NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Markers of oxidant stress that are clinically relevant in aging and age-related disease

(2013) Kimberly D. Jacob et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Toll like receptor signaling in “inflammaging”: microRNA as new players

(2013) Fabiola Olivieri et al.   Immunity & Ageing

Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway

(2012) Wei Huang et al.   ACTA PHARMACOLOGICA SINICA

Caloric restriction may reverse age-related autonomic decline in humans

(2012) Phyllis K. Stein et al.   AGING CELL

The caloric restriction paradigm: Implications for healthy human aging

(2012) Rozalyn M. Anderson et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells

(2012) Yu Jin Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Possible role of NF-κB in hormesis during ageing

(2012) S. Chirumbolo   BIOGERONTOLOGY

Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock

(2012) Thomas A. Rando et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

 Forever young? Exploring the link between rapamycin, longevity and cancer

(2012) Michael Van Meter et al.   CELL CYCLE

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

(2012) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondria and Cardiovascular Aging

(2012) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Sirtuins: NAD+-dependent deacetylase mechanism and regulation

(2012) Anthony A Sauve et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mitochondrial respiratory chain dysfunction: Implications in neurodegeneration

(2012) María Morán et al.   FREE RADICAL BIOLOGY AND MEDICINE

NF-κB: where did it come from and why?

(2012) Thomas D. Gilmore et al.   IMMUNOLOGICAL REVIEWS

Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice

(2012) R. Strong et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Curcumin induces permanent growth arrest of human colon cancer cells: Link between senescence and autophagy

(2012) Grazyna Mosieniak et al.   MECHANISMS OF AGEING AND DEVELOPMENT

TNFα regulates the localization of CD40 in lipid rafts of glioma cells

(2012) Richa Tewari et al.   MOLECULAR BIOLOGY REPORTS

Curcuminoid Binding to Embryonal Carcinoma Cells: Reductive Metabolism, Induction of Apoptosis, Senescence, and Inhibition of Cell Proliferation

(2012) Wolfgang W. Quitschke   PLoS One

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

(2011) Antero Salminen et al.   CELLULAR SIGNALLING

Plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via NF-kappaB in rats

(2011) Borna Relja et al.   EUROPEAN JOURNAL OF NUTRITION

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Manifestations and mechanisms of stem cell aging

(2011) Ling Liu et al.   JOURNAL OF CELL BIOLOGY

SIRT1 and SIRT5 activity expression and behavioral responses to calorie restriction

(2011) Yi-Qun Geng et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intracellular Lipid Flux and Membrane Microdomains as Organizing Principles in Inflammatory Cell Signaling

(2011) M. B. Fessler et al.   JOURNAL OF IMMUNOLOGY

LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: Biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects

(2011) Carmela Rita Balistreri et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells

(2011) E Crescenzi et al.   ONCOGENE

Activation of nuclear factor-kappa B signalling promotes cellular senescence

(2011) E Rovillain et al.   ONCOGENE

The Sterile Inflammatory Response

(2010) Kenneth L. Rock et al.   Annual Review of Immunology

Inflammation, genetic background and longevity

(2010) Giuseppina Candore et al.   BIOGERONTOLOGY

The Promise of Slow Down Ageing May Come from Curcumin

(2010) E. Sikora et al.   CURRENT PHARMACEUTICAL DESIGN

Biomarkers of ageing: A challenge for the future

(2010) Andreas Simm et al.   EXPERIMENTAL GERONTOLOGY

The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation

(2010) C.E. Ash et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Genetics vs. entropy: Longevity factors suppress the NF-κB-driven entropic aging process

(2009) Antero Salminen et al.   AGEING RESEARCH REVIEWS

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Reactive oxygen species-dependent signaling regulates cancer

(2009) Frank Weinberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The JUPITER Trial

(2009) Paul M Ridker  

Biomarkers of aging and disease: Introduction and definitions

(2009) Richard L. Sprott   EXPERIMENTAL GERONTOLOGY

TLR4 Polymorphisms and Ageing: Implications for the Pathophysiology of Age-Related Diseases

(2009) Carmela Rita Balistreri et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The Effect of Age on the Association Between Blood Pressure and Cognitive Function Later in Life

(2009) Sjoerd M. Euser et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Genetic determinants of ageing processes and diseases in later life

(2009) Clare V. Bostock et al.   MATURITAS

INSULIN REGULATES CYTOKINES AND INTERCELLULAR ADHESION MOLECULE-1 GENE EXPRESSION THROUGH NUCLEAR FACTOR-κB ACTIVATION IN LPS-INDUCED ACUTE LUNG INJURY IN RATS

(2009) Joilson O. Martins et al.   SHOCK

NEMO shuttle: A link between DNA damage and NF-κB activation in progeroid syndromes?

(2008) Antero Salminen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diet and Aging

(2008) Matthew D.W. Piper et al.   Cell Metabolism

Poly(ADP-ribose) polymerase activity in different pathologies – The link to inflammation and infarction

(2008) Sascha Beneke   EXPERIMENTAL GERONTOLOGY

A systematic look at an old problem

(2008) Thomas B. L. Kirkwood   NATURE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Immunosenescence and Anti-Immunosenescence Therapies: The Case of Probiotics

(2008) Giuseppina Candore et al.   REJUVENATION RESEARCH