Evolution of genetic mechanisms regulating cortical neurogenesis

Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes

(2022) Peter Kozulin et al.   DEVELOPMENT

miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation

(2022) Ugo Tomasello et al.   Cell Reports

Evolution of the Neocortex Through RNA-Binding Proteins and Post-transcriptional Regulation

(2022) Iva Salamon et al.   Frontiers in Neuroscience

Secondary loss of miR-3607 reduced cortical progenitor amplification during rodent evolution

(2022) Kaviya Chinnappa et al.   Science Advances

The evolution of brain neuron numbers in amniotes

(2022) Kristina Kverková et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D Genome of macaque fetal brain reveals evolutionary innovations during primate corticogenesis

(2021) Xin Luo et al.   CELL

From stem and progenitor cells to neurons in the developing neocortex – key differences among hominids

(2021) Felipe Mora‐Bermúdez et al.   FEBS Journal

Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment

(2021) Cleber A. Trujillo et al.   SCIENCE

MiRNAs in early brain development and pediatric cancer

(2021) Anna Prieto‐Colomina et al.   BIOESSAYS

An early cell shape transition drives evolutionary expansion of the human forebrain

(2021) Silvia Benito-Kwiecinski et al.   CELL

Expression of human‐specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility

(2021) Lei Xing et al.   EMBO JOURNAL

The RNA-Binding Protein HuD Regulates Alternative Splicing and Alternative Polyadenylation in the Mouse Neocortex

(2021) Rebecca M. Sena et al.   MOLECULES

Human-Specific Genes, Cortical Progenitor Cells, and Microcephaly

(2021) Michael Heide et al.   Cells

Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions

(2021) Kelly M. Girskis et al.   NEURON

A eutherian-specific microRNA controls the translation of Satb2 in a model of cortical differentiation

(2021) Manuella Martins et al.   Stem Cell Reports

H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion

(2021) Cemil Kerimoglu et al.   Science Advances

Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution

(2020) Annalisa Paolino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Granules: A View from the RNA Perspective

(2020) Siran Tian et al.   MOLECULES

Variations of telencephalic development that paved the way for neocortical evolution

(2020) Fernando García-Moreno et al.   PROGRESS IN NEUROBIOLOGY

Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset

(2020) Michael Heide et al.   SCIENCE

Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion

(2020) Barbara K. Stepien et al.   CURRENT BIOLOGY

Repression of Irs2 by let‐7 mi RNA s is essential for homeostasis of the telencephalic neuroepithelium

(2020) Virginia Fernández et al.   EMBO JOURNAL

Metabolic Regulation of Neocortical Expansion in Development and Evolution

(2020) Takashi Namba et al.   NEURON

Massively parallel discovery of human-specific substitutions that alter enhancer activity

(2020) Severin Uebbing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding mixed messages in the developing cortex: translational regulation of neural progenitor fate

(2020) Mariah L Hoye et al.   CURRENT OPINION IN NEUROBIOLOGY

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex

(2019) L. Telley et al.   SCIENCE

A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation

(2019) Damon Polioudakis et al.   NEURON

The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine–containing mRNAs

(2019) Phillip J. Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

(2019) Jernej Ule et al.   MOLECULAR CELL

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

(2018) Adrián Cárdenas et al.   CELL

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation

(2018) Ikuo K. Suzuki et al.   CELL

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis

(2018) Ian T. Fiddes et al.   CELL

Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain

(2018) Wataru Yamashita et al.   DEVELOPMENT

Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence

(2018) Heather Chapman et al.   DEVELOPMENTAL BIOLOGY

Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence

(2018) Ki-Jun Yoon et al.   JOURNAL OF CELL BIOLOGY

Cortical progenitor biology: key features mediating proliferation versus differentiation

(2018) Ana Uzquiano et al.   JOURNAL OF NEUROCHEMISTRY

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex

(2018) Marta Florio et al.   eLife

Epitranscriptomics: A New Regulatory Mechanism of Brain Development and Function

(2018) Florian Noack et al.   Frontiers in Neuroscience

Histone Modifications: Insights into Their Influence on Gene Expression

(2018) Bruce Stillman   CELL

Clonal analysis reveals laminar fate multipotency and daughter cell apoptosis of mouse cortical intermediate progenitors

(2018) Anca B. Mihalas et al.   DEVELOPMENT

A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex

(2018) Samir Vaid et al.   DEVELOPMENT

A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum

(2018) Rodrigo Suárez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

(2018) Gina E. Elsen et al.   Frontiers in Neuroscience

Post-transcriptional control of miRNA biogenesis

(2018) Gracjan Michlewski et al.   RNA

Homology, neocortex, and the evolution of developmental mechanisms

(2018) Steven D. Briscoe et al.   SCIENCE

Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

(2018) Nereo Kalebic et al.   eLife

RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development

(2017) Ashley L. Lennox et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Topologically associated domains: a successful scaffold for the evolution of gene regulation in animals

(2017) Rafael D. Acemel et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Progressive Loss of Function in a Limb Enhancer during Snake Evolution

(2016) Evgeny Z. Kvon et al.   CELL

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

(2016) Tomoki Otani et al.   Cell Stem Cell

Human adaptation and evolution by segmental duplication

(2016) Megan Y Dennis et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cerebral cortex expansion and folding: what have we learned?

(2016) Virginia Fernández et al.   EMBO JOURNAL

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

(2016) Yi-Chuan Chen et al.   NATURE NEUROSCIENCE

The origin and evolution of cell types

(2016) Detlev Arendt et al.   NATURE REVIEWS GENETICS

The neurogenetics of alternative splicing

(2016) Celine K. Vuong et al.   NATURE REVIEWS NEUROSCIENCE

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses

(2016) Matteo Fossati et al.   NEURON

A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA

(2016) Neha Rani et al.   NEURON

Birds have primate-like numbers of neurons in the forebrain

(2016) Seweryn Olkowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory Enhancer–Core-Promoter Communication via Transcription Factors and Cofactors

(2016) Muhammad A. Zabidi et al.   TRENDS IN GENETICS

On TADs and LADs: Spatial Control Over Gene Expression

(2016) Adriana Gonzalez-Sandoval et al.   TRENDS IN GENETICS

A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels

(2016) Maria Ángeles Martínez-Martínez et al.   Nature Communications

An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals

(2016) Tomohisa Toda et al.   Scientific Reports

Analysis of spatial-temporal gene expression patterns reveals dynamics and regionalization in developing mouse brain

(2016) Shen-Ju Chou et al.   Scientific Reports

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity

(2016) Anca B. Mihalas et al.   Cell Reports

The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

(2016) Xiang-Chun Ju et al.   eLife

Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development

(2016) Felipe Mora-Bermúdez et al.   eLife

A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification

(2016) M. Florio et al.   Science Advances

Pluripotency and the endogenous retrovirus HERVH: Conflict or serendipity?

(2015) Zsuzsanna Izsvák et al.   BIOESSAYS

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

Human-Chimpanzee Differences in a FZD8 Enhancer Alter Cell-Cycle Dynamics in the Developing Neocortex

(2015) J. Lomax Boyd et al.   CURRENT BIOLOGY

Long non‐coding RNAs in corticogenesis: deciphering the non‐coding code of the brain

(2015) Julieta Aprea et al.   EMBO JOURNAL

MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

(2015) Emily Sun et al.   EXPERIMENTAL NEUROLOGY

Transcriptional and epigenetic mechanisms of early cortical development: An examination of how Pax6 coordinates cortical development

(2015) Athéna R. Ypsilanti et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Evolutionary origin of Tbr2-expressing precursor cells and the subventricular zone in the developing cortex

(2015) Verónica Martínez-Cerdeño et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Accelerated Evolution of Enhancer Hotspots in the Mammal Ancestor

(2015) Alisha K. Holloway et al.   MOLECULAR BIOLOGY AND EVOLUTION

Fixed single-cell transcriptomic characterization of human radial glial diversity

(2015) Elliot R Thomsen et al.   NATURE METHODS

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

(2015) Lea Chia-Ling Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

(2015) J. Gray Camp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

(2015) M. Florio et al.   SCIENCE

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

(2015) Martine N. Manuel et al.   Frontiers in Cellular Neuroscience

Pathophysiological analyses of cortical malformation using gyrencephalic mammals

(2015) Kosuke Masuda et al.   Scientific Reports

Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex

(2015) Fong Kuan Wong et al.   PLOS BIOLOGY

Nucleosome Structure and Function

(2014) Robert K. McGinty et al.   CHEMICAL REVIEWS

Exploring the genesis and functions of Human Accelerated Regions sheds light on their role in human evolution

(2014) Melissa J Hubisz et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Neural progenitors, neurogenesis and the evolution of the neocortex

(2014) M. Florio et al.   DEVELOPMENT

The case for DUF1220 domain dosage as a primary contributor to anthropoid brain expansion

(2014) Jonathon G. Keeney et al.   Frontiers in Human Neuroscience

Palindromic GOLGA8 core duplicons promote chromosome 15q13.3 microdeletion and evolutionary instability

(2014) Francesca Antonacci et al.   NATURE GENETICS

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

Novel Primate miRNAs Coevolved with Ancient Target Genes in Germinal Zone-Specific Expression Patterns

(2014) Mary L. Arcila et al.   NEURON

Growth of the Developing Cerebral Cortex Is Controlled by MicroRNA-7 through the p53 Pathway

(2014) Andrew Pollock et al.   Cell Reports

The Evolutions of Large Brain Size in Mammals: The ‘Over-700-Gram Club Quartet'

(2013) Paul R. Manger et al.   BRAIN BEHAVIOR AND EVOLUTION

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

Fine-Tuning of Neurogenesis is Essential for the Evolutionary Expansion of the Cerebral Cortex

(2013) Sylvie Poluch et al.   CEREBRAL CORTEX

Regulation of cerebral cortex size and folding by expansion of basal progenitors

(2013) Miki Nonaka-Kinoshita et al.   EMBO JOURNAL

Evolution and diversity of copy number variation in the great ape lineage

(2013) P. H. Sudmant et al.   GENOME RESEARCH

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

The complete genome sequence of a Neanderthal from the Altai Mountains

(2013) Kay Prüfer et al.   NATURE

New genes as drivers of phenotypic evolution

(2013) Sidi Chen et al.   NATURE REVIEWS GENETICS

Human brain evolution: transcripts, metabolites and their regulators

(2013) Mehmet Somel et al.   NATURE REVIEWS NEUROSCIENCE

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

Many human accelerated regions are developmental enhancers

(2013) J. A. Capra et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type

(2013) Gregor-Alexander Pilz et al.   Nature Communications

Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex

(2013) Bridget E. LaMonica et al.   Nature Communications

Changes in the regulation of cortical neurogenesis contribute to encephalization during amniote brain evolution

(2013) Tadashi Nomura et al.   Nature Communications

Evolutionary History and Genome Organization of DUF1220 Protein Domains

(2013) Majesta S. O’Bleness et al.   G3-Genes Genomes Genetics

Copy-number changes in evolution: rates, fitness effects and adaptive significance

(2013) Vaishali Katju et al.   Frontiers in Genetics

Inhibition of SRGAP2 Function by Its Human-Specific Paralogs Induces Neoteny during Spine Maturation

(2012) Cécile Charrier et al.   CELL

Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication

(2012) Megan Y. Dennis et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

An Asymmetrically Localized Staufen2-Dependent RNA Complex Regulates Maintenance of Mammalian Neural Stem Cells

(2012) John P. Vessey et al.   Cell Stem Cell

The Temporal Sequence of the Mammalian Neocortical Neurogenetic Program Drives Mediolateral Pattern in the Chick Pallium

(2012) Ikuo K. Suzuki et al.   DEVELOPMENTAL CELL

Hi–C: A comprehensive technique to capture the conformation of genomes

(2012) Jon-Matthew Belton et al.   METHODS

A Recent Evolutionary Change Affects a Regulatory Element in the Human FOXP2 Gene

(2012) Tomislav Maricic et al.   MOLECULAR BIOLOGY AND EVOLUTION

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells

(2012) Yusuke Kishi et al.   NATURE NEUROSCIENCE

Revising the human mutation rate: implications for understanding human evolution

(2012) Aylwyn Scally et al.   NATURE REVIEWS GENETICS

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

Analysis of Human Accelerated DNA Regions Using Archaic Hominin Genomes

(2012) Hernán A. Burbano et al.   PLoS One

Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal

(2012) S. A. Fietz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues

(2012) J. Merkin et al.   SCIENCE

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Germinal Zones in the Developing Cerebral Cortex of Ferret: Ontogeny, Cell Cycle Kinetics, and Diversity of Progenitors

(2011) Isabel Reillo et al.   CEREBRAL CORTEX

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex

(2011) M. Asami et al.   DEVELOPMENT

Human-specific loss of regulatory DNA and the evolution of human-specific traits

(2011) Cory Y. McLean et al.   NATURE

A new subtype of progenitor cell in the mouse embryonic neocortex

(2011) Xiaoqun Wang et al.   NATURE NEUROSCIENCE

Accelerated Recruitment of New Brain Development Genes into the Human Genome

(2011) Yong E. Zhang et al.   PLOS BIOLOGY

A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex

(2010) Isabel Reillo et al.   CEREBRAL CORTEX

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

Contrasts between adaptive coding and noncoding changes during human evolution

(2010) Ralph Haygood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of Human Copy Number Variation and Multicopy Genes

(2010) Peter H. Sudmant et al.   SCIENCE

Cell cycle control of mammalian neural stem cells: putting a speed limit on G1

(2010) Paolo Salomoni et al.   TRENDS IN CELL BIOLOGY

Evolution of the mutation rate

(2010) Michael Lynch   TRENDS IN GENETICS

Chromosomal Redistribution of Male-Biased Genes in Mammalian Evolution with Two Bursts of Gene Gain on the X Chromosome

(2010) Yong E. Zhang et al.   PLOS BIOLOGY

A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

(2009) Wolfgang Enard et al.   CELL

Retinoic Acid from the Meninges Regulates Cortical Neuron Generation

(2009) Julie A. Siegenthaler et al.   CELL

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Dynamic regulation of Notch signaling in neural progenitor cells

(2009) Ryoichiro Kageyama et al.   CURRENT OPINION IN CELL BIOLOGY

The human brain in numbers: a linearly scaled-up primate brain

(2009) Suzana Herculano-Houzel   Frontiers in Human Neuroscience

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A burst of segmental duplications in the genome of the African great ape ancestor

(2009) Tomas Marques-Bonet et al.   NATURE

Human-specific transcriptional regulation of CNS development genes by FOXP2

(2009) Genevieve Konopka et al.   NATURE

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

(2009) Chunnian Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fgf10 Regulates Transition Period of Cortical Stem Cell Differentiation to Radial Glia Controlling Generation of Neurons and Basal Progenitors

(2009) Setsuko Sahara et al.   NEURON

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

(2009) Stephen N. Sansom et al.   PLoS Genetics

Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution

(2008) Sean B. Carroll   CELL

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

(2008) D. De Pietri Tonelli et al.   DEVELOPMENT

Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities

(2008) Nicola Brunetti-Pierri et al.   NATURE GENETICS

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON