Tau excess impairs mitosis and kinesin-5 function, leading to aneuploidy and cell death

Specific interaction of KIF11 with ZBP1 regulates the transport of  -actin mRNA and cell motility

(2015) T. Song et al.   JOURNAL OF CELL SCIENCE

Connecting the dots between tau dysfunction and neurodegeneration

(2015) Bess Frost et al.   TRENDS IN CELL BIOLOGY

Tau co-organizes dynamic microtubule and actin networks

(2015) Auréliane Elie et al.   Scientific Reports

Expression of 1N3R-Tau Isoform Inhibits Cell Proliferation by Inducing S Phase Arrest in N2a Cells

(2015) Li Li et al.   PLoS One

The structure and function of actin cytoskeleton in mature glutamatergic dendritic spines

(2014) Alba Bellot et al.   BRAIN RESEARCH

The C-Terminus of Tau Protein Plays an Important Role in Its Stability and Toxicity

(2014) Junhua Geng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function

(2014) Csilla Ari et al.   NEUROBIOLOGY OF AGING

X chromosome aneuploidy in the Alzheimer’s disease brain

(2014) Yuri B Yurov et al.   Molecular Cytogenetics

Epithelial junctions maintain tissue architecture by directing planar spindle orientation

(2013) Yu-ichiro Nakajima et al.   NATURE

Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

(2013) Giacomina Rossi et al.   NEUROGENETICS

Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3 

(2013) G. Povellato et al.   Biology Open

Aneuploid Cells Are Differentially Susceptible to Caspase-Mediated Death during Embryonic Cerebral Cortical Development

(2012) S. E. Peterson et al.   JOURNAL OF NEUROSCIENCE

Alzheimer Aβ disrupts the mitotic spindle and directly inhibits mitotic microtubule motors

(2011) Sergiy I. Borysov et al.   CELL CYCLE

Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation

(2011) Surendra S. Ambegaokar et al.   HUMAN MOLECULAR GENETICS

TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

(2011) Nan Ma et al.   JOURNAL OF CELL BIOLOGY

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

Selective Cell Death of Hyperploid Neurons in Alzheimer’s Disease

(2010) Thomas Arendt et al.   AMERICAN JOURNAL OF PATHOLOGY

Monte Carlo Simulations of Tau Proteins: Effect of Phosphorylation

(2010) Y.S. Jho et al.   BIOPHYSICAL JOURNAL

A new function of microtubule-associated protein tau: Involvement in chromosome stability

(2010) Giacomina Rossi et al.   CELL CYCLE

Association between variants in IDE-KIF11-HHEX and plasma amyloid β levels

(2010) Christiane Reitz et al.   NEUROBIOLOGY OF AGING

Inhibition of Kinesin-5, a Microtubule-Based Motor Protein, As a Strategy for Enhancing Regeneration of Adult Axons

(2010) Shen Lin et al.   TRAFFIC

Alzheimer Aβ Peptide Induces Chromosome Mis-Segregation and Aneuploidy, Including Trisomy 21: Requirement for Tau and APP

(2009) Antoneta Granic et al.   MOLECULAR BIOLOGY OF THE CELL

Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning

(2009) Ivan Y. Iourov et al.   NEUROBIOLOGY OF DISEASE

Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model

(2008) Shreyasi Chatterjee et al.   HUMAN MOLECULAR GENETICS

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE

Alzheimer's presenilin 1 causes chromosome missegregation and aneuploidy

(2006) Debrah I. Boeras et al.   NEUROBIOLOGY OF AGING