K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

KIF15 Promotes Proliferation and Growth of Hepatocellular Carcinoma

(2020) Yue-Feng Sun et al.   Analytical Cellular Pathology

Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes

(2020) Pooja Suresh et al.   eLife

KIF15 promotes bladder cancer proliferation via the MEK–ERK signaling pathway

(2019) Hongda Zhao et al.   Cancer Management and Research

Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15

(2019) Heidi L.H. Malaby et al.   JOURNAL OF CELL BIOLOGY

KIF15 plays a role in promoting the tumorigenicity of melanoma

(2019) Xiaoyu Yu et al.   EXPERIMENTAL EYE RESEARCH

Kif15 functions as an active mechanical ratchet

(2018) Toni McHugh et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule dynamics: an interplay of biochemistry and mechanics

(2018) Gary J. Brouhard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics

(2018) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Spindle: Integrating Architecture and Mechanics across Scales

(2018) Mary Williard Elting et al.   TRENDS IN CELL BIOLOGY

Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes

(2018) Megan E. Dumas et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics

(2017) Barbara J. Mann et al.   MOLECULAR BIOLOGY OF THE CELL

NuMA recruits dynein activity to microtubule minus-ends at mitosis

(2017) Christina L Hueschen et al.   eLife

Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores

(2016) Janko Kajtez et al.   Nature Communications

Draft De Novo Transcriptome of the Rat Kangaroo Potorous tridactylus as a Tool for Cell Biology

(2015) Dylan B. Udy et al.   PLoS One

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle

(2015) Faye M Nixon et al.   eLife

Kinesin-12 Kif15 Targets Kinetochore Fibers through an Intrinsic Two-Step Mechanism

(2014) Emma G. Sturgill et al.   CURRENT BIOLOGY

Direct kinetochore–spindle pole connections are not required for chromosome segregation

(2014) Vitali Sikirzhytski et al.   JOURNAL OF CELL BIOLOGY

Force on spindle microtubule minus ends moves chromosomes

(2014) Mary Williard Elting et al.   JOURNAL OF CELL BIOLOGY

Kinetochore-microtubule stability governs the metaphase requirement for Eg5

(2014) A. Sophia Gayek et al.   MOLECULAR BIOLOGY OF THE CELL

Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance

(2014) Hoi Tang Ma et al.   Molecular Oncology

The Kinesin-12 Kif15 is a processive track-switching tetramer

(2014) Hauke Drechsler et al.   eLife

Kinesin-12 Differentially Affects Spindle Assembly Depending on Its Microtubule Substrate

(2013) Emma G. Sturgill et al.   CURRENT BIOLOGY

The role of actin and myosin in PtK2 spindle length changes induced by laser microbeam irradiations across the spindle

(2013) Rozhan Sheykhani et al.   Cytoskeleton

Nonautonomous Movement of Chromosomes in Mitosis

(2013) Elina Vladimirou et al.   DEVELOPMENTAL CELL

Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension

(2013) L. P. Cheeseman et al.   JOURNAL OF CELL SCIENCE

Nucleation and Transport Organize Microtubules in Metaphase Spindles

(2012) Jan Brugués et al.   CELL

Maturation of the kinetochore-microtubule interface and the meaning of metaphase

(2012) António J. Pereira et al.   CHROMOSOME RESEARCH

Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation

(2012) Jonne A Raaijmakers et al.   EMBO JOURNAL

HURP Regulates Chromosome Congression by Modulating Kinesin Kif18A Function

(2011) Fan Ye et al.   CURRENT BIOLOGY

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

(2011) Daniel G Booth et al.   EMBO JOURNAL

Regulation of microtubule dynamics by kinesins

(2011) Douglas R. Drummond   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly

(2009) Marvin E. Tanenbaum et al.   CURRENT BIOLOGY

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

(2008) Alexander W. Bird et al.   JOURNAL OF CELL BIOLOGY