TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells
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Title
TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells
Authors
Keywords
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Journal
Communications Biology
Volume 5, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-04-01
DOI
10.1038/s42003-022-03214-1
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Note: Only part of the references are listed.- The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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- (2021) Giacomo Cossa et al. GENES & DEVELOPMENT
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- (2020) Giacomo Cossa et al. MOLECULAR CELL
- Using TTchem-seq for profiling nascent transcription and measuring transcript elongation
- (2020) Lea H. Gregersen et al. Nature Protocols
- CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
- (2020) Michael Tellier et al. NUCLEIC ACIDS RESEARCH
- Mechanisms of Transcription Elongation Factor DSIF (Spt4–Spt5)
- (2020) Tim-Michael Decker JOURNAL OF MOLECULAR BIOLOGY
- Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination
- (2020) Kai-Lieh Huang et al. MOLECULAR CELL
- Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II
- (2020) Pabitra K. Parua et al. Nature Communications
- Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase
- (2020) Hai Zheng et al. SCIENCE
- WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
- (2020) Helga B. Landsverk et al. Cell Reports
- Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation
- (2019) Leighton Core et al. GENES & DEVELOPMENT
- TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
- (2019) Francesca Alfei et al. NATURE
- TOX is a critical regulator of tumour-specific T cell differentiation
- (2019) Andrew C. Scott et al. NATURE
- TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
- (2019) Omar Khan et al. NATURE
- Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling
- (2019) Michael P. Meers et al. Epigenetics & Chromatin
- CUT&Tag for efficient epigenomic profiling of small samples and single cells
- (2019) Hatice S. Kaya-Okur et al. Nature Communications
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
- (2019) Daehwan Kim et al. NATURE BIOTECHNOLOGY
- 50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms
- (2019) Robert G. Roeder NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
- (2019) Wei Xu et al. IMMUNITY
- Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a “Sitting Duck Torpedo” Mechanism
- (2019) Michael A. Cortazar et al. MOLECULAR CELL
- OUP accepted manuscript
- (2018) BIOINFORMATICS
- A Cdk9–PP1 switch regulates the elongation–termination transition of RNA polymerase II
- (2018) Pabitra K. Parua et al. NATURE
- TT‐seq captures enhancer landscapes immediately after T‐cell stimulation
- (2017) Margaux Michel et al. Molecular Systems Biology
- An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
- (2017) M Ryan Corces et al. NATURE METHODS
- The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain
- (2017) Kevin M. Harlen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Functional interplay between histone H1 and HMG proteins in chromatin
- (2016) Yuri V. Postnikov et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
- (2016) Miriam Sansó et al. GENES & DEVELOPMENT
- The pol II CTD: new twists in the tail
- (2016) Justyna Zaborowska et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- The pol II CTD: new twists in the tail
- (2016) Justyna Zaborowska et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization
- (2015) Guangchuang Yu et al. BIOINFORMATICS
- Protein phosphatase 1 is a key player in nuclear events
- (2015) Sandra Rebelo et al. CELLULAR SIGNALLING
- Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination
- (2015) Liv M.I. Austenaa et al. MOLECULAR CELL
- RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II
- (2015) M. Yu et al. SCIENCE
- Tn5 transposase and tagmentation procedures for massively scaled sequencing projects
- (2014) Simone Picelli et al. GENOME RESEARCH
- Regulation of transcription factor activity by interconnected post-translational modifications
- (2014) Theresa M. Filtz et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- 4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells
- (2014) Gilad Fuchs et al. GENOME BIOLOGY
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Mechanistic Interpretation of Promoter-Proximal Peaks and RNAPII Density Maps
- (2013) Andreas H. Ehrensberger et al. CELL
- Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells
- (2013) Charles G. Danko et al. MOLECULAR CELL
- Software for Computing and Annotating Genomic Ranges
- (2013) Michael Lawrence et al. PLoS Computational Biology
- PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth
- (2013) Anita Ciurciu et al. PLoS Genetics
- Promoter clearance by RNA polymerase II
- (2012) Donal S. Luse Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Fcp1 Dephosphorylation of the RNA Polymerase II C-Terminal Domain Is Required for Efficient Transcription of Heat Shock Genes
- (2012) N. J. Fuda et al. MOLECULAR AND CELLULAR BIOLOGY
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
- (2012) Karen Adelman et al. NATURE REVIEWS GENETICS
- clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
- (2012) Guangchuang Yu et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Selective Depletion of rRNA Enables Whole Transcriptome Profiling of Archival Fixed Tissue
- (2012) John D. Morlan et al. PLoS One
- Gene Loops Enhance Transcriptional Directionality
- (2012) S. M. Tan-Wong et al. SCIENCE
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- c-Myc Regulates Transcriptional Pause Release
- (2010) Peter B. Rahl et al. CELL
- Identification and Characterization of a Novel Human PP1 Phosphatase Complex
- (2010) Jeong-Heon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A clustering approach for identification of enriched domains from histone modification ChIP-Seq data
- (2009) Chongzhi Zang et al. BIOINFORMATICS
- rtracklayer: an R package for interfacing with genome browsers
- (2009) M. Lawrence et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Serine/Threonine Phosphatases: Mechanism through Structure
- (2009) Yigong Shi CELL
- Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis
- (2009) Ming Yu et al. MOLECULAR CELL
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