Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32

The Damage-Associated Molecular Patterns (DAMPs) as Potential Targets to Treat Osteoarthritis: Perspectives From a Review of the Literature

(2021) Cécile Lambert et al.   Frontiers in Medicine

TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis

(2021) Joana Ferreira-Gomes et al.   Journal of Pain Research

Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis

(2020) S.A. Ali et al.   OSTEOARTHRITIS AND CARTILAGE

Parthenolide promotes the repair of spinal cord injury by modulating M1/M2 polarization via the NF-κB and STAT 1/3 signaling pathway

(2020) Tao Gaojian et al.   Cell Death Discovery

Osteoarthritis year in review: genetics, genomics, epigenetics

(2020) A. Ratneswaran et al.   OSTEOARTHRITIS AND CARTILAGE

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

(2019) Rodrigo Coutinho de Almeida et al.   ANNALS OF THE RHEUMATIC DISEASES

PTX3: an inflammatory protein modulating ultrastructure and bioenergetics of human endothelial cells

(2019) Albino Carrizzo et al.   Immunity & Ageing

Quercetin reduces TNF‐α‐induced mesangial cell proliferation and inhibits PTX3 production: Involvement of NF‐κB signaling pathway

(2019) Yue Liu et al.   PHYTOTHERAPY RESEARCH

NF-B Signaling Pathways in Osteoarthritic Cartilage Destruction

(2019) Choi et al.   Cells

Association between Bone marrow lesions & synovitis and symptoms in symptomatic knee osteoarthritis

(2019) T.A. Perry et al.   OSTEOARTHRITIS AND CARTILAGE

Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2

(2018) Haiyan Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Redox and NF-κB signaling in osteoarthritis

(2018) Panagiotis Lepetsos et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-224 inhibition prevents progression of cervical carcinoma by targeting PTX3

(2018) Li-Mei Yu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is “Inflammation” Always Inflammation?

(2016) Onkar P. Kulkarni et al.   MEDIATORS OF INFLAMMATION

Pentraxin 3 Is Closely Associated With Tubulointerstitial Injury in Lupus Nephritis

(2016) Yun Pang et al.   MEDICINE

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

(2016) William H. Robinson et al.   Nature Reviews Rheumatology

Direct in vivo evidence of activated macrophages in human osteoarthritis

(2016) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

Pentraxin 3 in serum and synovial fluid of patients with rheumatoid arthritis with and without autoantibodies

(2016) T Weitoft et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The Dual Complexity of PTX3 in Health and Disease: A Balancing Act?

(2016) Elena Magrini et al.   TRENDS IN MOLECULAR MEDICINE

Monocyte MicroRNA Expression in Active Systemic Juvenile Idiopathic Arthritis Implicates MicroRNA-125a-5p in Polarized Monocyte Phenotypes

(2016) Grant S. Schulert et al.   Arthritis & Rheumatology

Sucrose non-fermenting AMPK related kinase/Pentraxin 3 and DNA damage axis: a gateway to cardiovascular disease in systemic lupus erythematosus among Egyptian patients

(2016) Doaa Hussein Zineldeen et al.   ANNALS OF CLINICAL BIOCHEMISTRY

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

(2015) Eduardo Bonavita et al.   CELL

Pentraxin 3 Induces Vascular Endothelial Dysfunction Through a P-selectin/Matrix Metalloproteinase-1 Pathway

(2015) A. Carrizzo et al.   CIRCULATION

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

Strategies for the prevention of knee osteoarthritis

(2015) Ewa M. Roos et al.   Nature Reviews Rheumatology

Arthritic and non-arthritic synovial fluids modulate IL10 and IL1RA gene expression in differentially activated primary human monocytes

(2015) S. Lopa et al.   OSTEOARTHRITIS AND CARTILAGE

Synovitis in knee osteoarthritis: a precursor of disease?

(2014) I Atukorala et al.   ANNALS OF THE RHEUMATIC DISEASES

microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation

(2014) A. Rudnicki et al.   HUMAN MOLECULAR GENETICS

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

(2013) Carmela R Balistreri et al.   Immunity & Ageing

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

(2013) Jeremy Sokolove et al.   Therapeutic Advances in Musculoskeletal Disease

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Lifetime Risk and Age at Diagnosis of Symptomatic Knee Osteoarthritis in the US

(2012) Elena Losina et al.   ARTHRITIS CARE & RESEARCH

Quantitative magnetic resonance imaging evidence of synovial proliferation is associated with radiographic severity of knee osteoarthritis

(2011) Svetlana Krasnokutsky et al.   ARTHRITIS AND RHEUMATISM

NF-κB in immunobiology

(2011) Matthew S Hayden et al.   CELL RESEARCH

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

Role of complement and Fc  receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

(2010) F. Moalli et al.   BLOOD

Evolution of the Pentraxin Family: The New Entry PTX4

(2010) Y. Martinez de la Torre et al.   JOURNAL OF IMMUNOLOGY

Rolling back neutrophil adhesion

(2010) Rodger P McEver   NATURE IMMUNOLOGY

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Pentraxin 3 in unstable angina and non-ST-segment elevation myocardial infarction

(2009) Shigeru Matsui et al.   ATHEROSCLEROSIS

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial Infarction

(2008) Monica Salio et al.   CIRCULATION

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

(2008) Carla R Scanzello et al.   CURRENT OPINION IN RHEUMATOLOGY

Structural recognition and functional activation of FcγR by innate pentraxins

(2008) Jinghua Lu et al.   NATURE