Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence

The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

(2018) Luis de la Torre-Ubieta et al.   CELL

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

(2018) Suijuan Zhong et al.   NATURE

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

(2018) Yang Wang et al.   NATURE NEUROSCIENCE

A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

(2018) Siraj K. Zahr et al.   NEURON

Epitranscriptomic m 6 A Regulation of Axon Regeneration in the Adult Mammalian Nervous System

(2018) Yi-Lan Weng et al.   NEURON

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

(2017) Hua-Bing Li et al.   NATURE

m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

(2017) Boxuan Simen Zhao et al.   NATURE

RNA modifications and structures cooperate to guide RNA–protein interactions

(2017) Cole J.T. Lewis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

(2017) Steven A. Sloan et al.   NEURON

Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex

(2017) Tomasz J. Nowakowski et al.   SCIENCE

Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex

(2017) Chongyuan Luo et al.   SCIENCE

ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells

(2017) Horng D. Ou et al.   SCIENCE

Single-Cell Multiomics: Multiple Measurements from Single Cells

(2017) Iain C. Macaulay et al.   TRENDS IN GENETICS

Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

(2017) Xuekun Li et al.   Nature Communications

Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9

(2017) Peiwu Qin et al.   Nature Communications

DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress

(2017) Bing Yao et al.   Nature Communications

DNA Methylome Analysis Identifies Transcription Factor-Based Epigenomic Signatures of Multilineage Competence in Neural Stem/Progenitor Cells

(2017) Tsukasa Sanosaka et al.   Cell Reports

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders

(2017) Godwin Sokpor et al.   Frontiers in Molecular Neuroscience

Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility

(2017) Joana V. Flores et al.   Stem Cell Reports

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Single-cell triple omics sequencing reveals genetic, epigenetic and transcriptomic heterogeneity in hepatocellular carcinomas

(2016) Yu Hou et al.   CELL RESEARCH

Modeling psychiatric disorders with patient-derived iPSCs

(2016) Zhexing Wen et al.   CURRENT OPINION IN NEUROBIOLOGY

ATP-dependent chromatin remodeling during mammalian development

(2016) Swetansu K. Hota et al.   DEVELOPMENT

Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning

(2016) Tran Tuoc et al.   MOLECULAR NEUROBIOLOGY

Chromosome conformation elucidates regulatory relationships in developing human brain

(2016) Hyejung Won et al.   NATURE

DNA methylation on N6-adenine in mammalian embryonic stem cells

(2016) Tao P. Wu et al.   NATURE

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

(2016) Alistair N. Boettiger et al.   NATURE

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic mechanisms in neurogenesis

(2016) Bing Yao et al.   NATURE REVIEWS NEUROSCIENCE

Transcriptome-wide distribution and function of RNA hydroxymethylcytosine

(2016) B. Delatte et al.   SCIENCE

Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex

(2016) L. Telley et al.   SCIENCE

Messenger RNA modifications: Form, distribution, and function

(2016) W. V. Gilbert et al.   SCIENCE

mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium

(2016) Christina Bachmann et al.   PLoS Genetics

Chromatin-Remodeling-Factor ARID1B Represses Wnt/β-Catenin Signaling

(2015) Georgia Vasileiou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Adenine Code for DNA: A Second Life for N6-Methyladenine

(2015) Holger Heyn et al.   CELL

DNA Methylation on N6-Adenine in C. elegans

(2015) Eric Lieberman Greer et al.   CELL

N6-Methyladenine DNA Modification in Drosophila

(2015) Guoqiang Zhang et al.   CELL

N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas

(2015) Ye Fu et al.   CELL

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis

(2015) Jaehoon Shin et al.   Cell Stem Cell

Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

(2015) Assaf Rotem et al.   NATURE BIOTECHNOLOGY

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

(2015) Matthew B Johnson et al.   NATURE NEUROSCIENCE

The Outer Subventricular Zone and Primate-Specific Cortical Complexification

(2015) Colette Dehay et al.   NEURON

Attomole quantification and global profile of RNA modifications: Epitranscriptome of human neural stem cells

(2015) Maria Basanta-Sanchez et al.   NUCLEIC ACIDS RESEARCH

Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing

(2015) D. A. Cusanovich et al.   SCIENCE

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Methyl-CpG-binding domain proteins: readers of the epigenome

(2015) Qian Du et al.   Epigenomics

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

(2014) Hao Wu et al.   CELL

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

(2014) Pedro J. Batista et al.   Cell Stem Cell

The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development

(2014) N. Morimoto-Suzki et al.   DEVELOPMENT

Emerging Concept in DNA Methylation: Role of Transcription Factors in Shaping DNA Methylation Patterns

(2014) Claire Marchal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival

(2014) L. A. Watson et al.   JOURNAL OF NEUROSCIENCE

Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

(2014) Alex A Pollen et al.   NATURE BIOTECHNOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity

(2014) Sébastien A Smallwood et al.   NATURE METHODS

Decoding neural transcriptomes and epigenomes via high-throughput sequencing

(2014) Jaehoon Shin et al.   NATURE NEUROSCIENCE

An eIF4E1/4E-T Complex Determines the Genesis of Neurons from Precursors by Translationally Repressing a Proneurogenic Transcription Program

(2014) Guang Yang et al.   NEURON

Neural Stem Cell Differentiation Is Dictated by Distinct Actions of Nuclear Receptor Corepressors and Histone Deacetylases

(2014) Gonçalo Castelo-Branco et al.   Stem Cell Reports

Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment

(2013) Jennifer E. Phillips-Cremins et al.   CELL

BAF chromatin remodeling complex: Cortical size regulation and beyond

(2013) Tran Cong Tuoc et al.   CELL CYCLE

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

(2013) Run-Rui Zhang et al.   Cell Stem Cell

Creating a neural specific chromatin landscape by npBAF and nBAF complexes

(2013) Brett T Staahl et al.   CURRENT OPINION IN NEUROBIOLOGY

Mechanisms of astrocytogenesis in the mammalian brain

(2013) Masakazu Namihira et al.   CURRENT OPINION IN NEUROBIOLOGY

Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness

(2013) Tran Cong Tuoc et al.   DEVELOPMENTAL CELL

Role of miRNAs and epigenetics in neural stem cell fate determination

(2013) Miguel Alejandro Lopez-Ramirez et al.   Epigenetics

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

(2013) Junjie U Guo et al.   NATURE NEUROSCIENCE

Chromatin modifiers and remodellers: regulators of cellular differentiation

(2013) Taiping Chen et al.   NATURE REVIEWS GENETICS

Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis

(2013) Nunung Yuniarti et al.   NEUROSCIENCE RESEARCH

Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains

(2013) Shin-ichiro Takebayashi et al.   Epigenetics & Chromatin

Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis

(2013) Maria A. Hahn et al.   Cell Reports

Transcription Factor Occupancy Can Mediate Active Turnover of DNA Methylation at Regulatory Regions

(2013) Angelika Feldmann et al.   PLoS Genetics

DNA methylation presents distinct binding sites for human transcription factors

(2013) Shaohui Hu et al.   eLife

Mutations in NSUN2 Cause Autosomal- Recessive Intellectual Disability

(2012) Lia Abbasi-Moheb et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

(2012) Yufei Xu et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

MicroRNAs tune cerebral cortical neurogenesis

(2012) M-L Volvert et al.   CELL DEATH AND DIFFERENTIATION

Whole exome sequencing identifies a splicing mutation inNSUN2as a cause of a Dubowitz-like syndrome

(2012) Fernando Jose Martinez et al.   JOURNAL OF MEDICAL GENETICS

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex

(2012) S. J. Franco et al.   SCIENCE

CTCF Is Required for Neural Development and Stochastic Expression of Clustered Pcdh Genes in Neurons

(2012) Teruyoshi Hirayama et al.   Cell Reports

Chromatin “pre-pattern” and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm

(2012) Cheng-Ran Xu et al.   Nucleus

Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond

(2011) Junjie U. Guo et al.   CELL CYCLE

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

(2011) Diana C Hargreaves et al.   CELL RESEARCH

Epigenetic regulation of neurogenesis in the adult mammalian brain

(2011) Jiaqi Sun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Fibroblast growth factor 2 regulates astrocyte differentiation in a region-specific manner in the hindbrain

(2011) Krithi Irmady et al.   GLIA

Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX

(2011) W. Niu et al.   JOURNAL OF NEUROSCIENCE

esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function

(2011) Lena Ho et al.   NATURE CELL BIOLOGY

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development

(2011) X. Zhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CBP Histone Acetyltransferase Activity Regulates Embryonic Neural Differentiation in the Normal and Rubinstein-Taybi Syndrome Brain

(2010) Jing Wang et al.   DEVELOPMENTAL CELL

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Epigenetic choreographers of neurogenesis in the adult mammalian brain

(2010) Dengke K Ma et al.   NATURE NEUROSCIENCE

Epigenetic control of neural precursor cell fate during development

(2010) Yusuke Hirabayashi et al.   NATURE REVIEWS NEUROSCIENCE

Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

(2010) J. D. Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

ATP-dependent chromatin remodeling in neural development

(2009) Andrew S Yoo et al.   CURRENT OPINION IN NEUROBIOLOGY

Committed Neuronal Precursors Confer Astrocytic Potential on Residual Neural Precursor Cells

(2009) Masakazu Namihira et al.   DEVELOPMENTAL CELL

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition

(2009) Yusuke Hirabayashi et al.   NEURON

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

(2009) R. L. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

(2009) L. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell

Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development

(2008) Jessica L. MacDonald et al.   DEVELOPMENTAL DYNAMICS

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

An intrinsic mechanism of corticogenesis from embryonic stem cells

(2008) Nicolas Gaspard et al.   NATURE

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON

Polycomb Group Genes: Keeping Stem Cell Activity in Balance

(2008) Martin Sauvageau et al.   PLOS BIOLOGY