Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 51, Pages 25974-25981
Publisher
Proceedings of the National Academy of Sciences
Online
2019-12-03
DOI
10.1073/pnas.1908137116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study
- (2019) Gyongyi Szabo et al. HEPATOLOGY
- ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA enriched extracellular vesicles
- (2019) Wonhyo Seo et al. JOURNAL OF HEPATOLOGY
- Aldehyde dehydrogenase 2 in the spotlight: The link between mitochondria and neurodegeneration
- (2018) Romina Deza-Ponzio et al. NEUROTOXICOLOGY
- Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update
- (2018) Arnau Panisello-Roselló et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study
- (2018) Elliot B Tapper et al. BMJ-British Medical Journal
- Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study
- (2018) Elliot B Tapper et al. BMJ-British Medical Journal
- Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids
- (2018) Yanhang Gao et al. GUT
- Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2018) Max G Griswold et al. LANCET
- Alcohol Use in Patients with Chronic Liver Disease
- (2018) Daniel Fuster et al. NEW ENGLAND JOURNAL OF MEDICINE
- Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review
- (2018) Howard J. Edenberg et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Diagnosis and Treatment of Alcohol Use Disorder in Patients With End-Stage Alcoholic Liver Disease
- (2018) Fabio Caputo et al. HEPATOLOGY
- AAV Gene Therapy for Alcoholism: Inhibition of Mitochondrial Aldehyde Dehydrogenase Enzyme Expression in Hepatoma Cells
- (2017) Anamaria C. Sanchez et al. HUMAN GENE THERAPY
- The role of neuroimmune signaling in alcoholism
- (2017) Fulton T. Crews et al. NEUROPHARMACOLOGY
- Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC
- (2017) Lauren MacDonagh et al. Oncotarget
- Alda-1 Attenuates Lung Ischemia-Reperfusion Injury by Reducing 4-Hydroxy-2-Nonenal in Alveolar Epithelial Cells
- (2016) Jie Ding et al. CRITICAL CARE MEDICINE
- Acamprosate: A Review of Its Use in Alcohol Dependence
- (2015) Greg L. Plosker DRUGS
- Ethanol and Acetaldehyde After Intraperitoneal Administration to Aldh2-Knockout Mice-Reflection in Blood and Brain Levels
- (2015) Mostofa Jamal et al. NEUROCHEMICAL RESEARCH
- Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice
- (2014) Hyo-Jung Kwon et al. HEPATOLOGY
- Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities
- (2014) Che-Hong Chen et al. PHYSIOLOGICAL REVIEWS
- Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis
- (2014) Marilyn D. Skinner et al. PLoS One
- Cytochrome P450-activated prodrugs
- (2013) Paul R Ortiz de Montellano Future Medicinal Chemistry
- The role of the opioid system in alcohol dependence
- (2013) David J Nutt JOURNAL OF PSYCHOPHARMACOLOGY
- Alda-1 reduces cerebral ischemia/reperfusion injury in rat through clearance of reactive aldehydes
- (2013) Si-Hai Fu et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Aldehyde dehydrogenase inhibition generates a reactive dopamine metabolite autotoxic to dopamine neurons
- (2013) Jonathan A. Doorn et al. PARKINSONISM & RELATED DISORDERS
- Differences in Susceptibility to Inactivation of Human Aldehyde Dehydrogenases by Lipid Peroxidation Byproducts
- (2012) Belem Yoval-Sánchez et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Drug targeting to the diseased liver
- (2012) Klaas Poelstra et al. JOURNAL OF CONTROLLED RELEASE
- The Efficacy of Disulfiram for the Treatment of Alcohol Use Disorder
- (2011) Charlotte H. Jørgensen et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
- (2011) Frédéric Langevin et al. NATURE
- Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
- (2010) Samantha Perez-Miller et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNA interference against aldehyde dehydrogenase-2: development of tools for alcohol research
- (2009) Gabriel Cortínez et al. ALCOHOL
- Suppression of Heavy Drinking and Alcohol Seeking by a Selective ALDH-2 Inhibitor
- (2009) Maria P. Arolfo et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Pharmacokinetic and pharmacodynamic basis for overcoming acetaldehyde-induced adverse reaction in Asian alcoholics, heterozygous for the variant ALDH2*2 gene allele
- (2009) Yi-Chyan Chen et al. Pharmacogenetics and Genomics
- The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption
- (2009) Philip J Brooks et al. PLOS MEDICINE
- The safety of disulfiram for the treatment of alcohol and cocaine dependence in randomized clinical trials: guidance for clinical practice
- (2008) Robert Malcolm et al. Expert Opinion On Drug Safety
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started