The IL-2A receptor pathway and its role in lymphocyte differentiation and function
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The IL-2A receptor pathway and its role in lymphocyte differentiation and function
Authors
Keywords
-
Journal
CYTOKINE & GROWTH FACTOR REVIEWS
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2022-07-02
DOI
10.1016/j.cytogfr.2022.06.004
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mathematical Modeling of Proliferative Immune Response Initiated by Interactions Between Classical Antigen-Presenting Cells Under Joint Antagonistic IL-2 and IL-4 Signaling
- (2022) Komlan Atitey et al. Frontiers in Molecular Biosciences
- Facile discovery of surrogate cytokine agonists
- (2022) Michelle Yen et al. CELL
- sIL-2R: A Novel Diagnostic Biomarker for Primary Adrenal Lymphoma
- (2022) Kai Yu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Human IL-2Rɑ subunit binding modulation of IL-2 through a decline in electrostatic interactions: A computational and experimental approach
- (2022) Arezoo Beig Parikhani et al. PLoS One
- Soluble interleukin-2 receptor serum levels facilitate prediction of relapses in subgroups of patients with juvenile idiopathic arthritis
- (2022) Linda Ziegler et al. RHEUMATOLOGY
- IL-2 complex recovers steroid-induced inhibition in immunochemotherapy for head and neck cancer
- (2022) Michihisa Kono et al. Translational Oncology
- Efficacy and antitumor activity of a mutant type of interleukin 2
- (2022) Rada Dehghan et al. Scientific Reports
- Pleural Fluid Soluble Interleukin-2 Receptor as a Biomarker for the Diagnosis of Tuberculosis Pleural Effusion: A Systematic Review and Meta-Analysis
- (2022) Zhi Yan et al. Journal of Tropical Medicine
- NK/T cell ratios associate with interleukin-2 receptor alpha chain expression and shedding in multiple sclerosis
- (2021) Max Mimpen et al. JOURNAL OF NEUROIMMUNOLOGY
- Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation, innate immunity hyperactivation, and organ damage in COVID-19 pneumonia
- (2021) Luca Quartuccio et al. CYTOKINE
- Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development
- (2021) Heng Zhang et al. Cell Reports
- New Tool for Rapid and Accurate Detection of Interleukin-2 and Soluble Interleukin-2 Receptor α in Cancer Diagnosis Using a Bioresponsive Microgel and Multivalent Protein Binding
- (2021) Hae Min Yang et al. ACS Applied Materials & Interfaces
- Engineering a safe monoclonal anti‐human IL‐2 that is effective in a murine model of food allergy and asthma
- (2021) Martin Klein et al. ALLERGY
- Predictive Immunological, Virological, and Routine Laboratory Markers for Critical COVID-19 on Admission
- (2021) Mercedes García-Gasalla et al. Canadian Journal of Infectious Diseases & Medical Microbiology
- A biomarker-guided, prospective, phase 2 trial of pre-emptive graft-versus-host disease therapy using anti-thymocyte globulin
- (2021) Rutvij A. Khanolkar et al. CYTOTHERAPY
- Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis
- (2021) Chuan Zhang et al. Cancer Medicine
- Biomarkers of systemic inflammation, soluble IL-2Rα and the multiple sclerosis-associated IL2RA SNP rs2104286 in healthy subjects and multiple sclerosis patients
- (2021) Sophie Buhelt et al. Multiple Sclerosis and Related Disorders
- IL2RA Methylation and Gene Expression in Relation to the Multiple Sclerosis-Associated Gene Variant rs2104286 and Soluble IL-2Rα in CD8+ T Cells
- (2021) Sophie Buhelt et al. Frontiers in Immunology
- Association of high serum soluble interleukin 2 receptor levels with risk of adverse events in cardiac sarcoidosis
- (2021) Yuta Kobayashi et al. ESC Heart Failure
- Nanoparticle delivery of recombinant IL-2 (BALLkine-2) achieves durable tumor control with less systemic adverse effects in cancer immunotherapy
- (2021) Jun Kim et al. BIOMATERIALS
- Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study
- (2021) Benjamin I. Perry et al. BRAIN BEHAVIOR AND IMMUNITY
- Role of immune mediators in predicting hospitalization of SARS-CoV-2 positive patients
- (2021) S. Ashrafzadeh-Kian et al. CYTOKINE
- Controlled release of bioactive IL-2 from visible light photocured biodegradable elastomers for cancer immunotherapy applications
- (2021) Mohamed A. Shaker et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Anti-pituitary and anti-hypothalamus autoantibody associations with inflammation and hypogonadotropic hypogonadism in men with traumatic brain injury
- (2020) Sushupta Vijapur et al. JOURNAL OF NEUROTRAUMA
- Inflammatory activation and endothelial dysfunction markers in patients with permanent atrial fibrillation: a cross-sectional study
- (2020) Carlo Domenico Maida et al. Aging-US
- Serum levels of selected cytokines and soluble adhesion molecules in acute myeloid leukemia: Soluble receptor for interleukin-2 predicts overall survival
- (2020) Tomas Kupsa et al. CYTOKINE
- Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke
- (2020) Pengfei Yang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Association of soluble interleukin‐2 receptor α and tumour necrosis factor receptor 1 with heart failure: The Multi‐Ethnic Study of Atherosclerosis
- (2020) Hooman Bakhshi et al. ESC Heart Failure
- BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
- (2020) Francis M. Grant et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Foxp3: a genetic foundation for regulatory T cell differentiation and function
- (2020) Fred Ramsdell et al. NATURE IMMUNOLOGY
- Soluble IL-2Rα correlates with imbalances of Th1/Th2 and Tc1/Tc2 cells in patients with acute brucellosis
- (2020) Hua-Li Sun et al. Infectious Diseases of Poverty
- The IL-2 – IL-2 receptor pathway in health and disease: The role of the soluble IL-2 receptor
- (2020) Jan Damoiseaux CLINICAL IMMUNOLOGY
- T cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice
- (2020) Genevieve N. Mullins et al. Scientific Reports
- Expression of a Functional IL-2 Receptor in Vascular Smooth Muscle Cells
- (2019) Prakash Arumugam et al. JOURNAL OF IMMUNOLOGY
- Microenvironment tailors nTreg structure and function
- (2019) Valérie Schiavon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of inflammatory and vascular markers associated with mild cognitive impairment
- (2019) Xue-Ning Shen et al. Aging-US
- A Rapid Colorimetric Sensor for Soluble Interleukin‐2 Receptor α, Based on Aptamer‐Adsorbed AuNP
- (2019) Jinseong Jeon et al. CHEMBIOCHEM
- Inflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study
- (2019) Haidong Lu et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Biomarkers of Progression after HIV Acute/Early Infection: Nothing Compares to CD4+ T-cell Count?
- (2018) Gabriela Turk et al. Viruses-Basel
- A Multiple Biomarker Approach in Patients with Cardiac Sarcoidosis
- (2018) Takatoyo Kiko et al. International Heart Journal
- IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level
- (2017) Byron B. Au-Yeung et al. JOURNAL OF IMMUNOLOGY
- Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas
- (2016) Eric T. Wong et al. BMC CANCER
- CD8 + T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure
- (2016) David M. Gravano et al. JOURNAL OF AUTOIMMUNITY
- Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets
- (2016) Kevin H. Toomer et al. JOURNAL OF IMMUNOLOGY
- Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity
- (2016) Chong T. Luo et al. NATURE
- Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8+ T Lymphocyte Fates
- (2016) Patrick J. Metz et al. Scientific Reports
- Plasma Levels of Soluble Interleukin-2 Receptor αSignificance
- (2015) Peter Durda et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow
- (2015) Jaeyop Lee et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Inducible Costimulator Augments Tc17 Cell Responses to Self and Tumor Tissue
- (2015) Michelle H. Nelson et al. JOURNAL OF IMMUNOLOGY
- Regulation of Asymmetric Division and CD8+T Lymphocyte Fate Specification by Protein Kinase Cζ and Protein Kinase Cλ/ι
- (2015) Patrick J. Metz et al. JOURNAL OF IMMUNOLOGY
- Elevated soluble IL-2Rα, IL-8, and MIP-1β levels are associated with inferior outcome and are independent of MIPI score in patients with mantle cell lymphoma
- (2014) Mohamad B. Sonbol et al. AMERICAN JOURNAL OF HEMATOLOGY
- Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool
- (2014) J. Christoph Vahl et al. IMMUNITY
- Cutting Edge: CD4+ T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8+ T Cell Responses
- (2014) E. B. Wilson et al. JOURNAL OF IMMUNOLOGY
- Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses
- (2014) Janilyn Arsenio et al. NATURE IMMUNOLOGY
- Continuous requirement for the TCR in regulatory T cell function
- (2014) Andrew G Levine et al. NATURE IMMUNOLOGY
- Inflammation Enhances IL-2 Driven Differentiation of Cytolytic CD4 T Cells
- (2014) Aspen M. Workman et al. PLoS One
- Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy
- (2013) Wei Liao et al. IMMUNITY
- CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
- (2013) Kate S. Smigiel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development
- (2013) Kenjiro Fujimura et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’
- (2012) Aron M. Levin et al. NATURE
- Cytokine Profiles, CTL Response and T Cell Frequencies in the Peripheral Blood of Acute Patients and Individuals Recovered from Hepatitis E Infection
- (2012) Anuradha S. Tripathy et al. PLoS One
- Soluble Cytokine Receptors (sIL-2Rα, sIL-2Rβ) Induce Subunit-Specific Behavioral Responses and Accumulate in the Cerebral Cortex and Basal Forebrain
- (2012) Steven S. Zalcman et al. PLoS One
- Differentiation and function of Foxp3+ effector regulatory T cells
- (2012) Erika Cretney et al. TRENDS IN IMMUNOLOGY
- Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice
- (2012) Flavia SA Pelegrino et al. ARTHRITIS RESEARCH & THERAPY
- Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia
- (2011) Nicolas Goardon et al. CANCER CELL
- Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division
- (2011) John T. Chang et al. IMMUNITY
- T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells
- (2011) Guoyan Cheng et al. IMMUNOLOGICAL REVIEWS
- Interleukin-2 is present in human blood vessels and released in biologically active form by heparanase
- (2011) John D Miller et al. IMMUNOLOGY AND CELL BIOLOGY
- The Basis of Distinctive IL-2– and IL-15–Dependent Signaling: Weak CD122-Dependent Signaling Favors CD8 + T Central-Memory Cell Survival but Not T Effector-Memory Cell Development
- (2011) Iris Castro et al. JOURNAL OF IMMUNOLOGY
- Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells
- (2011) Sonia Feau et al. NATURE IMMUNOLOGY
- Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
- (2011) Wei Liao et al. NATURE IMMUNOLOGY
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Continuous Activation of the CD122/STAT-5 Signaling Pathway during Selection of Antigen-Specific Regulatory T Cells in the Murine Thymus
- (2011) Jérémie D. Goldstein et al. PLoS One
- Spontaneous Autoimmune Dacryoadenitis in Aged CD25KO Mice
- (2010) Ehsan Rahimy et al. AMERICAN JOURNAL OF PATHOLOGY
- Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo
- (2010) Vandana Kalia et al. IMMUNITY
- Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells
- (2010) Matthew E. Pipkin et al. IMMUNITY
- Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity
- (2010) Thomas R. Malek et al. IMMUNITY
- PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.
- (2010) Matthias Merkenschlager et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Mechanisms of IL-2-Dependent Maintenance of Functional Regulatory T Cells
- (2010) L. Barron et al. JOURNAL OF IMMUNOLOGY
- Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms
- (2010) J. Oliaro et al. JOURNAL OF IMMUNOLOGY
- Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development
- (2010) Sergei Doulatov et al. NATURE IMMUNOLOGY
- Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
- (2009) Makoto Miyara et al. IMMUNITY
- CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses
- (2009) J. J. Obar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice
- (2009) C. S. De Paiva et al. RHEUMATOLOGY
- Regulatory mechanisms of IL-2 and IFNγ suppression by quercetin in T helper cells
- (2008) Eun Sun Yu et al. BIOCHEMICAL PHARMACOLOGY
- The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2)
- (2008) Ruth Y. Lan et al. JOURNAL OF AUTOIMMUNITY
- The Biology of Interleukin-2
- (2007) Thomas R. Malek Annual Review of Immunology
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started