A deep learning and novelty detection framework for rapid phenotyping in high-content screening

Automated analysis of high‐content microscopy data with deep learning

(2017) Oren Z Kraus et al.   Molecular Systems Biology

Classifying and segmenting microscopy images with deep multiple instance learning

(2016) Oren Z. Kraus et al.   BIOINFORMATICS

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

(2016) Sara Cuylen et al.   NATURE

High-Content Screening for Quantitative Cell Biology

(2016) Mojca Mattiazzi Usaj et al.   TRENDS IN CELL BIOLOGY

Microscopy-Based High-Content Screening

(2015) Michael Boutros et al.   CELL

Deep learning

(2015) Yann LeCun et al.   NATURE

A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking

(2014) Prisca Liberali et al.   CELL

A review of novelty detection

(2014) Marco A.F. Pimentel et al.   SIGNAL PROCESSING

CellH5: a format for data exchange in high-content screening

(2013) Christoph Sommer et al.   BIOINFORMATICS

Unsupervised automated high throughput phenotyping of RNAi time-lapse movies

(2013) Henrik Failmezger et al.   BMC BIOINFORMATICS

Machine learning in cell biology – teaching computers to recognize phenotypes

(2013) Christoph Sommer et al.   JOURNAL OF CELL SCIENCE

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

(2013) Zheng Yin et al.   NATURE CELL BIOLOGY

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

(2012) Thorkell Gudjonsson et al.   CELL

Unsupervised modeling of cell morphology dynamics for time-lapse microscopy

(2012) Qing Zhong et al.   NATURE METHODS

PhenoRipper: software for rapidly profiling microscopy images

(2012) Satwik Rajaram et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Enhanced CellClassifier: a multi-class classification tool for microscopy images

(2010) Benjamin Misselwitz et al.   BMC BIOINFORMATICS

Automated microscopy for high-content RNAi screening

(2010) Christian Conrad et al.   JOURNAL OF CELL BIOLOGY

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

(2010) Michael H. A. Schmitz et al.   NATURE CELL BIOLOGY

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging

(2010) Michael Held et al.   NATURE METHODS

CellClassifier: supervised learning of cellular phenotypes

(2009) Pauli Rämö et al.   BIOINFORMATICS

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

(2009) Thouis R. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens

(2008) Zheng Yin et al.   BMC BIOINFORMATICS