Systematic discovery of biomolecular condensate-specific protein phosphorylation

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

(2021) Carolina Alquezar et al.   Frontiers in Neurology

High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

(2021) Brian D. Freibaum et al.   JOURNAL OF CELL BIOLOGY

How multisite phosphorylation impacts the conformations of intrinsically disordered proteins

(2021) Fan Jin et al.   PLoS Computational Biology

O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics

(2021) Michael L. Nosella et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Impact of phosphorylation on thermal stability of proteins

(2021) Clément M. Potel et al.   NATURE METHODS

Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization

(2021) Sean R. Kundinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell cycle profiling reveals protein oscillation, phosphorylation, and localization dynamics.

(2020) Patrick Herr et al.   MOLECULAR & CELLULAR PROTEOMICS

Composition-dependent thermodynamics of intracellular phase separation

(2020) Joshua A. Riback et al.   NATURE

Biomolecular condensates as arbiters of biochemical reactions inside the nucleus

(2020) Guillaume Laflamme et al.   Communications Biology

Illuminating the dark phosphoproteome

(2019) Elise J. Needham et al.   Science Signaling

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

(2019) Brian Tsang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PhaSepDB: a database of liquid–liquid phase separation related proteins

(2019) Kaiqiang You et al.   NUCLEIC ACIDS RESEARCH

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

FAM98A is localized to stress granules and associates with multiple stress granule-localized proteins

(2018) Kanako Ozeki et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Kinase-controlled phase transition of membraneless organelles in mitosis

(2018) Arpan Kumar Rai et al.   NATURE

Phosphopeptide Fragmentation and Site Localization by Mass Spectrometry: An Update

(2018) Clement M. Potel et al.   ANALYTICAL CHEMISTRY

Friend or foe — post-translational modifications as regulators of phase separation and RNP granule dynamics

(2018) Mario Hofweber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

RNA gets in phase

(2017) Shambaditya Saha et al.   JOURNAL OF CELL BIOLOGY

A deep learning and novelty detection framework for rapid phenotyping in high-content screening

(2017) Christoph Sommer et al.   MOLECULAR BIOLOGY OF THE CELL

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications

(2016) Alaji Bah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1

(2016) Lucas C. Reineke et al.   MOLECULAR AND CELLULAR BIOLOGY

An atlas of human kinase regulation

(2016) David Ochoa et al.   Molecular Systems Biology

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

The BioPlex Network: A Systematic Exploration of the Human Interactome

(2015) Edward L. Huttlin et al.   CELL

Relating sequence encoded information to form and function of intrinsically disordered proteins

(2015) Rahul K Das et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Cadmium–cysteine coordination in the BK inner pore region and its structural and functional implications

(2015) Yu Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion Coalescence of Neutron Encoded TMT 10-Plex Reporter Ions

(2014) Thilo Werner et al.   ANALYTICAL CHEMISTRY

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards

(2014) Jacek R. Wiśniewski et al.   MOLECULAR & CELLULAR PROTEOMICS

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

(2014) Alaji Bah et al.   NATURE

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling

(2014) Rajat Roy et al.   NUCLEIC ACIDS RESEARCH

hCLE/C14orf166 Associates with DDX1-HSPC117-FAM98B in a Novel Transcription-Dependent Shuttling RNA-Transporting Complex

(2014) Alicia Pérez-González et al.   PLoS One

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

D2P2: database of disordered protein predictions

(2012) Matt E. Oates et al.   NUCLEIC ACIDS RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Assembly and disassembly of the nucleolus during the cell cycle

(2011) Danièle Hernandez-Verdun   Nucleus

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation

(2010) Marc Schneider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines

(2009) S. M. Hearst et al.   JOURNAL OF CELL SCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

(2008) Ina Poser et al.   NATURE METHODS