Alcohol-Induced Oxidative Stress and the Role of Antioxidants in Alcohol Use Disorder: A Systematic Review

Disrupted H2S Signaling by Cigarette Smoking and Alcohol Drinking: Evidence from Cellular, Animal, and Clinical Studies

(2021) Ethan Read et al.   Antioxidants

Carnitine in Alcohol Use Disorders: A Scoping Review

(2021) A. Brianne Bota et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice

(2021) Hong Xu et al.   Frontiers in Pharmacology

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

(2021) Matthew J Page et al.   BMJ-British Medical Journal

The Aldehyde Dehydrogenase ALDH2*2 Allele, Associated with Alcohol Drinking Behavior, Dates Back to Prehistoric Times

(2021) Chih-Lang Lin et al.   Biomolecules

BXD Recombinant Inbred Mice as a Model to Study Neurotoxicity

(2021) Airton C. Martins et al.   Biomolecules

Exploring the Role of Alcohol Metabolizing Genotypes in a 12-Week Clinical Trial of Naltrexone for Alcohol Use Disorder

(2021) João M. Castaldelli-Maia et al.   Biomolecules

Oxidative Stress Inhibition by Resveratrol in Alcohol Dependent Mice

(2020) Carla Petrella et al.   NUTRITION

Alcohol Use Disorder and Risk of Suicide in a Swedish Population-Based Cohort

(2020) Alexis C. Edwards et al.   AMERICAN JOURNAL OF PSYCHIATRY

Brain-derived neurotrophic factor and glutathione peroxidase as state biomarkers in alcohol use disorder patients undergoing detoxification

(2020) Shu-Yu Wu et al.   MEDICINE

Evaluation of oxidative stress biomarkers and liver and renal functional parameters in patients during treatment a mental health unit to treat alcohol dependence

(2020) Samuel Selbach Dries et al.   DRUG AND CHEMICAL TOXICOLOGY

Alcohol Use Disorder, Neurodegeneration, Alzheimer’s and Parkinson’s Disease: Interplay Between Oxidative Stress, Neuroimmune Response and Excitotoxicity

(2020) Haziq Kamal et al.   Frontiers in Cellular Neuroscience

The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses

(2020) Wenqianglong Li et al.   PSYCHIATRIC GENETICS

Meta-Analysis on Associations of Alcohol Metabolism Genes With Alcohol Use Disorder in East Asians

(2019) Michelle J Zaso et al.   ALCOHOL AND ALCOHOLISM

Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count, and individual criteria

(2019) Dongbing Lai et al.   GENES BRAIN AND BEHAVIOR

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

(2019) Henry R. Kranzler et al.   Nature Communications

Therapeutic Prospects of Cannabidiol for Alcohol Use Disorder and Alcohol-Related Damages on the Liver and the Brain

(2019) Julia De Ternay et al.   Frontiers in Pharmacology

Brain-behavior relations and effects of aging and common comorbidities in alcohol use disorder: A review.

(2019) Edith V. Sullivan et al.   NEUROPSYCHOLOGY

On the Neurobiological Role of Oxidative Stress in Alcohol-Induced Impulsive, Aggressive and Suicidal Behavior

(2019) Tobore Onojighofia Tobore   SUBSTANCE USE & MISUSE

Telomere Biology in Mood Disorders: An Updated, Comprehensive Review of the Literature

(2019) Ather Muneer et al.   Clinical Psychopharmacology and Neuroscience

Tetrahydrobiopterin restores microvascular dysfunction in young adult binge drinkers

(2019) Chueh‐Lung Hwang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Aldehyde dehydrogenase-2 as a therapeutic target

(2019) Mitsuru Kimura et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison

(2019) Yan Sun et al.   Translational Psychiatry

Evaluation of polymorphisms in repair and detoxification genes in alcohol drinkers and non‐drinkers using capillary electrophoresis

(2019) Caroline Oliveira de Araújo Melo et al.   ELECTROPHORESIS

Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking

(2019) Adrien Guillot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetaldehyde induces phosphorylation of dynamin-related protein 1 and mitochondrial dysfunction via elevating intracellular ROS and Ca2+ levels

(2019) Tingting Yan et al.   Redox Biology

Global statistics on alcohol, tobacco and illicit drug use: 2017 status report

(2018) Amy Peacock et al.   ADDICTION

Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population

(2018) Joel Gelernter et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Elevated monoamine oxidase A activity and protein levels in rodent brain during acute withdrawal after chronic intermittent ethanol vapor exposure

(2018) Brittany A. Matthews et al.   DRUG AND ALCOHOL DEPENDENCE

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Max G Griswold et al.   LANCET

Neurometabolite Levels in Alcohol Use Disorder Patients During Baclofen Treatment and Prediction of Relapse to Heavy Drinking

(2018) Kirsten C. Morley et al.   Frontiers in Psychiatry

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

(2018) Raymond K. Walters et al.   NATURE NEUROSCIENCE

Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats: A dual mechanism?

(2018) Mario Rivera-Meza et al.   NEUROPHARMACOLOGY

Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde

(2018) Naruhisa Yamaki et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis

(2017) Jennifer L. Steiner et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

DNA damage and oxidative stress induced by seizures are decreased by anticonvulsant and neuroprotective effects of lobeline, a candidate to treat alcoholism

(2017) Liana Dantas da Costa e Silva et al.   METABOLIC BRAIN DISEASE

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study

(2017) E Jorgenson et al.   MOLECULAR PSYCHIATRY

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

Olive polyphenol effects in a mouse model of chronic ethanol addiction

(2017) Valentina Carito et al.   NUTRITION

Telomere length in alcohol dependence: A role for impulsive choice and childhood maltreatment

(2017) Jee In Kang et al.   PSYCHONEUROENDOCRINOLOGY

A Systems Approach Implicates a Brain Mitochondrial Oxidative Homeostasis Co-expression Network in Genetic Vulnerability to Alcohol Withdrawal

(2017) Nicole A. R. Walter et al.   Frontiers in Genetics

Oxidoreductive homeostasis in alcohol-dependent male patients and the risk of alcohol drinking relapse in a 6-month follow-up

(2016) Jacek Budzyński et al.   ALCOHOL

Overview of the Genetics of Alcohol Use Disorder

(2016) Elisabeth A. Tawa et al.   ALCOHOL AND ALCOHOLISM

Up-Regulation of PKR Signaling Pathway by Ethanol Displays an Age of Onset-Dependent Relationship

(2016) Jeremy W. Duncan et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Comparative investigation of antioxidant activity of human serum blood by amperometric, voltammetric and chemiluminescent methods

(2016) Evgenii Plotnikov et al.   Archives of Medical Science

Carbonated soft drinks induce oxidative stress and alter the expression of certain genes in the brains of Wistar rats

(2016) ADEL EL-TERRAS et al.   Molecular Medicine Reports

Binge ethanol exposure increases the Krüppel-like factor 11-monoamine oxidase (MAO) pathway in rats: Examining the use of MAO inhibitors to prevent ethanol-induced brain injury

(2016) Jeremy W. Duncan et al.   NEUROPHARMACOLOGY

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans

(2015) Ke Xu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Molecular Links between Alcohol and Tobacco Induced DNA Damage, Gene Polymorphisms and Patho-physiological Consequences: A Systematic Review of Hepatic Carcinogenesis

(2015) Abdul Anvesh Mansoori et al.   Asian Pacific Journal of Cancer Prevention

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects

(2014) A. Plemenitas et al.   ALCOHOL AND ALCOHOLISM

Comparison of Oxidative DNA Damage Between Alcohol-Dependent Patients With and Without Delirium Tremens

(2014) Ming-Chyi Huang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Glutathione and redox signaling in substance abuse

(2014) Joachim D. Uys et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities

(2014) Che-Hong Chen et al.   PHYSIOLOGICAL REVIEWS

Differential Sensitivity of Prefrontal Cortex and Hippocampus to Alcohol-Induced Toxicity

(2014) Anna-Kate Fowler et al.   PLoS One

The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies

(2014) B. Verhulst et al.   PSYCHOLOGICAL MEDICINE

Alcoholism: A systemic proinflammatory condition

(2014) Emilio González-Reimers   WORLD JOURNAL OF GASTROENTEROLOGY

Genome-wide DNA methylation analysis in alcohol dependence

(2013) Ruiling Zhang et al.   ADDICTION BIOLOGY

Oxidative damage in young alcohol drinkers: A preliminary study

(2013) Adela Rendón-Ramírez et al.   ALCOHOL

Cyclic Adenosine Monophosphate and Brain-Derived Neurotrophic Factor Decreased Oxidative Stress and Apoptosis in Developing Hypothalamic Neuronal Cells: Role of Microglia

(2013) Nadka I. Boyadjieva et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Alpha-Lipoic Acid Reduces Ethanol Self-Administration in Rats

(2013) Alessandra T. Peana et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Reduction in Central H2O2Levels Prevents Voluntary Ethanol Intake in Mice: A Role for the Brain Catalase-H2O2System in Alcohol Binge Drinking

(2013) Juan Carlos Ledesma et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

ALDH2is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural chinese sample

(2013) Ellen E. Quillen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genome-wide DNA methylation patterns in discordant sib pairs with alcohol dependence

(2013) Rongrong Zhao et al.   Asia-Pacific Psychiatry

Greater Monoamine Oxidase A Binding in Alcohol Dependence

(2013) Brittany A. Matthews et al.   BIOLOGICAL PSYCHIATRY

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication

(2013) Byung Lae Park et al.   HUMAN GENETICS

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

(2013) J Gelernter et al.   MOLECULAR PSYCHIATRY

Replication of Genome Wide Association Studies of Alcohol Dependence: Support for Association with Variation in ADH1C

(2013) Joanna M. Biernacka et al.   PLoS One

The effects of acute ethanol exposure and ageing on rat brain glutathione metabolism

(2012) Michela Sommavilla et al.   FREE RADICAL RESEARCH

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

(2012) Liya Qin et al.   Journal of Neuroinflammation

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

(2011) Josef Frank et al.   ADDICTION BIOLOGY

Effects of Alcohol on Histone Deacetylase 2 (HDAC2) and the Neuroprotective Role of Trichostatin A (TSA)

(2011) Marisela Agudelo et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Relationship Between Liver Function and Brain Shrinkage in Patients with Alcohol Dependence

(2011) Chun-Hsin Chen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Strong Association of the Alcohol Dehydrogenase 1B Gene (ADH1B) with Alcohol Dependence and Alcohol-Induced Medical Diseases

(2011) Dawei Li et al.   BIOLOGICAL PSYCHIATRY

Effects of chronic alcohol consumption on expression levels of APP and Aβ-producing enzymes

(2011) Sae-Rom Kim et al.   BMB Reports

Confirmation of ALDH2 as a Major Locus of Drinking Behavior and of Its Variants Regulating Multiple Metabolic Phenotypes in a Japanese Population

(2011) Fumihiko Takeuchi et al.   CIRCULATION JOURNAL

Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians

(2011) Dawei Li et al.   HUMAN GENETICS

Shortened telomeres in individuals with abuse in alcohol consumption

(2011) Sofia Pavanello et al.   INTERNATIONAL JOURNAL OF CANCER

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

(2011) L J Bierut et al.   MOLECULAR PSYCHIATRY

Increased Oxidative DNA Damage in Patients With Alcohol Dependence and Its Correlation With Alcohol Withdrawal Severity

(2010) Chun-Hsin Chen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Oxidative stress in anxiety and comorbid disorders

(2010) Iiris Hovatta et al.   NEUROSCIENCE RESEARCH

Cellular and Mitochondrial Effects of Alcohol Consumption

(2010) Salvador Manzo-Avalos et al.   International Journal of Environmental Research and Public Health

Effects of N-acetylcysteine on alcohol abstinence and alcohol-induced adverse effects in rats

(2009) Fábio Rodrigues Ferreira Seiva et al.   ALCOHOL

Associations and Interactions Between SNPs in the Alcohol Metabolizing Genes and Alcoholism Phenotypes in European Americans

(2009) Richard Sherva et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Genome-wide Association Study of Alcohol Dependence

(2009) Jens Treutlein et al.   ARCHIVES OF GENERAL PSYCHIATRY

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo

(2009) Andrew J. Birley et al.   HUMAN MOLECULAR GENETICS

Gene–environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population

(2009) Miyuki Tsuchihashi-Makaya et al.   HYPERTENSION RESEARCH

An investigation of associations between alcohol use disorder and polymorphisms onALDH2,BDNF,5-HTTLPR, andMTHFRgenes in older Korean men

(2009) Sangmoon Shin et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Alterations in Oxidative Stress Status During Early Alcohol Withdrawal in Alcoholic Patients

(2009) Ming-Chyi Huang et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Alcohol-use disorders

(2009) Marc A Schuckit   LANCET

Mechanism of alcohol-induced oxidative stress and neuronal injury

(2008) James Haorah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis

(2008) Stuart Macgregor et al.   HUMAN MOLECULAR GENETICS

The correlation between early alcohol withdrawal severity and oxidative stress in patients with alcohol dependence

(2008) Ming-Chyi Huang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

(2008) Che-Hong Chen et al.   SCIENCE