Radicals Scavenging MOFs Enabling Targeting Delivery of siRNA for Rheumatoid Arthritis Therapy

Intrinsic Radical Species Scavenging Activities of Tea Polyphenols Nanoparticles Block Pyroptosis in Endotoxin-Induced Sepsis

(2022) Yuan Chen et al.   ACS Nano

Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA

(2021) Xuemei Ge et al.   Frontiers in Pharmacology

Nanoemulsions Target to Ectopic Lymphoids in Inflamed Joints to Restore Immune Tolerance in Rheumatoid Arthritis

(2021) Chenglong Li et al.   NANO LETTERS

Core Role of Hydrophobic Core of Polymeric Nanomicelle in Endosomal Escape of siRNA

(2021) Chunhui Li et al.   NANO LETTERS

Magnesium-Based Micromotors as Hydrogen Generators for Precise Rheumatoid Arthritis Therapy

(2021) Cong Xu et al.   NANO LETTERS

Non-viral nanoparticles for RNA interference: Principles of design and practical guidelines

(2021) Zehua Liu et al.   ADVANCED DRUG DELIVERY REVIEWS

Albumin mediated reactive oxygen species scavenging and targeted delivery of methotrexate for rheumatoid arthritis therapy

(2021) Jing Zhong et al.   Nano Research

Macrophage-targeted nanomedicine for chronic diseases immunotherapy

(2021) Yuejia Song et al.   CHINESE CHEMICAL LETTERS

Recent Advances in Metal‐Phenolic Networks for Cancer Theranostics

(2021) Zhan Zhang et al.   Small

A cyclic nano-reactor achieving enhanced photodynamic tumor therapy by reversing multiple resistances

(2021) Peng Liu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Macrophages: The Good, the Bad, and the Gluttony

(2021) Ewan A. Ross et al.   Frontiers in Immunology

Anti‐PD‐L1 DNAzyme Loaded Photothermal Mn 2+ /Fe 3+ Hybrid Metal‐Phenolic Networks for Cyclically Amplified Tumor Ferroptosis‐Immunotherapy

(2021) Peng Liu et al.   Advanced Healthcare Materials

Reactive oxygen species and immune regulation

(2020) Zhou Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Ultrasmall Rhodium Nanozyme with RONS Scavenging and Photothermal Activities for Anti-Inflammation and Antitumor Theranostics of Colon Diseases

(2020) Zhaohua Miao et al.   NANO LETTERS

Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles

(2020) Jia Zhuang et al.   Science Advances

ROS-Activatable siRNA-Engineered Polyplex for NIR-Triggered Synergistic Cancer Treatment

(2020) Mengjie Zhang et al.   ACS Applied Materials & Interfaces

Sustainable Nanosheet Antioxidants for Sepsis Therapy via Scavenging Intracellular Reactive Oxygen and Nitrogen Species

(2020) DaBin Yim et al.   ACS Nano

Metal‐Phenolic Networks Nanoplatform to Mimic Antioxidant Defense System for Broad‐Spectrum Radical Eliminating and Endotoxemia Treatment

(2020) Zhiwei Wei et al.   ADVANCED FUNCTIONAL MATERIALS

Core–Shell Nanosystems for Self-Activated Drug–Gene Combinations against Triple-Negative Breast Cancer

(2020) Peng Liu et al.   ACS Applied Materials & Interfaces

Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization

(2020) Yihua Yang et al.   BIOMATERIALS

Targeted Combination of Antioxidative and Anti‐Inflammatory Therapy of Rheumatoid Arthritis using Multifunctional Dendrimer‐Entrapped Gold Nanoparticles as a Platform

(2020) Jin Li et al.   Small

Oxygen‐Enriched Metal‐Phenolic X‐Ray Nanoprocessor for Cancer Radio‐Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy

(2020) Wei Sang et al.   Advanced Science

Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy

(2020) Lina Guo et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic Oxygen Generation and Reactive Oxygen Species Scavenging by Manganese Ferrite/Ceria Co-decorated Nanoparticles for Rheumatoid Arthritis Treatment

(2019) Jonghoon Kim et al.   ACS Nano

Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy

(2019) Lu Liu et al.   ACS Nano

Incorporation of biomolecules in Metal-Organic Frameworks for advanced applications

(2019) Hongde An et al.   COORDINATION CHEMISTRY REVIEWS

Lipidoid-siRNA Nanoparticle-Mediated IL-1β Gene Silencing for Systemic Arthritis Therapy in a Mouse Model

(2019) Ping Song et al.   MOLECULAR THERAPY

Dex-Aco coating simultaneously increase the biocompatibility and transfection efficiency of cationic polymeric gene vectors

(2019) Peng-Fei Cui et al.   JOURNAL OF CONTROLLED RELEASE

Carbogenic Nanozyme with Ultrahigh Reactive Nitrogen Species Selectivity for Traumatic Brain Injury

(2019) Xiaoyu Mu et al.   NANO LETTERS

Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework-8 (ZIF-8)

(2019) Arpita Poddar et al.   Small

Lipidoid-polymer hybrid nanoparticles loaded with TNF siRNA suppress inflammation after intra-articular administration in a murine experimental arthritis model

(2019) Manon A.A. Jansen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Copper Tannic Acid Coordination Nanosheet: A Potent Nanozyme for Scavenging ROS from Cigarette Smoke

(2019) Shichao Lin et al.   Small

A Highly Porous Metal-Organic Framework System to Deliver Payloads for Gene Knockdown

(2019) Michelle H. Teplensky et al.   Chem

Metal–Phenolic Coatings as a Platform to Trigger Endosomal Escape of Nanoparticles

(2019) Jingqu Chen et al.   ACS Nano

Macrophages with regulatory functions, a possible new therapeutic perspective in autoimmune diseases

(2019) Paola Di Benedetto et al.   AUTOIMMUNITY REVIEWS

Metal-organic frameworks for multimodal bioimaging and synergistic cancer chemotherapy

(2019) Zhan Zhang et al.   COORDINATION CHEMISTRY REVIEWS

Oxygen-Self-Supplying and HIF-1α-Inhibiting Core–Shell Nanosystem for Hypoxia-Resistant Photodynamic Therapy

(2019) Peng Liu et al.   ACS Applied Materials & Interfaces

Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases

(2019) Wei He et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanomedicine – advantages for their use in rheumatoid arthritis theranostics

(2019) Shuyi Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Metal Ion/Tannic Acid Assembly as a Versatile Photothermal Platform in Engineering Multimodal Nanotheranostics for Advanced Applications

(2018) Tao Liu et al.   ACS Nano

Oxidative stress in autoimmune rheumatic diseases

(2018) Miranda J. Smallwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism

(2018) Anusha Angajala et al.   Frontiers in Immunology

Rheumatoid arthritis

(2018) Josef S. Smolen et al.   Nature Reviews Disease Primers

Diagnosis and Management of Rheumatoid Arthritis

(2018) Daniel Aletaha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles

(2018) Ruixiang Li et al.   NANO LETTERS

Metal-Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery

(2018) Wen Cai et al.   Advanced Science

Nanotherapeutics relieve rheumatoid arthritis

(2017) Modi Yang et al.   JOURNAL OF CONTROLLED RELEASE

Exploiting passive nanomedicine accumulation at sites of enhanced vascular permeability for non-cancerous applications

(2017) Mikhail Durymanov et al.   JOURNAL OF CONTROLLED RELEASE

Intra-Articular Injections of Polyphenols Protect Articular Cartilage from Inflammation-Induced Degradation: Suggesting a Potential Role in Cartilage Therapeutics

(2015) Venkatachalam Natarajan et al.   PLoS One

Anti-TNF therapy: past, present and future

(2014) C. Monaco et al.   INTERNATIONAL IMMUNOLOGY

Development of macromolecular prodrug for rheumatoid arthritis

(2012) Fang Yuan et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor necrosis factor

(2012) Wen-Ming Chu   CANCER LETTERS

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aberrant Reactive Oxygen and Nitrogen Species Generation in Rheumatoid Arthritis (RA): Causes and Consequences for Immune Function, Cell Survival, and Therapeutic Intervention

(2009) Darren C. Phillips et al.   ANTIOXIDANTS & REDOX SIGNALING