The RNA-Binding Protein HuD Regulates Alternative Splicing and Alternative Polyadenylation in the Mouse Neocortex

Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain

(2020) Angela Mathison et al.   PLoS One

ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue

(2020) Judit Carrasco et al.   MOLECULAR CELL

Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3′ UTR Landscape in Drosophila

(2020) Lu Wei et al.   MOLECULAR CELL

Tissue-specific mechanisms of alternative polyadenylation: Testis, brain, and beyond (2018 update)

(2019) Clinton C. MacDonald   Wiley Interdisciplinary Reviews-RNA

Roles of Primary Cilia in the Developing Brain

(2019) Sang Min Park et al.   Frontiers in Cellular Neuroscience

Loss of EPAC2 alters dendritic spine morphology and inhibitory synapse density

(2019) Kelly A. Jones et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses

(2019) Muhammad Irfan et al.   Scientific Reports

Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth

(2019) Zhiping Zhang et al.   Cell Reports

PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing

(2019) Christina J Herrmann et al.   NUCLEIC ACIDS RESEARCH

Neuronal functions of adaptor complexes involved in protein sorting

(2018) Carlos M Guardia et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuronal RNA-binding protein HuD regulates addiction-related gene expression and behavior

(2018) R. J. Oliver et al.   GENES BRAIN AND BEHAVIOR

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

Cbx3 maintains lineage specificity during neural differentiation

(2017) Chengyang Huang et al.   GENES & DEVELOPMENT

The contribution of alternative splicing to genetic risk for psychiatric disorders

(2017) E. Reble et al.   GENES BRAIN AND BEHAVIOR

MultiQC: summarize analysis results for multiple tools and samples in a single report

(2016) Philip Ewels et al.   BIOINFORMATICS

Structure and functional roles of Epac2 (Rapgef4)

(2016) Kenji Sugawara et al.   GENE

ALG6-CDG: a recognizable phenotype with epilepsy, proximal muscle weakness, ataxia and behavioral and limb anomalies

(2016) Eva Morava et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Distal Alternative Last Exons Localize mRNAs to Neural Projections

(2016) J. Matthew Taliaferro et al.   MOLECULAR CELL

The neurogenetics of alternative splicing

(2016) Celine K. Vuong et al.   NATURE REVIEWS NEUROSCIENCE

IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders

(2016) Jaeseung Kang et al.   NEUROPHARMACOLOGY

Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia

(2016) Vilte E. Barakauskas et al.   SCHIZOPHRENIA RESEARCH

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

(2016) Claudia Scheckel et al.   eLife

Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering

(2015) M. Hashim Raza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alternative polyadenylation in the nervous system: To what lengths will 3′ UTR extensions take us?

(2014) Pedro Miura et al.   BIOESSAYS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Up-regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex

(2014) Hiroaki Oshiro et al.   GENES TO CELLS

Prenatal Deletion of the RNA-Binding Protein HuD Disrupts Postnatal Cortical Circuit Maturation and Behavior

(2014) E. M. DeBoer et al.   JOURNAL OF NEUROSCIENCE

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Somatic deletions implicated in functional diversity of brain cells of individuals with schizophrenia and unaffected controls

(2014) Junho Kim et al.   Scientific Reports

Mutations in CSPP1 Lead to Classical Joubert Syndrome

(2013) Naiara Akizu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in CSPP1, Encoding a Core Centrosomal Protein, Cause a Range of Ciliopathy Phenotypes in Humans

(2013) Ranad Shaheen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice

(2013) Ian J. Orozco et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alternative cleavage and polyadenylation: extent, regulation and function

(2013) Ran Elkon et al.   NATURE REVIEWS GENETICS

HuD Promotes BDNF Expression in Brain Neurons via Selective Stabilization of the BDNF Long 3′UTR mRNA

(2013) Megan Allen et al.   PLoS One

DNA Methylation of Alternative Promoters Directs Tissue Specific Expression of Epac2 Isoforms

(2013) Erling A. Hoivik et al.   PLoS One

Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction

(2013) L. M. Bronicki et al.   RNA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

CBX3 regulates efficient RNA processing genome-wide

(2012) A. Smallwood et al.   GENOME RESEARCH

A quantitative atlas of polyadenylation in five mammals

(2012) Adnan Derti et al.   GENOME RESEARCH

Social, Communication, and Cortical Structural Impairments in Epac2-Deficient Mice

(2012) D. P. Srivastava et al.   JOURNAL OF NEUROSCIENCE

A clinical and gene analysis of late-onset combined methylmalonic aciduria and homocystinuria, cblC type, in China

(2012) Xianling Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neurology of inherited glycosylation disorders

(2012) Hudson H Freeze et al.   LANCET NEUROLOGY

Activity-Mediated AMPA Receptor Remodeling, Driven by Alternative Splicing in the Ligand-Binding Domain

(2012) Andrew C. Penn et al.   NEURON

Neuronal Elav-like (Hu) Proteins Regulate RNA Splicing and Abundance to Control Glutamate Levels and Neuronal Excitability

(2012) Gulayse Ince-Dunn et al.   NEURON

Activity-regulated RNA editing in select neuronal subfields in hippocampus

(2012) Ales Balik et al.   NUCLEIC ACIDS RESEARCH

An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice

(2012) Deepak P. Srivastava et al.   PLOS BIOLOGY

The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain

(2012) Amanda Wright et al.   Frontiers in Molecular Neuroscience

Alternative Splicing of AMPA Subunits in Prefrontal Cortical Fields of Cynomolgus Monkeys Following Chronic Ethanol Self-Administration

(2012) Glen Acosta et al.   Frontiers in Psychiatry

Adaptor Protein Complex 4 Deficiency Causes Severe Autosomal-Recessive Intellectual Disability, Progressive Spastic Paraplegia, Shy Character, and Short Stature

(2011) Rami Abou Jamra et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders

(2011) Stephen J. Glatt et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Regional and developmental brain expression patterns of SNAP25 splice variants

(2011) Gerald R Prescott et al.   BMC NEUROSCIENCE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation

(2011) Kyle D. Mansfield et al.   NUCLEIC ACIDS RESEARCH

Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner

(2011) H.-L. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

DTNBP1 (dysbindin) gene variants modulate prefrontal brain function in schizophrenic patients - support for the glutamate hypothesis of schizophrenias

(2010) A. J. Fallgatter et al.   GENES BRAIN AND BEHAVIOR

Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and intellectual disability

(2010) A. Moreno-De-Luca et al.   JOURNAL OF MEDICAL GENETICS

CSPP Is a Ciliary Protein Interacting with Nephrocystin 8 and Required for Cilia Formation

(2010) Sebastian Patzke et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)

(2010) A. G. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flip and Flop: A Molecular Determinant for AMPA Receptor Channel Opening†

(2009) Weimin Pei et al.   BIOCHEMISTRY

Centrosome/Spindle Pole–associated Protein Regulates Cytokinesis via Promoting the Recruitment of MyoGEF to the Central Spindle

(2009) Michael Asiedu et al.   MOLECULAR BIOLOGY OF THE CELL

Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets

(2009) Federico Bolognani et al.   NUCLEIC ACIDS RESEARCH

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD

(2008) Daniel C. Tanner et al.   HIPPOCAMPUS

The SNAP-25 Linker as an Adaptation Toward Fast Exocytosis

(2008) Gábor Nagy et al.   MOLECULAR BIOLOGY OF THE CELL

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

A General Definition and Nomenclature for Alternative Splicing Events

(2008) Michael Sammeth et al.   PLoS Computational Biology

An Ancient Duplication of Exon 5 in the Snap25 Gene Is Required for Complex Neuronal Development/Function

(2008) Jenny U. Johansson et al.   PLoS Genetics

RNA–protein interactions and control of mRNA stability in neurons

(2007) Federico Bolognani et al.   JOURNAL OF NEUROSCIENCE RESEARCH