Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure

Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes

(2020) Pooja Suresh et al.   eLife

Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle

(2019) Jun Takagi et al.   DEVELOPMENTAL CELL

The mammalian kinetochore–microtubule interface: robust mechanics and computation with many microtubules

(2019) Alexandra F Long et al.   CURRENT OPINION IN CELL BIOLOGY

The Physics of the Metaphase Spindle

(2018) David Oriola et al.   Annual Review of Biophysics

Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism

(2018) Shivangi Agarwal et al.   JOURNAL OF CELL BIOLOGY

The kinetochore–microtubule interface at a glance

(2018) Julie K. Monda et al.   JOURNAL OF CELL SCIENCE

The Spindle: Integrating Architecture and Mechanics across Scales

(2018) Mary Williard Elting et al.   TRENDS IN CELL BIOLOGY

Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

(2018) Tae Yeon Yoo et al.   eLife

Microtubule-severing enzymes: From cellular functions to molecular mechanism

(2018) Francis J. McNally et al.   JOURNAL OF CELL BIOLOGY

Micromanipulation of Chromosomes in Insect Spermatocytes

(2018) Nicolas K.H. Lin et al.   Jove-Journal of Visualized Experiments

Autoregulation and repair in microtubule homeostasis

(2018) Ivana Gasic et al.   CURRENT OPINION IN CELL BIOLOGY

Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment

(2017) Philip Auckland et al.   JOURNAL OF CELL BIOLOGY

Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation

(2017) Joshua Guild et al.   MOLECULAR BIOLOGY OF THE CELL

Direct measurement of the strength of microtubule attachment to yeast centrosomes

(2017) Kimberly K. Fong et al.   MOLECULAR BIOLOGY OF THE CELL

Tubulin acetylation protects long-lived microtubules against mechanical ageing

(2017) Didier Portran et al.   NATURE CELL BIOLOGY

A Comparative Analysis of Spindle Morphometrics across Metazoans

(2015) Marina E. Crowder et al.   CURRENT BIOLOGY

Microtubules self-repair in response to mechanical stress

(2015) Laura Schaedel et al.   NATURE MATERIALS

Draft De Novo Transcriptome of the Rat Kangaroo Potorous tridactylus as a Tool for Cell Biology

(2015) Dylan B. Udy et al.   PLoS One

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Direct kinetochore–spindle pole connections are not required for chromosome segregation

(2014) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Force on spindle microtubule minus ends moves chromosomes

(2014) Mary Williard Elting et al.   JOURNAL OF CELL BIOLOGY

Catch and release: how do kinetochores hook the right microtubules during mitosis?

(2014) Krishna K. Sarangapani et al.   TRENDS IN GENETICS

Mechanical design principles of a mitotic spindle

(2014) Jonathan J Ward et al.   eLife

Regulation of Chromosome Speeds in Mitosis

(2013) M. D. Betterton et al.   Cellular and Molecular Bioengineering

Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells

(2013) Gul Civelekoglu-Scholey et al.   JOURNAL OF CELL BIOLOGY

Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanisms

(2013) K. K. Sarangapani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The coupling between sister kinetochore directional instability and oscillations in centromere stretch in metaphase PtK1 cells

(2012) Xiaohu Wan et al.   MOLECULAR BIOLOGY OF THE CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Microneedle-based analysis of the micromechanics of the metaphase spindle assembled in Xenopus laevis egg extracts

(2012) Yuta Shimamoto et al.   Nature Protocols

Targeted axon-attached recording with fluorescent patch-clamp pipettes in brain slices

(2012) Takuya Sasaki et al.   Nature Protocols

Deformations Within Moving Kinetochores Reveal Different Sites of Active and Passive Force Generation

(2012) S. Dumont et al.   SCIENCE

Kinetochores and disease: keeping microtubule dynamics in check!

(2011) Samuel F Bakhoum et al.   CURRENT OPINION IN CELL BIOLOGY

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

(2010) Khuloud Jaqaman et al.   JOURNAL OF CELL BIOLOGY

Directly probing the mechanical properties of the spindle and its matrix

(2010) Jesse C. Gatlin et al.   JOURNAL OF CELL BIOLOGY

Tension directly stabilizes reconstituted kinetochore-microtubule attachments

(2010) Bungo Akiyoshi et al.   NATURE

Compression Regulates Mitotic Spindle Length by a Mechanochemical Switch at the Poles

(2009) Sophie Dumont et al.   CURRENT BIOLOGY

Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores

(2009) Irina Matos et al.   JOURNAL OF CELL BIOLOGY

Probing the mechanical architecture of the vertebrate meiotic spindle

(2009) Takeshi Itabashi et al.   NATURE METHODS

Molecular architecture of the kinetochore–microtubule interface

(2007) Iain M. Cheeseman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY