Three-dimensional structure of kinetochore-fibers in human mitotic spindles

Self-organization of kinetochore-fibers in human mitotic spindles

(2022) William Conway et al.   eLife

Mechanical Mechanisms of Chromosome Segregation

(2021) Maya I. Anjur-Dietrich et al.   Cells

Semi‐automatic stitching of filamentous structures in image stacks from serial‐section electron tomography

(2021) Norbert Lindow et al.   JOURNAL OF MICROSCOPY

K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

(2021) Marcus A. Begley et al.   MOLECULAR BIOLOGY OF THE CELL

The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation

(2020) Kseniya Ustinova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

(2020) David P. Hoffman et al.   SCIENCE

Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure

(2020) Alexandra F. Long et al.   JOURNAL OF CELL BIOLOGY

Male meiotic spindle features that efficiently segregate paired and lagging chromosomes

(2020) Gunar Fabig et al.   eLife

Active forces shape the metaphase spindle through a mechanical instability

(2020) David Oriola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mechanics of Mitotic Cell Rounding

(2020) Anna V. Taubenberger et al.   Frontiers in Cell and Developmental Biology

Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

(2020) Reza Farhadifar et al.   eLife

Central spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

(2019) Che-Hang Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner

(2019) Jonathan Kuhn et al.   JOURNAL OF CELL BIOLOGY

Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase

(2019) Eileen O'Toole et al.   MOLECULAR BIOLOGY OF THE CELL

The Physics of the Metaphase Spindle

(2018) David Oriola et al.   Annual Review of Biophysics

Chromosome Segregation Is Biased by Kinetochore Size

(2018) Danica Drpic et al.   CURRENT BIOLOGY

Cooperative Accumulation of Dynein-Dynactin at Microtubule Minus-Ends Drives Microtubule Network Reorganization

(2018) Ruensern Tan et al.   DEVELOPMENTAL CELL

A Switch in Microtubule Orientation during C. elegans Meiosis

(2018) Stefanie Redemann et al.   CURRENT BIOLOGY

The kinetochore–microtubule interface at a glance

(2018) Julie K. Monda et al.   JOURNAL OF CELL SCIENCE

γ-Tubulin–γ-Tubulin Interactions as the Basis for the Formation of a Meshwork

(2018) Catalina Rosselló et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis

(2017) Faye M. Nixon et al.   JOURNAL OF CELL SCIENCE

Automated tilt series alignment and tomographic reconstruction in IMOD

(2017) David N. Mastronarde et al.   JOURNAL OF STRUCTURAL BIOLOGY

Mitotic spindle assembly in animal cells: a fine balancing act

(2017) Suzanna L. Prosser et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

C. elegans chromosomes connect to centrosomes by anchoring into the spindle network

(2017) Stefanie Redemann et al.   Nature Communications

A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation

(2016) Maxim I. Molodtsov et al.   CELL

Tau excess impairs mitosis and kinesin-5 function, leading to aneuploidy and cell death

(2016) Anne-Laure Bougé et al.   Disease Models & Mechanisms

PRC1‐labeled microtubule bundles and kinetochore pairs show one‐to‐one association in metaphase

(2016) Bruno Polak et al.   EMBO REPORTS

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

(2016) Elizabeth H. Kellogg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores

(2016) Janko Kajtez et al.   Nature Communications

Measuring Pushing and Braking Forces Generated by Ensembles of Kinesin-5 Crosslinking Two Microtubules

(2015) Yuta Shimamoto et al.   DEVELOPMENTAL CELL

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle

(2015) Faye M Nixon et al.   eLife

Direct kinetochore–spindle pole connections are not required for chromosome segregation

(2014) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis

(2014) Kristina M. Godek et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physical basis of spindle self-organization

(2014) Jan Brugués et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved and divergent features of kinetochores and spindle microtubule ends from five species

(2013) J. Richard McIntosh et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Structural Basis for Microtubule Binding and Release by Dynein

(2012) W. B. Redwine et al.   SCIENCE

Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos

(2011) Britta Weber et al.   JOURNAL OF STRUCTURAL BIOLOGY

Kinesin-5, a mitotic microtubule-associated motor protein, modulates neuronal migration

(2011) Aditi Falnikar et al.   MOLECULAR BIOLOGY OF THE CELL

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Force and Length in the Mitotic Spindle

(2009) Sophie Dumont et al.   CURRENT BIOLOGY