Overview of the Genetics of Alcohol Use Disorder

Epidemiology ofDSM-5Drug Use Disorder

(2016) Bridget F. Grant et al.   JAMA Psychiatry

Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence

(2015) Rohan H. C. Palmer et al.   ADDICTION

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Whole genome/exome sequencing in mood and psychotic disorders

(2014) Tadafumi Kato   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Contribution of Excessive Alcohol Consumption to Deaths and Years of Potential Life Lost in the United States

(2014) Mandy Stahre et al.   Preventing Chronic Disease

ALDH2is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural chinese sample

(2013) Ellen E. Quillen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Three Mutually Informative Ways to Understand the Genetic Relationships Among Behavioral Disinhibition, Alcohol Use, Drug Use, Nicotine Use/Dependence, and Their Co-occurrence: Twin Biometry, GCTA, and Genome-Wide Scoring

(2013) Scott I. Vrieze et al.   BEHAVIOR GENETICS

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication

(2013) Byung Lae Park et al.   HUMAN GENETICS

Genetics of bipolar disorder

(2013) Nick Craddock et al.   LANCET

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

(2013) J Gelernter et al.   MOLECULAR PSYCHIATRY

Role of Oxygen Holes inLixCoO2Revealed by Soft X-Ray Spectroscopy

(2013) T. Mizokawa et al.   PHYSICAL REVIEW LETTERS

Replication of Genome Wide Association Studies of Alcohol Dependence: Support for Association with Variation in ADH1C

(2013) Joanna M. Biernacka et al.   PLoS One

Genome-Wide Significant Association Signals inIPO11-HTR1ARegion Specific for Alcohol and Nicotine Codependence

(2012) Lingjun Zuo et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence

(2012) Lingjun Zuo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence

(2012) Joanna M. Biernacka et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53

(2012) J-C Wang et al.   MOLECULAR PSYCHIATRY

Recent advances in the genetic epidemiology and molecular genetics of substance use disorders

(2012) Kenneth S Kendler et al.   NATURE NEUROSCIENCE

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

(2011) Josef Frank et al.   ADDICTION BIOLOGY

Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men

(2011) Inkyung Baik et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Confirmation of ALDH2 as a Major Locus of Drinking Behavior and of Its Variants Regulating Multiple Metabolic Phenotypes in a Japanese Population

(2011) Fumihiko Takeuchi et al.   CIRCULATION JOURNAL

Insight from genome-wide association studies in rheumatoid arthritis and multiple sclerosis

(2011) Akari Suzuki et al.   FEBS LETTERS

Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians

(2011) Dawei Li et al.   HUMAN GENETICS

Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: Evidence from the current studies

(2011) Dingyan Chen et al.   JOURNAL OF AFFECTIVE DISORDERS

A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence

(2011) Ke-Sheng Wang et al.   JOURNAL OF PSYCHIATRIC RESEARCH

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

(2011) L J Bierut et al.   MOLECULAR PSYCHIATRY

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q

(2011) Lingjun Zuo et al.   NEUROPSYCHOPHARMACOLOGY

A Novel, Functional and Replicable Risk Gene Region for Alcohol Dependence Identified by Genome-Wide Association Study

(2011) Lingjun Zuo et al.   PLoS One

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

(2011) G. Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Suggestion of Roles for Both Common and Rare Risk Variants in Genome-wide Studies of Schizophrenia

(2010) Michael J. Owen et al.   ARCHIVES OF GENERAL PSYCHIATRY

The serotonin transporter gene and risk for alcohol dependence: A meta-analytic review

(2010) R. Kathryn McHugh et al.   DRUG AND ALCOHOL DEPENDENCE

GWAS: heritability missing in action?

(2010) Angus J Clarke et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

(2010) H. J. Williams et al.   HUMAN MOLECULAR GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

A genome-wide association study of alcohol dependence

(2010) L. J. Bierut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic influences of dopamine transport gene on alcohol dependence: A pooled analysis of 13 studies with 2483 cases and 1753 controls

(2010) Mingqing Xu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The role of early life stress as a predictor for alcohol and drug dependence

(2010) Mary-Anne Enoch   PSYCHOPHARMACOLOGY

A Genomewide Association Study of Nicotine and Alcohol Dependence in Australian and Dutch Populations

(2010) Penelope A Lind et al.   Twin Research and Human Genetics

Association of Markers in the 3′ Region of the GluR5 Kainate Receptor Subunit Gene to Alcohol Dependence

(2009) Henry R. Kranzler et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Genome-wide Association Study of Alcohol Dependence

(2009) Jens Treutlein et al.   ARCHIVES OF GENERAL PSYCHIATRY

Are there genetic influences on addiction: evidence from family, adoption and twin studies

(2008) Arpana Agrawal et al.   ADDICTION

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

(2008) V Moskvina et al.   MOLECULAR PSYCHIATRY

Whole-genome association study of bipolar disorder

(2008) P Sklar et al.   MOLECULAR PSYCHIATRY

A framework for interpreting genome-wide association studies of psychiatric disorders

(2008)   MOLECULAR PSYCHIATRY

Large recurrent microdeletions associated with schizophrenia

(2008) Hreinn Stefansson et al.   NATURE

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE