Aberrant Reactive Oxygen and Nitrogen Species Generation in Rheumatoid Arthritis (RA): Causes and Consequences for Immune Function, Cell Survival, and Therapeutic Intervention

Proteasome Inhibitors Enhance TRAIL-Induced Apoptosis through the Intronic Regulation of DR5: Involvement of NF- B and Reactive Oxygen Species-Mediated p53 Activation

(2014) J.-J. Chen et al.   JOURNAL OF IMMUNOLOGY

The tumour suppressor gene p53 modulates the severity of antigen-induced arthritis and the systemic immune response

(2010) M. Leech et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

(2008) Masuko Ushio-Fukai   ANTIOXIDANTS & REDOX SIGNALING

Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?

(2008) Helen R. Griffiths   AUTOIMMUNITY REVIEWS

Involvement of thioredoxin reductase 1 in the regulation of redox balance and viability of rheumatoid synovial cells

(2008) Yukihito Kabuyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic aspects of inflammation and cancer

(2008) Georgina L. Hold et al.   BIOCHEMICAL JOURNAL

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

The dark side of a tumor suppressor: anti-apoptotic p53

(2008) R U Jänicke et al.   CELL DEATH AND DIFFERENTIATION

Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival

(2008) E Giannoni et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial depolarisation and oxidative stress in rheumatoid arthritis patients

(2008) Devapragasan Moodley et al.   CLINICAL BIOCHEMISTRY

Antioxidant intervention in rheumatoid arthritis: results of an open pilot study

(2008) Richard M. van Vugt et al.   CLINICAL RHEUMATOLOGY

Concepts of activated T cell death

(2008) Dirk Brenner et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Small Molecule Bcl-2 Antagonists as Targeted Therapy in Oncology

(2008) Matthew Warr et al.   Current Oncology

Molecular aspects of rheumatoid arthritis: role of environmental factors

(2008) Shu Kobayashi et al.   FEBS Journal

Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax☆

(2008) N BLATT et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitric oxide production of T lymphocytes is increased in rheumatoid arthritis

(2008) György Nagy et al.   IMMUNOLOGY LETTERS

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

(2008) Sébastien Conus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selection against PUMA Gene Expression in Myc-Driven B-Cell Lymphomagenesis

(2008) S. P. Garrison et al.   MOLECULAR AND CELLULAR BIOLOGY

Pro-survival effects of repetitive low-grade oxidative stress are inhibited by simultaneous exposure to Resveratrol

(2008) P CHAKRABORTY et al.   PHARMACOLOGICAL RESEARCH

Signalling, inflammation and arthritis: Crossed signals: the role of interleukin (IL)-12, -17, -23 and -27 in autoimmunity

(2008) V. Paunovic et al.   RHEUMATOLOGY

Consequence of neo-antigenicity of the 'altered self'

(2008) P. Eggleton et al.   RHEUMATOLOGY

Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid

(2008) S. H. Wong et al.   RHEUMATOLOGY

Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate

(2007) M Schiff et al.   ANNALS OF THE RHEUMATIC DISEASES

Phospholipid chlorohydrin induces leukocyte adhesion to ApoE−/− mouse arteries via upregulation of P-selectin

(2007) Gary J. Dever et al.   FREE RADICAL BIOLOGY AND MEDICINE

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY