Evolution of Bacterial Persistence to Antibiotics during a 50,000-Generation Experiment in an Antibiotic-Free Environment

Ecology and evolution of antibiotic persistence

(2021) L. Verstraete et al.   TRENDS IN MICROBIOLOGY

The Surprising Creativity of Digital Evolution: A Collection of Anecdotes from the Evolutionary Computation and Artificial Life Research Communities

(2020) Joel Lehman et al.   ARTIFICIAL LIFE

Evolutionary causes and consequences of bacterial antibiotic persistence

(2020) Erik Bakkeren et al.   NATURE REVIEWS MICROBIOLOGY

Noise and Synthetic Biology: How to Deal with Stochasticity?

(2020) Miguel Prado Casanova   NanoEthics

Phenotypic noise and the cost of complexity

(2020) Charles Rocabert et al.   EVOLUTION

Tolerant/Persister Cancer Cells and the Path to Resistance to Targeted Therapy

(2020) Mirna Swayden et al.   Cells

Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates

(2019) Etthel Martha Windels et al.   ISME Journal

Changes in Intrinsic Antibiotic Susceptibility during a Long-Term Evolution Experiment with Escherichia coli

(2019) Otmane Lamrabet et al.   mBio

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Bacterial Persisters and Infection: Past, Present, and Progressing

(2019) Bridget Gollan et al.   Annual Review of Microbiology

Bacterial persistence: Fundamentals and clinical importance

(2019) Sung-Hee Jung et al.   JOURNAL OF MICROBIOLOGY

The mean and noise of stochastic gene transcription with cell division

(2018) Qi Wang et al.   Mathematical Biosciences and Engineering

Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy

(2018) Roderich Roemhild et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters

(2018) Clément Vulin et al.   Nature Communications

Dormant, quiescent, tolerant and persister cells: Four synonyms for the same target in cancer

(2018) François M. Vallette et al.   BIOCHEMICAL PHARMACOLOGY

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

(2018) Alessandro Cassini et al.   LANCET INFECTIOUS DISEASES

Adaptive Prediction Emerges Over Short Evolutionary Time Scales

(2017) Adrián López García de Lomana et al.   Genome Biology and Evolution

Genetic Basis of Exploiting Ecological Opportunity During the Long-Term Diversification of a Bacterial Population

(2017) Jessika Consuegra et al.   JOURNAL OF MOLECULAR EVOLUTION

The dynamics of molecular evolution over 60,000 generations

(2017) Benjamin H. Good et al.   NATURE

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Metabolic modelling in a dynamic evolutionary framework predicts adaptive diversification of bacteria in a long-term evolution experiment

(2016) Tobias Großkopf et al.   BMC EVOLUTIONARY BIOLOGY

Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging

(2016) Daniel Nichol et al.   GENETICS

Persistence and resistance as complementary bacterial adaptations to antibiotics

(2016) T. Vogwill et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells

(2016) Yingying Pu et al.   MOLECULAR CELL

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Global tRNA misacylation induced by anaerobiosis and antibiotic exposure broadly increases stress resistance inEscherichia coli

(2016) Michael H. Schwartz et al.   NUCLEIC ACIDS RESEARCH

Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?

(2016) Marlieke E. A. de Kraker et al.   PLOS MEDICINE

Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging

(2016) Daniel Nichol et al.   GENETICS

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

(2016) Bram Van den Bergh et al.   Nature Microbiology

Comparing denominator degrees of freedom approximations for the generalized linear mixed model in analyzing binary outcome in small sample cluster-randomized trials

(2015) Peng Li et al.   BMC Medical Research Methodology

Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences

(2015) Günter Vogt   JOURNAL OF BIOSCIENCES

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

Fitness trade-offs explain low levels of persister cells in the opportunistic pathogenPseudomonas aeruginosa

(2015) Kristine Stepanyan et al.   MOLECULAR ECOLOGY

Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

(2014) Lee W. Goneau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Persistence: a copacetic and parsimonious hypothesis for the existence of non-inherited resistance to antibiotics

(2014) Bruce R Levin et al.   CURRENT OPINION IN MICROBIOLOGY

Epistasis and Allele Specificity in the Emergence of a Stable Polymorphism in Escherichia coli

(2014) J. Plucain et al.   SCIENCE

The importance of the viable but non-culturable state in human bacterial pathogens

(2014) Laam Li et al.   Frontiers in Microbiology

Quantitative analysis of persister fractions suggests different mechanisms of formation among environmental isolates of E. coli

(2013) Niels Hofsteenge et al.   BMC MICROBIOLOGY

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Phenotypic Effects of Salt and Heat Stress over Three Generations in Arabidopsis thaliana

(2013) Léonie Suter et al.   PLoS One

Long-Term Dynamics of Adaptation in Asexual Populations

(2013) M. J. Wiser et al.   SCIENCE

A method for high throughput determination of viable bacteria cell counts in 96-well plates

(2012) Ronen Hazan et al.   BMC MICROBIOLOGY

Large mutational target size for rapid emergence of bacterial persistence

(2012) H. S. Girgis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GENETIC VARIATION FOR ANTIBIOTIC PERSISTENCE IN ESCHERICHIA COLI

(2011) Balint Stewart et al.   EVOLUTION

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Understanding Latent Tuberculosis: A Moving Target

(2010) P. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of Candida albicans

(2009) M. D. LaFleur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genome Sequences of Escherichia coli B strains REL606 and BL21(DE3)

(2009) Haeyoung Jeong et al.   JOURNAL OF MOLECULAR BIOLOGY

Adaptive prediction of environmental changes by microorganisms

(2009) Amir Mitchell et al.   NATURE

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Death and cannibalism in a seasonal environment facilitate bacterial coexistence

(2008) Daniel E. Rozen et al.   ECOLOGY LETTERS

Relevance of phenotypic noise to adaptation and evolution

(2008) K. Kaneko et al.   IET Systems Biology