The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle

TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation

(2015) C. Gutierrez-Caballero et al.   Biology Open

The dynamic spindle matrix

(2014) Nina Schweizer et al.   CURRENT OPINION IN CELL BIOLOGY

Direct kinetochore–spindle pole connections are not required for chromosome segregation

(2014) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Presynaptic Clathrin Levels Are a Limiting Factor for Synaptic Transmission

(2014) F. J. Lopez-Murcia et al.   JOURNAL OF NEUROSCIENCE

Mechanical design principles of a mitotic spindle

(2014) Jonathan J Ward et al.   eLife

CHD4 Is a RanGTP-Dependent MAP that Stabilizes Microtubules and Regulates Bipolar Spindle Formation

(2013) Hideki Yokoyama et al.   CURRENT BIOLOGY

Cryo-electron tomography: The challenge of doing structural biology in situ

(2013) Vladan Lučić et al.   JOURNAL OF CELL BIOLOGY

Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding

(2013) Fiona E. Hood et al.   JOURNAL OF CELL BIOLOGY

Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension

(2013) L. P. Cheeseman et al.   JOURNAL OF CELL SCIENCE

Aurora A kinase (AURKA) in normal and pathological cell division

(2012) Anna S. Nikonova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oncogenic FGFR3 gene fusions in bladder cancer

(2012) Sarah V. Williams et al.   HUMAN MOLECULAR GENETICS

A nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosis

(2012) Changfu Yao et al.   MOLECULAR BIOLOGY OF THE CELL

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

(2012) D. Singh et al.   SCIENCE

Do nuclear envelope and intranuclear proteins reorganize during mitosis to form an elastic, hydrogel-like spindle matrix?

(2011) Kristen M. Johansen et al.   CHROMOSOME RESEARCH

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

(2011) Daniel G Booth et al.   EMBO JOURNAL

Directly probing the mechanical properties of the spindle and its matrix

(2010) Jesse C. Gatlin et al.   JOURNAL OF CELL BIOLOGY

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

(2010) Chiou-Hong Lin et al.   JOURNAL OF CELL BIOLOGY

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

(2010) Nina C. Hubner et al.   JOURNAL OF CELL BIOLOGY

Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment

(2010) W. Fu et al.   JOURNAL OF CELL SCIENCE

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program

(2010) S Schmidt et al.   ONCOGENE

Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability

(2009) Samuel F. Bakhoum et al.   CURRENT BIOLOGY

Requirement for Nudel and dynein for assembly of the lamin B spindle matrix

(2009) Li Ma et al.   NATURE CELL BIOLOGY

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL

Structural and regulatory roles of nonmotor spindle proteins

(2008) Amity L Manning et al.   CURRENT OPINION IN CELL BIOLOGY