Reactive Oxygen Species-Mediated Activation of AMP-Activated Protein Kinase and c-Jun N-terminal Kinase Plays a Critical Role in Beta-Sitosterol-Induced Apoptosis in Multiple Myeloma U266 cells

Proteasome inhibitor bortezomib overcomes P-gp-mediated multidrug resistance in resistant leukemic cell lines

(2011) B. ZHENG et al.   International Journal of Laboratory Hematology

Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells

(2011) Jang Choon Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting MAGE-C1/CT7 Expression Increases Cell Sensitivity to the Proteasome Inhibitor Bortezomib in Multiple Myeloma Cell Lines

(2011) Fabricio de Carvalho et al.   PLoS One

ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells

(2010) Siddik Sarkar et al.   CANCER BIOLOGY & THERAPY

p38 MAPK and NF-κB pathways are involved in naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells

(2010) Chien-Chih Chiu et al.   CANCER LETTERS

Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells

(2010) Sun-Hee Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells

(2010) Ying-Jung Chen et al.   TOXICON

Green Tea Catechin Controls Apoptosis in Colon Cancer Cells by Attenuation of H2O2-Stimulated COX-2 Expression via the AMPK Signaling Pathway at Low-Dose H2O2

(2009) In-Ja Park et al.   Annals of the New York Academy of Sciences

Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism

(2009) Shinichi Ota et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

(2009) S. Fogarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

(2009) Dong-Oh Moon et al.   CANCER LETTERS

Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway

(2009) Xiao-hong Cao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

COX-2, VEGF and tumour angiogenesis

(2009) D.P. Toomey et al.   SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND

Cytotoxic and apoptotic effects of single and mixed oxides of β-sitosterol on HepG2-cells

(2009) K. Koschutnig et al.   TOXICOLOGY IN VITRO

Involvement of caspase and MAPK activities in norcantharidin-induced colorectal cancer cell apoptosis

(2009) Pei-Yu Yang et al.   TOXICOLOGY IN VITRO

Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model

(2008) Sirwan M. Hadad et al.   BREAST CANCER RESEARCH AND TREATMENT

Hispolon induces apoptosis in human gastric cancer cells through a ROS-mediated mitochondrial pathway

(2008) Wei Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE