Role of astrocyte-synapse interactions in CNS disorders

Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice

(2016) R. Jiang et al.   JOURNAL OF NEUROSCIENCE

The degeneration of dopaminergic synapses in Parkinson's disease: A selective animal model

(2015) Ingrid Morales et al.   BEHAVIOURAL BRAIN RESEARCH

Astrocytic TNFα regulates the behavioral response to antidepressants

(2015) Rachna Duseja et al.   BRAIN BEHAVIOR AND IMMUNITY

Taming Glutamate Excitotoxicity: Strategic Pathway Modulation for Neuroprotection

(2015) Ming Jia et al.   CNS DRUGS

Enhanced astroglial Ca2+signaling increases excitatory synaptic strength in the epileptic brain

(2015) Carla Álvarez-Ferradas et al.   GLIA

Impaired CO2sensitivity of astrocytes in a mouse model of Rett syndrome

(2015) Egor Turovsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dysregulation of astrocyte extracellular signaling in Costello syndrome

(2015) Robert Krencik et al.   Science Translational Medicine

Astrocyte Regulation of Synaptic Behavior

(2014) Nicola J. Allen   Annual Review of Cell and Developmental Biology

Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability

(2014) Yann Bernardinelli et al.   CURRENT BIOLOGY

Disruption of dopaminergic transmission remodels tripartite synapse morphology and astrocytic calcium activity within substantia nigra pars reticulata

(2014) Anthony Bosson et al.   GLIA

Chromosome fragility and the abnormal replication of the FMR1 locus in fragile X syndrome

(2014) Dmitry Yudkin et al.   HUMAN MOLECULAR GENETICS

Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons

(2014) Emily Cunningham Williams et al.   HUMAN MOLECULAR GENETICS

Distinct Subunit-specific α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Trafficking Mechanisms in Cultured Cortical and Hippocampal Neurons in Response to Oxygen and Glucose Deprivation

(2014) Elena Blanco-Suarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Plasticity of Astrocyte Processes and Dendritic Spine Interactions

(2014) A. Perez-Alvarez et al.   JOURNAL OF NEUROSCIENCE

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

Huntington disease: natural history, biomarkers and prospects for therapeutics

(2014) Christopher A. Ross et al.   Nature Reviews Neurology

Novel astrocyte targets

(2014) Vincenzo Crunelli et al.   NEUROSCIENTIST

Astrocytic Dysfunction and Addiction

(2014) Michael D. Scofield et al.   NEUROSCIENTIST

Care of the Adult Patient with Down Syndrome

(2014) Whitney Trotter Ross et al.   SOUTHERN MEDICAL JOURNAL

Dendritic spine dysgenesis in Rett syndrome

(2014) Xin Xu et al.   Frontiers in Neuroanatomy

The RASopathies

(2013) Katherine A. Rauen   Annual Review of Genomics and Human Genetics

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse

(2013) Haruki Higashimori et al.   HUMAN MOLECULAR GENETICS

Actin filaments and microtubules in dendritic spines

(2013) Tomoaki Shirao et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid-β Inhibits Thrombospondin 1 Release From Cultured Astrocytes: Effects on Synaptic Protein Expression

(2013) Kakulavarapu V. Rama Rao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease

(2013) R. P. Murmu et al.   JOURNAL OF NEUROSCIENCE

Systemic Delivery of MeCP2 Rescues Behavioral and Cellular Deficits in Female Mouse Models of Rett Syndrome

(2013) S. K. Garg et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

Astrocytic therapies for neuronal repair in stroke

(2013) Amy J. Gleichman et al.   NEUROSCIENCE LETTERS

Mechanism-Based Treatments in Neurodevelopmental Disorders: Fragile X Syndrome

(2013) Elizabeth Berry-Kravis   PEDIATRIC NEUROLOGY

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies

(2013) Robert Krencik et al.   Frontiers in Cellular Neuroscience

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Clozapine, but not haloperidol, enhances glial d-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes

(2012) Shunske Tanahashi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Down Syndrome and Thyroid Function

(2012) Evan Graber et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Stem cells and modeling of autism spectrum disorders

(2012) Beatriz C.G. Freitas et al.   EXPERIMENTAL NEUROLOGY

Astrocyte calcium signaling and epilepsy

(2012) Giorgio Carmignoto et al.   GLIA

Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion

(2012) T M Ma et al.   MOLECULAR PSYCHIATRY

Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma

(2012) Huifang Li et al.   NEUROBIOLOGY OF DISEASE

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning

(2012) Sreedeep Mukherjee et al.   NEUROPHARMACOLOGY

Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

(2012) Yasunori Okabe et al.   PLoS One

Synapses and Alzheimer's Disease

(2012) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Experimental models of Rett syndrome based on Mecp2 dysfunction

(2011) Gaston Calfa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Astrocytes Control Glutamate Receptor Levels at Developing Synapses through SPARC- -Integrin Interactions

(2011) E. V. Jones et al.   JOURNAL OF NEUROSCIENCE

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

A role for glia in the progression of Rett’s syndrome

(2011) Daniel T. Lioy et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC

(2011) Hakan Kucukdereli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rett syndrome: Revised diagnostic criteria and nomenclature

(2010) Jeffrey L. Neul et al.   ANNALS OF NEUROLOGY

Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression

(2010) Shelley Jacobs et al.   BMC NEUROSCIENCE

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Implication of Kir4.1 Channel in Excess Potassium Clearance: An In Vivo Study on Anesthetized Glial-Conditional Kir4.1 Knock-Out Mice

(2010) O. Chever et al.   JOURNAL OF NEUROSCIENCE

Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse

(2010) S. Jacobs et al.   JOURNAL OF NEUROSCIENCE

A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome

(2010) Octavio Garcia et al.   PLoS One

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

(2009) William E Tidyman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dendritic spine formation and stabilization

(2009) Yoshihiro Yoshihara et al.   CURRENT OPINION IN NEUROBIOLOGY

Understanding the Role of DISC1 in Psychiatric Disease and during Normal Development

(2009) N. J. Brandon et al.   JOURNAL OF NEUROSCIENCE

Aberrant expression of synaptic plasticity-related genes in the NF1+/−mouse hippocampus

(2009) Chang Sin Park et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

(2009) Nurit Ballas et al.   NATURE NEUROSCIENCE

The glutamate homeostasis hypothesis of addiction

(2009) Peter W. Kalivas   NATURE REVIEWS NEUROSCIENCE

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke

(2008) Jason Liauw et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Two-Photon Imaging during Prolonged Middle Cerebral Artery Occlusion in Mice Reveals Recovery of Dendritic Structure after Reperfusion

(2008) P. Li et al.   JOURNAL OF NEUROSCIENCE

Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades

(2008) M. Matos et al.   NEUROSCIENCE

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

(2008) M. Kvajo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA