Continuous requirement for the TCR in regulatory T cell function

CD83 Expression in CD4 + T Cells Modulates Inflammation and Autoimmunity

(2014) Simone Reinwald et al.   JOURNAL OF IMMUNOLOGY

Pathogen-Specific Treg Cells Expand Early during Mycobacterium tuberculosis Infection but Are Later Eliminated in Response to Interleukin-12

(2013) Shahin Shafiani et al.   IMMUNITY

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

(2013) Kate S. Smigiel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

(2013) Kevin Man et al.   NATURE IMMUNOLOGY

Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification

(2012) Robert M. Samstein et al.   CELL

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

A Broad Range of Self-Reactivity Drives Thymic Regulatory T Cell Selection to Limit Responses to Self

(2012) Hyang-Mi Lee et al.   IMMUNITY

T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development

(2012) Naganari Ohkura et al.   IMMUNITY

Cutting Edge: IL-2 Signals Determine the Degree of TCR Signaling Necessary To Support Regulatory T Cell Proliferation In Vivo

(2012) T. Zou et al.   JOURNAL OF IMMUNOLOGY

Bcl6 Controls the Th2 Inflammatory Activity of Regulatory T Cells by Repressing Gata3 Function

(2012) D. V. Sawant et al.   JOURNAL OF IMMUNOLOGY

Novel Foxo1-dependent transcriptional programs control Treg cell function

(2012) Weiming Ouyang et al.   NATURE

Foxp3+ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis

(2011) L. Tian et al.   BLOOD

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

(2010) D. B. Hoelzinger et al.   JOURNAL OF IMMUNOLOGY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity

(2010) Byron B Au-Yeung et al.   NATURE IMMUNOLOGY

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

(2009) Kylie E. Webster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking

(2009) Joong Kyu Kim et al.   PLoS One

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

(2008) Qizhi Tang et al.   IMMUNITY

Antigen-specific peripheral shaping of the natural regulatory T cell population

(2008) Stephanie K. Lathrop et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology