50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms

The role of transcription in shaping the spatial organization of the genome

(2019) Bas van Steensel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway

(2019) Miho Shimada et al.   MOLECULAR CELL

Signaling to and from the RNA Polymerase III Transcription and Processing Machinery

(2018) Ian M. Willis et al.   Annual Review of Biochemistry

Emerging Roles of Non-Coding RNA Transcription

(2018) Minna U. Kaikkonen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural basis of RNA polymerase III transcription initiation

(2018) Guillermo Abascal-Palacios et al.   NATURE

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1

(2018) Miki Jishage et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phase Separation, Protein Disorder, and Enhancer Function

(2018) Steven Hahn   CELL

The Human Transcription Factors

(2018) Samuel A. Lambert et al.   CELL

The many lives of KATs — detectors, integrators and modulators of the cellular environment

(2018) Bilal N. Sheikh et al.   NATURE REVIEWS GENETICS

Organizational principles of 3D genome architecture

(2018) M. Jordan Rowley et al.   NATURE REVIEWS GENETICS

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

(2018) Avinash B. Patel et al.   SCIENCE

A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription

(2017) Shu-Ping Wang et al.   MOLECULAR CELL

Core Mediator structure at 3.4 Å extends model of transcription initiation complex

(2017) Kayo Nozawa et al.   NATURE

Mediator structure and rearrangements required for holoenzyme formation

(2017) Kuang-Lei Tsai et al.   NATURE

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

(2016) Philip J. Robinson et al.   CELL

Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis

(2016) Zhengjian Zhang et al.   GENES & DEVELOPMENT

Mediator: A Drawbridge across the Enhancer-Promoter Divide

(2016) Sohail Malik et al.   MOLECULAR CELL

Near-atomic resolution visualization of human transcription promoter opening

(2016) Yuan He et al.   NATURE

Transcription initiation complex structures elucidate DNA opening

(2016) C. Plaschka et al.   NATURE

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

(2016) Robert K. Louder et al.   NATURE

Structure of the initiation-competent RNA polymerase I and its implication for transcription

(2016) Michael Pilsl et al.   Nature Communications

Enhancers, enhancers – from their discovery to today’s universe of transcription enhancers

(2015) Walter Schaffner   BIOLOGICAL CHEMISTRY

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

(2015) Benjamin R. Sabari et al.   MOLECULAR CELL

Architecture of the RNA polymerase II–Mediator core initiation complex

(2015) C. Plaschka et al.   NATURE

The Mediator complex: a central integrator of transcription

(2015) Benjamin L. Allen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of an RNA polymerase II preinitiation complex

(2015) Kenji Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

(2014) Kuang-Lei Tsai et al.   CELL

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit

(2014) Murat A Cevher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53

(2013) Zhanyun Tang et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

(2013) Shannon M. Lauberth et al.   CELL

A TAF4 coactivator function for E proteins that involves enhanced TFIID binding

(2013) W.-Y. Chen et al.   GENES & DEVELOPMENT

Structural visualization of key steps in human transcription initiation

(2013) Yuan He et al.   NATURE

Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries

(2012) Alessandro Vannini et al.   MOLECULAR CELL

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

Mediator-dependent nuclear receptor function

(2011) Wei Chen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Perspectives on the RNA polymerase II core promoter

(2011) James T. Kadonaga   Wiley Interdisciplinary Reviews-Developmental Biology

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS

(2010) Jaehoon Kim et al.   CELL

Highly Compacted Chromatin Formed In Vitro Reflects the Dynamics of Transcription Activation In Vivo

(2010) Guohong Li et al.   MOLECULAR CELL

Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation

(2010) James A. Goodrich et al.   NATURE REVIEWS GENETICS

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

(2010) Sohail Malik et al.   NATURE REVIEWS GENETICS

The basal initiation machinery: beyond the general transcription factors

(2009) Timothy W. Sikorski et al.   CURRENT OPINION IN CELL BIOLOGY

Structure of Eukaryotic RNA Polymerases

(2008) P. Cramer et al.   Annual Review of Biophysics