Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission
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Title
Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission
Authors
Keywords
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Journal
Nature Reviews Rheumatology
Volume 18, Issue 7, Pages 384-397
Publisher
Springer Science and Business Media LLC
Online
2022-06-07
DOI
10.1038/s41584-022-00790-8
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Note: Only part of the references are listed.- miR-155-overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T-cell activation
- (2022) Anton M Olsson et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages
- (2022) Supriya Murthy et al. Cell Death & Disease
- SLAMF7 engagement superactivates macrophages in acute and chronic inflammation
- (2022) Daimon P. Simmons et al. Science Immunology
- Novel insights into macrophage diversity in rheumatoid arthritis synovium
- (2021) Marie-Astrid Boutet et al. AUTOIMMUNITY REVIEWS
- Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
- (2021) Frances Humby et al. LANCET
- Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation
- (2021) Qi-Quan Huang et al. Science Advances
- Origins, Biology, and Diseases of Tissue Macrophages
- (2021) Nehemiah Cox et al. Annual Review of Immunology
- IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation
- (2021) Fan Zhang et al. Genome Medicine
- Synovial tissue derived characteristics are included in a nomogram for the prediction of treatment response in naïve Rheumatoid Arthritis
- (2021) Stefano Alivernini et al. Arthritis & Rheumatology
- Mitochondria as Key Players in the Pathogenesis and Treatment of Rheumatoid Arthritis
- (2021) Sally A. Clayton et al. Frontiers in Immunology
- Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid
- (2021) Nicole Yager et al. ANNALS OF THE RHEUMATIC DISEASES
- Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
- (2021) Kevin Mulder et al. IMMUNITY
- Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs
- (2021) Georg Schett et al. NEW ENGLAND JOURNAL OF MEDICINE
- COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes
- (2021) Lucy MacDonald et al. JCI Insight
- EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update
- (2020) Josef S Smolen et al. ANNALS OF THE RHEUMATIC DISEASES
- Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection
- (2020) Helena Aegerter et al. NATURE IMMUNOLOGY
- Notch signalling drives synovial fibroblast identity and arthritis pathology
- (2020) Kevin Wei et al. NATURE
- A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients
- (2020) Alessandra Nerviani et al. Frontiers in Immunology
- Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties
- (2020) Basak B. Ural et al. Science Immunology
- Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
- (2020) Stefano Alivernini et al. NATURE MEDICINE
- RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares
- (2020) Dana E. Orange et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes
- (2020) Marc Pfefferlé et al. JOURNAL OF CLINICAL INVESTIGATION
- The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic–epigenetic reprogramming and resolves inflammatory injury
- (2020) Bisheng Zhou et al. NATURE IMMUNOLOGY
- Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis
- (2020) Elisabeth Jäger et al. Nature Communications
- Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
- (2019) Svetoslav Chakarov et al. SCIENCE
- Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
- (2019) Frances Humby et al. ANNALS OF THE RHEUMATIC DISEASES
- The role of macrophages in the resolution of inflammation
- (2019) Satoshi Watanabe et al. JOURNAL OF CLINICAL INVESTIGATION
- Distinct fibroblast subsets drive inflammation and damage in arthritis
- (2019) Adam P. Croft et al. NATURE
- Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
- (2019) Fan Zhang et al. NATURE IMMUNOLOGY
- HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness
- (2019) David Kuo et al. Science Translational Medicine
- Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner
- (2019) Diego Adhemar Jaitin et al. CELL
- Locally renewing resident synovial macrophages provide a protective barrier for the joint
- (2019) Stephan Culemann et al. NATURE
- Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
- (2019) Myles J. Lewis et al. Cell Reports
- Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells
- (2018) S. Alivernini et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy
- (2018) Faye A.H. Cooles et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Association between IL-6 production in synovial explants from rheumatoid arthritis patients and clinical and imaging response to biologic treatment: A pilot study
- (2018) Martin Andersen et al. PLoS One
- Rheumatoid arthritis
- (2018) Josef S. Smolen et al. Nature Reviews Disease Primers
- In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission
- (2018) Emma C de Moel et al. ANNALS OF THE RHEUMATIC DISEASES
- Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen
- (2018) Hwee Ying Lim et al. IMMUNITY
- Methotrexate mechanism in treatment of rheumatoid arthritis
- (2018) Benjamin Friedman et al. JOINT BONE SPINE
- MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
- (2017) Evangelos Triantafyllou et al. GUT
- Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells
- (2017) Allison W. Roberts et al. IMMUNITY
- Immunopathogenesis of Rheumatoid Arthritis
- (2017) Gary S. Firestein et al. IMMUNITY
- Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
- (2017) Alexander V. Misharin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
- (2017) Deepak A. Rao et al. NATURE
- A macrophage relay for long-distance signaling during postembryonic tissue remodeling
- (2017) Dae Seok Eom et al. SCIENCE
- Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells
- (2017) Lidia Bosurgi et al. SCIENCE
- VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism
- (2017) Jialin Li et al. Nature Communications
- CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
- (2017) Xiaomei Yuan et al. eLife
- Sustained remission in rheumatoid arthritis: latest evidence and clinical considerations
- (2017) Sofia Ajeganova et al. Therapeutic Advances in Musculoskeletal Disease
- Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages
- (2016) Lianne van de Laar et al. IMMUNITY
- Tissue-Resident Macrophage Ontogeny and Homeostasis
- (2016) Florent Ginhoux et al. IMMUNITY
- Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization
- (2016) William Lawrance et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Folate Receptor β Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen
- (2016) Christian Machacek et al. JOURNAL OF IMMUNOLOGY
- Tissue biology perspective on macrophages
- (2016) Yasutaka Okabe et al. NATURE IMMUNOLOGY
- MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
- (2016) Bishuang Cai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Relapse rates in patients with rheumatoid arthritis in stable remission tapering or stopping antirheumatic therapy: interim results from the prospective randomised controlled RETRO study
- (2015) Judith Haschka et al. ANNALS OF THE RHEUMATIC DISEASES
- Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment
- (2015) Juergen Rech et al. ANNALS OF THE RHEUMATIC DISEASES
- Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis
- (2015) L Yeo et al. ANNALS OF THE RHEUMATIC DISEASES
- Macrophages: Development and Tissue Specialization
- (2015) Chen Varol et al. Annual Review of Immunology
- Nuclear Receptor Nr4a2 Promotes Alternative Polarization of Macrophages and Confers Protection in Sepsis
- (2015) Sahil Mahajan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IRF5 controls both acute and chronic inflammation
- (2015) Miriam Weiss et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?
- (2015) György Nagy et al. ARTHRITIS RESEARCH & THERAPY
- The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis
- (2015) Ceri A. Roberts et al. Frontiers in Immunology
- Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility
- (2014) Paul Andrew Muller et al. CELL
- Macrophage uptake and accumulation of folates are polarization-dependent in vitro and in vivo and are regulated by activin A
- (2014) Rafael Samaniego et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
- (2014) Christoph Schneider et al. NATURE IMMUNOLOGY
- Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics
- (2014) Glynn Dennis et al. ARTHRITIS RESEARCH & THERAPY
- Synovial explant inflammatory mediator production corresponds to rheumatoid arthritis imaging hallmarks: a cross-sectional study
- (2014) Martin Andersen et al. ARTHRITIS RESEARCH & THERAPY
- Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice
- (2014) Alexander V. Misharin et al. Cell Reports
- Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes
- (2014) Florian Kahles et al. Molecular Metabolism
- New learnings on the pathophysiology of RA from synovial biopsies
- (2013) Costantino Pitzalis et al. CURRENT OPINION IN RHEUMATOLOGY
- Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function
- (2013) Atsushi Nakamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tissue-resident macrophages
- (2013) Luke C Davies et al. NATURE IMMUNOLOGY
- Rapid in situ chondrocyte death induced by Staphylococcus aureus toxins in a bovine cartilage explant model of septic arthritis
- (2013) I.D.M. Smith et al. OSTEOARTHRITIS AND CARTILAGE
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Monocyte migration to the synovium in rheumatoid arthritis patients treated with adalimumab
- (2011) M. M. J. Herenius et al. ANNALS OF THE RHEUMATIC DISEASES
- Unknown
- (2011) Alessandro Michelutti et al. MOLECULAR MEDICINE
- MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
- (2011) M. Kurowska-Stolarska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Changes in hand bone mineral density and the association with the level of disease activity in patients with rheumatoid arthritis: Bone mineral density measurements in a multicenter randomized clinical trial
- (2011) L. Dirven et al. ARTHRITIS CARE & RESEARCH
- Monocyte Scintigraphy in Rheumatoid Arthritis: The Dynamics of Monocyte Migration in Immune-Mediated Inflammatory Disease
- (2009) Rogier M. Thurlings et al. PLoS One
- A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages
- (2008) W. Xia et al. BLOOD
- The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor expression in the synovium
- (2007) C A Wijbrandts et al. ANNALS OF THE RHEUMATIC DISEASES
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