A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
Authors
Keywords
-
Journal
Nature Reviews Gastroenterology & Hepatology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-07-21
DOI
10.1038/s41575-022-00649-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Global Disparities in Hepatitis B Elimination—A Focus on Africa
- (2022) Mark W. Sonderup et al. Viruses-Basel
- Capsid Assembly Modulators as Antiviral Agents against HBV: Molecular Mechanisms and Clinical Perspectives
- (2022) Valerio Taverniti et al. Journal of Clinical Medicine
- Characterization and Application of Precore/Core‐Related Antigens in Animal Models of Hepatitis B Virus Infection
- (2021) Xupeng Hong et al. HEPATOLOGY
- Hepatocellular carcinoma
- (2021) Josep M. Llovet et al. Nature Reviews Disease Primers
- Quantitative analysis of the splice variants expressed by the major hepatitis B virus genotypes
- (2021) Chun Shen Lim et al. Microbial Genomics
- Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
- (2021) Nina Le Bert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Analytical validation of hepatitis B core‐related antigen (HBcrAg) using dried blood spots (DBS)
- (2021) Yusuke Shimakawa et al. JOURNAL OF VIRAL HEPATITIS
- Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver
- (2021) Daniel Traum et al. JCI Insight
- Clinical efficacy of a novel, high-sensitivity HBcrAg assay in the management of chronic hepatitis B and HBV reactivation
- (2021) Takako Inoue et al. JOURNAL OF HEPATOLOGY
- Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment
- (2021) Lorenzo Piermatteo et al. METHODS
- The spatial landscape of lung pathology during COVID-19 progression
- (2021) André F. Rendeiro et al. NATURE
- Role of anti-HBs in functional cure of HBeAg+ chronic hepatitis B patients infected with HBV genotype A
- (2021) Hui Xu et al. JOURNAL OF HEPATOLOGY
- The Inflammatory Cytokine Profile Associated With Liver Damage Is Broader and Stronger in Patients With Chronic Hepatitis B Compared to Patients With Acute Hepatitis B
- (2021) Alexandra Johnson Valiente et al. JOURNAL OF INFECTIOUS DISEASES
- Hepatitis B Virus RNA as Early Predictor for Response to Pegylated Interferon Alpha in HBeAg-Negative Chronic Hepatitis B
- (2020) Mina S Farag et al. CLINICAL INFECTIOUS DISEASES
- Epidemiology and surveillance for hepatocellular carcinoma: New trends
- (2020) Amit G. Singal et al. JOURNAL OF HEPATOLOGY
- Full-length 5’RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum
- (2020) Bernd Stadelmayer et al. JOURNAL OF HEPATOLOGY
- Peculiarities in the designations of hepatitis B virus genes, their products, and their antigenic specificities: a potential source of misunderstandings
- (2020) Wolfram H. Gerlich et al. VIRUS GENES
- Challenges for hepatitis B virus cure in resource-limited settings in sub-Saharan Africa
- (2020) Anna Kramvis Current Opinion in HIV and AIDS
- Serum alanine aminotransferase flares in chronic hepatitis B infection: the good and the bad
- (2020) Marc G Ghany et al. Lancet Gastroenterology & Hepatology
- Profiles of serum soluble programmed death-1 and programmed death-ligand 1 levels in chronic hepatitis B virus-infected patients with different disease phases and after anti-viral treatment
- (2020) Juan Xia et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Biomarkers for the Early Detection of Hepatocellular Carcinoma
- (2020) Neehar D Parikh et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
- (2020) Alba Grifoni et al. CELL
- Clinical relevance of the in situ assay for HBV DNA: a cross-sectional study in patients with chronic hepatitis B
- (2020) Danping Liu et al. JOURNAL OF CLINICAL PATHOLOGY
- Ultra-high sensitivity HBsAg assay can diagnose HBV reactivation following rituximab-based therapy in patients with lymphoma
- (2020) Shigeru Kusumoto et al. JOURNAL OF HEPATOLOGY
- Reverse transcriptase droplet digital PCR vs reverse transcriptase quantitative real-time PCR for serum HBV RNA quantification
- (2020) Umaporn Limothai et al. JOURNAL OF MEDICAL VIROLOGY
- The combination of PIVKA‐II and AFP improves the detection accuracy for HCC in HBV caucasian cirrhotics on long‐term oral therapy
- (2020) Alessandro Loglio et al. LIVER INTERNATIONAL
- Pathogenetic Mechanisms of T Cell Dysfunction in Chronic HBV Infection and Related Therapeutic Approaches
- (2020) Paola Fisicaro et al. Frontiers in Immunology
- Editorial: which factors influence HBsAg levels in HBV-infected patients?
- (2020) Markus Cornberg et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Mechanisms of HBV immune evasion
- (2020) Adrian Kuipery et al. ANTIVIRAL RESEARCH
- Circulating Pregenomic HBV RNA is Primarily Full-length in Chronic Hepatitis B Patients Undergoing Nucleos(t)ide Analogue Therapy
- (2020) Mark Anderson et al. CLINICAL INFECTIOUS DISEASES
- Role of serum HBV RNA and hepatitis B surface antigen levels in identifying Asian patients with chronic hepatitis B suitable for entecavir cessation
- (2020) Wai-Kay Seto et al. GUT
- New Blood Biomarkers for the Diagnosis of AFP-Negative Hepatocellular Carcinoma
- (2020) Ting Wang et al. Frontiers in Oncology
- Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
- (2020) Daniela Weiskopf et al. Science Immunology
- Liquid biopsy in the clinical management of hepatocellular carcinoma
- (2020) Johann von Felden et al. GUT
- Efficacy and safety of GLS4/ritonavir combined with entecavir in HBeAg-positive patients with chronic hepatitis B: interim results from phase 2b, multi-center study
- (2020) Mingyuan Zhang et al. JOURNAL OF HEPATOLOGY
- Composition of HBsAg is predictive of HBsAg loss during treatment in patients with HBeAg-positive chronic hepatitis B
- (2020) Maria Pfefferkorn et al. JOURNAL OF HEPATOLOGY
- Real‐world application of the Xpert® HBV viral load assay on serum and dried blood spots
- (2020) Kathy Jackson et al. JOURNAL OF MEDICAL VIROLOGY
- HBV RNA Profiles in Patients With Chronic Hepatitis B Under Different Disease Phases and Antiviral Therapy
- (2020) Lung‐Yi Mak et al. HEPATOLOGY
- Impact of hepatitis B core-related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues
- (2019) Tetsuya Hosaka et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection
- (2019) Man Fung Yuen et al. GASTROENTEROLOGY
- Update of the statements on biology and clinical impact of occult hepatitis b virus infection
- (2019) Giovanni Raimondo et al. JOURNAL OF HEPATOLOGY
- Elevated serum levels of soluble CD14 in HBeAg‐positive chronic HBV patients upon Peginterferon treatment are associated with treatment response
- (2019) Yingying Dou et al. JOURNAL OF VIRAL HEPATITIS
- Discrepant range of sPD ‐1 in different studies of Chronic hepatitis B
- (2019) Wen‐Juei Jeng et al. JOURNAL OF VIRAL HEPATITIS
- Hepatitis B core‐related antigen monitoring during peginterferon alfa treatment for HB eAg‐negative chronic hepatitis B
- (2019) Margo J.H. van Campenhout et al. JOURNAL OF VIRAL HEPATITIS
- Global Elimination of Chronic Hepatitis
- (2019) David L. Thomas NEW ENGLAND JOURNAL OF MEDICINE
- Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B
- (2019) Kyong-Mi Chang et al. PLoS Pathogens
- Meeting the Challenge of Eliminating Chronic Hepatitis B Infection
- (2019) Peter A. Revill et al. Genes
- Letter: impact of hepatitis B core-related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues-further clarifications needed. Authors’ reply
- (2019) Tetsuya Hosaka ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Association Between Negative Results From Tests for HBV DNA and RNA and Durability of Response After Discontinuation of Nucles(t)ide Analogue Therapy
- (2019) Rong Fan et al. Clinical Gastroenterology and Hepatology
- A global scientific strategy to cure hepatitis B
- (2019) Peter A Revill et al. Lancet Gastroenterology & Hepatology
- High Level of Hepatitis B Core-related Antigen Associated With Increased Risk of Hepatocellular Carcinoma in Patients With Chronic HBV Infection of Intermediate Viral Load
- (2019) Tai-Chung Tseng et al. GASTROENTEROLOGY
- Improved detection of early acute, late acute, and occult Hepatitis B infections by an increased sensitivity HBsAg assay
- (2019) Mary C. Kuhns et al. JOURNAL OF CLINICAL VIROLOGY
- Therapeutic strategies for hepatitis B virus infection: towards a cure
- (2019) Gregory C. Fanning et al. NATURE REVIEWS DRUG DISCOVERY
- Restoring, releasing or replacing adaptive immunity in chronic hepatitis B
- (2019) Mala K. Maini et al. Nature Reviews Gastroenterology & Hepatology
- Performance of the Xpert HBV Viral Load assay versus the Aptima Quant assay for quantifying hepatitis B virus DNA
- (2019) Florence Abravanel et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Pre‐genomic HBV RNA and HBcrAg predict outcomes in HBeAg negative chronic hepatitis B patients suppressed on nucleos(t)ide analogue therapy
- (2019) Ivana Carey et al. HEPATOLOGY
- Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference
- (2019) Markus Cornberg et al. JOURNAL OF HEPATOLOGY
- Immune monitoring using mass cytometry and related high-dimensional imaging approaches
- (2019) Felix J. Hartmann et al. Nature Reviews Rheumatology
- Letter: serum HBcrAg is a useful marker for disease monitoring, predicting treatment response and disease outcome of chronic hepatitis B virus infection-authors' reply
- (2018) L.-Y. Mak et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Predictive role of serum HBsAg and HBcrAg kinetics in patients with HBeAg-negative chronic hepatitis B receiving pegylated interferon–based therapy
- (2018) N. Chuaypen et al. CLINICAL MICROBIOLOGY AND INFECTION
- Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection
- (2018) Klaus Klumpp et al. GASTROENTEROLOGY
- Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis
- (2018) Kristina Tzartzeva et al. GASTROENTEROLOGY
- Multiple HBV transfusion transmissions from undetected occult infections: revising the minimal infectious dose
- (2018) Daniel Candotti et al. GUT
- Host and viral factors associated with serum hepatitis B virus RNA levels among patients in need for treatment
- (2018) Margo J.H. van Campenhout et al. HEPATOLOGY
- HBV serum DNA and RNA levels in nucleos(t)ide analogue-treated or untreated patients during chronic and acute infection
- (2018) Emily K. Butler et al. HEPATOLOGY
- Hepatitis B virus core-related antigen levels predict progression to liver cirrhosis in hepatitis B carriers
- (2018) Toshifumi Tada et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Relationship between serum HBV-RNA levels and intrahepatic viral as well as histologic activity markers in entecavir-treated patients
- (2018) Jing Wang et al. JOURNAL OF HEPATOLOGY
- HBV RNA virion-like particles produced under nucleos(t)ide analogues treatment are mainly replication-deficient
- (2018) Jie Wang et al. JOURNAL OF HEPATOLOGY
- New virological tools for screening, diagnosis and monitoring of hepatitis B and C in resource-limited settings
- (2018) Stéphane Chevaliez et al. JOURNAL OF HEPATOLOGY
- Quantitation of HBV cccDNA in anti-HBc-positive liver donors by droplet digital PCR: A new tool to detect occult infection
- (2018) Gian Paolo Caviglia et al. JOURNAL OF HEPATOLOGY
- Quantification of HBV core antibodies may help predict HBV reactivation in patients with lymphoma and resolved HBV infection
- (2018) Hung-Chih Yang et al. JOURNAL OF HEPATOLOGY
- Serum HBV RNA as a Predictor of Peginterferon Alfa-2a Response in Patients With HBeAg-Positive Chronic Hepatitis B
- (2018) Florian van Bömmel et al. JOURNAL OF INFECTIOUS DISEASES
- Natural history of serum HBV-RNA in chronic HBV infection
- (2018) J. Wang et al. JOURNAL OF VIRAL HEPATITIS
- ALT flares during nucleotide analogue therapy are associated with HBsAg loss in genotype A HBeAg-positive chronic hepatitis B
- (2018) Darren Wong et al. LIVER INTERNATIONAL
- High serum levels of pregenomic RNA reflect frequently failing reverse transcription in hepatitis B virus particles
- (2018) Kasthuri Prakash et al. Virology Journal
- Hepatitis B virus infection
- (2018) Man-Fung Yuen et al. Nature Reviews Disease Primers
- Longitudinal Assessment of Three Serum Biomarkers to Detect Very Early Stage Hepatocellular Carcinoma
- (2018) Jonggi Choi et al. HEPATOLOGY
- PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection
- (2018) Loghman Salimzadeh et al. JOURNAL OF CLINICAL INVESTIGATION
- Performance of Serum Glypican 3 in Diagnosis of Hepatocellular Carcinoma: A meta-analysis
- (2018) Dahai Xu et al. Annals of Hepatology
- New and Old Biomarkers for Diagnosis and Management of Chronic Hepatitis B Virus Infection
- (2018) Carla S. Coffin et al. GASTROENTEROLOGY
- Insights From Antiviral Therapy Into Immune Responses to Hepatitis B and C Virus Infection
- (2018) Barbara Rehermann et al. GASTROENTEROLOGY
- Fine needle aspirates comprehensively sample intrahepatic immunity
- (2018) Upkar S Gill et al. GUT
- Hepatitis B virus (HBV)-infected patients with low hepatitis B surface antigen and high hepatitis B core-related antigen titers have a high risk of HBV-related hepatocellular carcinoma
- (2018) Yuichiro Suzuki et al. HEPATOLOGY RESEARCH
- Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients
- (2018) Barbara Testoni et al. JOURNAL OF HEPATOLOGY
- Soluble programmed death-1 is a useful indicator for inflammatory and fibrosis severity in chronic hepatitis B
- (2018) Liang Zhou et al. JOURNAL OF VIRAL HEPATITIS
- Serum Hepatitis B core-related antigen is an effective tool to categorize patients with HBeAg-negative Chronic Hepatitis B
- (2018) Elisabetta Loggi et al. JOURNAL OF VIRAL HEPATITIS
- Extracellular Hepatitis B Virus RNAs Are Heterogeneous in Length and Circulate as Capsid-Antibody Complexes in Addition to Virions in Chronic Hepatitis B Patients
- (2018) Lu Bai et al. JOURNAL OF VIROLOGY
- Quantification of large and middle proteins of hepatitis B virus surface antigen (HBsAg) as a novel tool for the identification of inactive HBV carriers
- (2017) Maria Pfefferkorn et al. GUT
- Analysis of hepatitis B surface antigen (HBsAg) using high-sensitivity HBsAg assays in hepatitis B virus carriers in whom HBsAg seroclearance was confirmed by conventional assays
- (2017) Itaru Ozeki et al. HEPATOLOGY RESEARCH
- Evaluation of the highly sensitive chemiluminescent enzyme immunoassay “Lumipulse HBsAg-HQ” for hepatitis B virus screening
- (2017) Matsuo Deguchi et al. JOURNAL OF CLINICAL LABORATORY ANALYSIS
- Performance of HBsAg quantification assays for detection of Hepatitis B virus genotypes and diagnostic escape-variants in clinical samples
- (2017) Vincent Thibault et al. JOURNAL OF CLINICAL VIROLOGY
- Evaluation of serum HBV RNA and HBcrAg in chronic hepatitis B patients achieving different serological outcomes on tenofovir disoproxil fumarate (TDF)
- (2017) A.L. Cathcart et al. JOURNAL OF HEPATOLOGY
- Reply to: “Serum HBV pgRNA as a clinical marker for cccDNA activity”
- (2017) Jie Wang et al. JOURNAL OF HEPATOLOGY
- Serum HBV pgRNA as a clinical marker for cccDNA activity
- (2017) Katja Giersch et al. JOURNAL OF HEPATOLOGY
- Hepatitis B cure: From discovery to regulatory approval
- (2017) Anna S. Lok et al. JOURNAL OF HEPATOLOGY
- The role of quantitative hepatitis B surface antigen revisited
- (2017) Markus Cornberg et al. JOURNAL OF HEPATOLOGY
- EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
- (2017) Pietro Lampertico et al. JOURNAL OF HEPATOLOGY
- Mucosal-Associated Invariant T Cells Are More Activated in Chronic Hepatitis B, but Not Depleted in Blood: Reversal by Antiviral Therapy
- (2017) Lauke L Boeijen et al. JOURNAL OF INFECTIOUS DISEASES
- Development of a digital droplet PCR assay to measure HBV DNA in patients receiving long-term TDF treatment
- (2017) Yang Liu et al. JOURNAL OF VIROLOGICAL METHODS
- Hepatitis B virus long-term impact of antiviral therapy nucleot(s)ide analogues (NUCs)
- (2017) Glenda Grossi et al. LIVER INTERNATIONAL
- Hepatitis B virus core-related antigen as a surrogate marker for covalently closed circular DNA
- (2017) Danny Ka-Ho Wong et al. LIVER INTERNATIONAL
- Usefulness of AFP, AFP-L3, and PIVKA-II, and their combinations in diagnosing hepatocellular carcinoma
- (2017) Sang Joon Park et al. MEDICINE
- Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B
- (2017) Paola Fisicaro et al. NATURE MEDICINE
- RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg
- (2017) Christine I. Wooddell et al. Science Translational Medicine
- Challenges to a Cure for HBV Infection
- (2017) Barbara Testoni et al. SEMINARS IN LIVER DISEASE
- Comparative characterization of hepatitis B virus surface antigen derived from different hepatitis B virus genotypes
- (2017) Matthias Hassemer et al. VIROLOGY
- Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts
- (2017) et al. Viruses-Basel
- Complete and Incomplete Hepatitis B Virus Particles: Formation, Function, and Application
- (2017) Jianming Hu et al. Viruses-Basel
- The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
- (2017) Congrong Niu et al. PLoS One
- Serum hepatitis B core-related antigen is a satisfactory surrogate marker of intrahepatic covalently closed circular DNA in chronic hepatitis B
- (2017) En-Qiang Chen et al. Scientific Reports
- Predictors of adequate ultrasound quality for hepatocellular carcinoma surveillance in patients with cirrhosis
- (2016) O. Simmons et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Virus and Host Testing to Manage Chronic Hepatitis B
- (2016) Grace Lai-Hung Wong et al. CLINICAL INFECTIOUS DISEASES
- Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen–positive chronic hepatitis B patients
- (2016) M.J.H. van Campenhout et al. CLINICAL MICROBIOLOGY AND INFECTION
- Evolution in Our Understanding of Hepatitis B Virus Virology and Immunology
- (2016) Bertram Bengsch et al. Clinics in Liver Disease
- Deep sequencing shows that HBV basal core promoter and precore variants reduce the likelihood of HBsAg loss following tenofovir disoproxil fumarate therapy in HBeAg-positive chronic hepatitis B
- (2016) Julianne Bayliss et al. GUT
- In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection
- (2016) Xiaonan Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of innate immunity in the immunopathology and treatment of HBV infection
- (2016) Mala K. Maini et al. JOURNAL OF HEPATOLOGY
- Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound
- (2016) Jie Wang et al. JOURNAL OF HEPATOLOGY
- Overview of hepatitis B viral replication and genetic variability
- (2016) Shuping Tong et al. JOURNAL OF HEPATOLOGY
- Adaptive immunity in HBV infection
- (2016) Antonio Bertoletti et al. JOURNAL OF HEPATOLOGY
- Prediction models of hepatocellular carcinoma development in chronic hepatitis B patients
- (2016) Hye Won Lee et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities
- (2015) Robert G. Gish et al. ANTIVIRAL RESEARCH
- Chronic hepatitis B: role of anti-platelet therapy in inflammation control
- (2015) Roberto Aiolfi et al. Cellular & Molecular Immunology
- Update on Biomarkers of Hepatocellular Carcinoma
- (2015) Roongruedee Chaiteerakij et al. Clinical Gastroenterology and Hepatology
- Hepatitis B core-related antigen (HBcrAg) levels in the natural history of hepatitis B virus infection in a large European cohort predominantly infected with genotypes A and D
- (2015) B. Maasoumy et al. CLINICAL MICROBIOLOGY AND INFECTION
- Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B
- (2015) Sachiyo Yoshio et al. HEPATOLOGY
- Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues
- (2015) L. Jansen et al. JOURNAL OF INFECTIOUS DISEASES
- Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma
- (2015) Masao Honda et al. JOURNAL OF INFECTIOUS DISEASES
- Diagnostic values of alpha-fetoprotein, dickkopf-1, and osteopontin for hepatocellular carcinoma
- (2015) Tianxiang Ge et al. MEDICAL ONCOLOGY
- Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells
- (2015) Laura J Pallett et al. NATURE MEDICINE
- ELISA in the multiplex era: Potentials and pitfalls
- (2015) Patrick J. Tighe et al. Proteomics Clinical Applications
- Predictive value of interferon-gamma inducible protein 10kD for hepatitis B e antigen clearance and hepatitis B surface antigen decline during pegylated interferon alpha therapy in chronic hepatitis B patients
- (2014) Yadong Wang et al. ANTIVIRAL RESEARCH
- On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogue therapy
- (2014) Yi-Wen Huang et al. ANTIVIRAL THERAPY
- Factors That Affect Efficacy of Ultrasound Surveillance for Early Stage Hepatocellular Carcinoma in Patients With Cirrhosis
- (2014) Paolo Del Poggio et al. Clinical Gastroenterology and Hepatology
- Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B
- (2014) W.-K. Seto et al. CLINICAL MICROBIOLOGY AND INFECTION
- Serum hepatitis B virus RNA levels as an early predictor of hepatitis B envelope antigen seroconversion during treatment with polymerase inhibitors
- (2014) Florian van Bömmel et al. HEPATOLOGY
- Genotypes and Genetic Variability of Hepatitis B Virus
- (2014) Anna Kramvis INTERVIROLOGY
- Hepatitis B Reactivation in Patients With Previous Hepatitis B Virus Exposure Undergoing Rituximab-Containing Chemotherapy for Lymphoma: A Prospective Study
- (2014) Wai-Kay Seto et al. JOURNAL OF CLINICAL ONCOLOGY
- Circulating Programmed Death-1 as a Marker for Sustained High Hepatitis B Viral Load and Risk of Hepatocellular Carcinoma
- (2014) Hsiang-Yun Cheng et al. PLoS One
- Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA
- (2014) J. Lucifora et al. SCIENCE
- The Detection of Hepatocellular Carcinoma Using a Prospectively Developed and Validated Model Based on Serological Biomarkers
- (2013) P. J. Johnson et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Factors That Affect Accuracy of α-Fetoprotein Test in Detection of Hepatocellular Carcinoma in Patients With Cirrhosis
- (2013) Purva Gopal et al. Clinical Gastroenterology and Hepatology
- Risk of occult hepatitis B virus infection reactivation in patients with solid tumours undergoing chemotherapy
- (2013) Carlo Saitta et al. DIGESTIVE AND LIVER DISEASE
- On-treatment alpha-fetoprotein is a specific tumor marker for hepatocellular carcinoma in patients with chronic hepatitis B receiving entecavir
- (2013) Grace L.H. Wong et al. HEPATOLOGY
- Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients
- (2013) Masataka Tsuge et al. JOURNAL OF GASTROENTEROLOGY
- Significance of hepatitis B virus core-related antigen and covalently closed circular DNA levels as markers of hepatitis B virus re-infection after liver transplantation
- (2013) Toshihisa Matsuzaki et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B
- (2013) Milan J. Sonneveld et al. JOURNAL OF HEPATOLOGY
- Rapid downregulation of programmed death-1 and interferon-γ-inducible protein-10 expression is associated with favourable outcome during antiviral treatment of chronic hepatitis B
- (2013) F.-Q. Hou et al. JOURNAL OF VIRAL HEPATITIS
- Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?
- (2013) Mohamad S. Hakim et al. REVIEWS IN MEDICAL VIROLOGY
- Improving Screening for Hepatocellular Carcinoma by Incorporating Data on Levels of α-Fetoprotein, Over Time
- (2012) Elliot Lee et al. Clinical Gastroenterology and Hepatology
- Increased Levels of Arginase in Patients With Acute Hepatitis B Suppress Antiviral T Cells
- (2012) Elena Sandalova et al. GASTROENTEROLOGY
- HBsAg variants: Diagnostic-escape and diagnostic dilemma
- (2012) Seyed Moayed Alavian et al. JOURNAL OF CLINICAL VIROLOGY
- Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion
- (2012) Dimitra Peppa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hepatitis B surface antigen (HBsAg) decrease and serum interferon-inducible protein-10 levels as predictive markers for HBsAg loss during treatment with nucleoside/nucleotide analogues
- (2011) Jerzy Jaroszewicz et al. ANTIVIRAL THERAPY
- Development of a sandwich ELISA for evaluating soluble PD-L1 (CD274) in human sera of different ages as well as supernatants of PD-L1+ cell lines
- (2011) Yongjing Chen et al. CYTOKINE
- Prospective Evaluation of FibroScan for the Diagnosis of Hepatic Fibrosis Compared with Liver Biopsy/AST Platelet Ratio Index and FIB-4 in Patients with Chronic HBV Infection
- (2011) Xia Zhu et al. DIGESTIVE DISEASES AND SCIENCES
- Host Response to Translocated Microbial Products Predicts Outcomes of Patients With HBV or HCV Infection
- (2011) Netanya G. Sandler et al. GASTROENTEROLOGY
- Hepatitis B virus transmission by blood transfusion during 4 years of individual-donation nucleic acid testing in South Africa: estimated and observed window period risk
- (2011) Marion Vermeulen et al. TRANSFUSION
- Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus
- (2011) Xiaojun Ning et al. PLoS Pathogens
- Sensitive Assay for Quantification of Hepatitis B Virus Mutants by Use of a Minor Groove Binder Probe and Peptide Nucleic Acids
- (2010) Shuhei Hige et al. JOURNAL OF CLINICAL MICROBIOLOGY
- A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B
- (2010) Anthony T. Tan et al. JOURNAL OF HEPATOLOGY
- Refinement of a viral transmission risk model for blood donations in seroconversion window phase screened by nucleic acid testing in different pool sizes and repeat test algorithms
- (2010) Jos Weusten et al. TRANSFUSION
- Immune tolerance: What is unique about the liver
- (2009) Gisa Tiegs et al. JOURNAL OF AUTOIMMUNITY
- Close monitoring of serum HBV DNA levels and liver enzymes levels is most useful in the management of patients with occult HBV infection
- (2009) Isabelle Chemin et al. JOURNAL OF HEPATOLOGY
- Characterization of Genotype-Specific Carboxyl-Terminal Cleavage Sites of Hepatitis B Virus e Antigen Precursor and Identification of Furin as the Candidate Enzyme
- (2009) K. Ito et al. JOURNAL OF VIROLOGY
- Performance evaluation of 70 hepatitis B virus (HBV) surface antigen (HBsAg) assays from around the world by a geographically diverse panel with an array of HBV genotypes and HBsAg subtypes
- (2009) H. Scheiblauer et al. VOX SANGUINIS
- Posttranscriptional control of HBV gene expression
- (2008) Gunhild Sommer Frontiers in Bioscience-Landmark
- Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection
- (2008) A. Ross Lopes et al. JOURNAL OF CLINICAL INVESTIGATION
- Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
- (2008) Abhishek Das et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Statements from the Taormina expert meeting on occult hepatitis B virus infection
- (2008) Giovanni Raimondo et al. JOURNAL OF HEPATOLOGY
- Correlation between serum hepatitis B virus core-related antigen and intrahepatic covalently closed circular DNA in chronic hepatitis B patients
- (2008) Fumitaka Suzuki et al. JOURNAL OF MEDICAL VIROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started