New learnings on the pathophysiology of RA from synovial biopsies

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

(2012) P L Klarenbeek et al.   ANNALS OF THE RHEUMATIC DISEASES

Evaluation of the contribution of cumulative levels of inflammation to the variance in joint destruction in rheumatoid arthritis

(2012) Rachel Knevel et al.   ANNALS OF THE RHEUMATIC DISEASES

Pretreatment synovial transcriptional profile is associated with early and late clinical response in rheumatoid arthritis patients treated with rituximab

(2012) Vanessa E Hogan et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases

(2012) Elisa Corsiero et al.   IMMUNOLOGY LETTERS

Interferon type I signature may predict non response upon rituximab in rheumatoid arthritis patients

(2012) Hennie G Raterman et al.   ARTHRITIS RESEARCH & THERAPY

Why does chronic inflammation persist: An unexpected role for fibroblasts

(2011) Christopher D. Buckley   IMMUNOLOGY LETTERS

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systematic Review of Medical Treatment in Melanoma: Current Status and Future Prospects

(2011) C. Garbe et al.   ONCOLOGIST

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

(2011) Anak ASSK Dharmapatni et al.   ARTHRITIS RESEARCH & THERAPY

Synovial Tissue Heterogeneity and Peripheral Blood Biomarkers

(2011) Serena Bugatti et al.   Current Rheumatology Reports

Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

(2010) Rogier M. Thurlings et al.   ARTHRITIS AND RHEUMATISM

V-region gene analysis of locally defined synovial B and plasma cells reveals selected B cell expansion and accumulation of plasma cell clones in rheumatoid arthritis

(2010) Tobias Scheel et al.   ARTHRITIS AND RHEUMATISM

Use of standard markers and incorporation of molecular markers into breast cancer therapy

(2010) Manfred Kaufmann et al.   CANCER

B cells in the pathogenesis and treatment of rheumatoid arthritis

(2010) Bethany Marston et al.   CURRENT OPINION IN RHEUMATOLOGY

Pharmacogenomics of infliximab treatment using peripheral blood cells of patients with rheumatoid arthritis

(2010) L G M van Baarsen et al.   GENES AND IMMUNITY

Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers

(2010) Thomas Dörner et al.   PHARMACOLOGY & THERAPEUTICS

The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis

(2010) Johan Lindberg et al.   PLoS One

The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: A prospective study

(2009) Ruth Klaasen et al.   ARTHRITIS AND RHEUMATISM

How to perform and analyse biopsies in relation to connective tissue diseases

(2009) Evelien Ton et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Bone remodeling in rheumatic disease: a question of balance

(2009) Nicole C. Walsh et al.   IMMUNOLOGICAL REVIEWS

Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling

(2009) Antonio Manzo et al.   IMMUNOLOGICAL REVIEWS

Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis

(2009) Valérie Badot et al.   ARTHRITIS RESEARCH & THERAPY

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

(2008) M H Buch et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor   therapy in rheumatoid arthritis

(2008) J D Canete et al.   ANNALS OF THE RHEUMATIC DISEASES

Synovial lymphoid neogenesis does not define a specific clinical rheumatoid arthritis phenotype

(2008) Rogier M. Thurlings et al.   ARTHRITIS AND RHEUMATISM

Liver Myofibroblasts Regulate Infiltration and Positioning of Lymphocytes in Human Liver

(2008) Andrew P. Holt et al.   GASTROENTEROLOGY