Current Opinion in HIV and AIDS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now