Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves

(2019) Julia Kolter et al.   IMMUNITY

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

(2018) Sebastiaan De Schepper et al.   CELL

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

(2018) Merav Cohen et al.   CELL

Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection

(2017) L Guo et al.   Mucosal Immunology

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages

(2016) Ilana Gabanyi et al.   CELL

Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals

(2016) Catherine M. Sawai et al.   IMMUNITY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis

(2016) Ido Amit et al.   NATURE IMMUNOLOGY

Molecular control of activation and priming in macrophages

(2016) Christopher K Glass et al.   NATURE IMMUNOLOGY

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

IL-17A–producing resident memory γδ T cells orchestrate the innate immune response to secondary oralListeria monocytogenesinfection

(2016) Pablo A. Romagnoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

(2015) Julia Bruttger et al.   IMMUNITY

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

(2015) Camille Blériot et al.   IMMUNITY

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

(2015) L A Borthwick et al.   Mucosal Immunology

Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth

(2015) Sherine Ensan et al.   NATURE IMMUNOLOGY

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping

(2015) Jennifer B Treweek et al.   Nature Protocols

Development and function of tissue resident macrophages in mice

(2015) Katrin Kierdorf et al.   SEMINARS IN IMMUNOLOGY

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility

(2014) Paul Andrew Muller et al.   CELL

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

Transient ablation of alveolar macrophages leads to massive pathology of influenza infection without affecting cellular adaptive immunity

(2014) Christina Purnama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Understanding macrophage diversity at the ontogenic and transcriptomic levels

(2014) Emmanuel L. Gautier et al.   IMMUNOLOGICAL REVIEWS

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Influenza and Endemic Viral Pneumonia

(2013) Clare D. Ramsey et al.   CRITICAL CARE CLINICS

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

(2013) Kari Ann Shirey et al.   NATURE

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress

(2013) Andrew Chow et al.   NATURE MEDICINE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

(2012) Melanie Greter et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Sialoadhesin - a macrophage-restricted marker of immunoregulation and inflammation

(2012) Alexander S. G. O'Neill et al.   IMMUNOLOGY

Innate Immune Functions of Macrophage Subpopulations in the Spleen

(2012) Joke M.M. den Haan et al.   Journal of Innate Immunity

Macrophage-Mediated Inflammation and Disease: A Focus on the Lung

(2012) Emily Gwyer Findlay et al.   MEDIATORS OF INFLAMMATION

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

(2011) D. A. Hume et al.   BLOOD

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

(2011) Oscar Medina-Contreras et al.   JOURNAL OF CLINICAL INVESTIGATION

Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

(2011) Bryna Erblich et al.   PLoS One

CD169+ macrophages at the crossroads of antigen presentation

(2011) Luisa Martinez-Pomares et al.   TRENDS IN IMMUNOLOGY

H1N1: viral pneumonia as a cause of acute respiratory distress syndrome

(2010) Clare Ramsey et al.   Current Opinion in Critical Care

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells

(2010) E. Camilla Forsberg et al.   PLoS One

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE