Phenotypic noise and the cost of complexity

Dimensional Reduction in Evolving Spin-Glass Model: Correlation of Phenotypic Responses to Environmental and Mutational Changes

(2020) Ayaka Sakata et al.   PHYSICAL REVIEW LETTERS

Challenges in measuring and understanding biological noise

(2019) Nils Eling et al.   NATURE REVIEWS GENETICS

Phenotypic variability can promote the evolution of adaptive plasticity by reducing the stringency of natural selection

(2019) Jeremy Draghi   JOURNAL OF EVOLUTIONARY BIOLOGY

The Evolution of Variance Control

(2019) Marjolein Bruijning et al.   TRENDS IN ECOLOGY & EVOLUTION

Phenotypic plasticity, global change, and the speed of adaptive evolution

(2019) Patricia Gibert et al.   Current Opinion in Insect Science

Characterization of noise in multistable genetic circuits reveals ways to modulate heterogeneity

(2018) Sayuri Katharina Hortsch et al.   PLoS One

Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest

(2018) José Reyes et al.   MOLECULAR CELL

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

(2018) Fabien Duveau et al.   eLife

The causes of evolvability and their evolution

(2018) Joshua L. Payne et al.   NATURE REVIEWS GENETICS

The evolution of phenotypic integration: How directional selection reshapes covariation in mice

(2017) Anna Penna et al.   EVOLUTION

Heritable Micro-environmental Variance Covaries with Fitness in an Outbred Population ofDrosophila serrata

(2017) Jacqueline L. Sztepanacz et al.   GENETICS

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

(2017) Sydney M. Shaffer et al.   NATURE

Phenotypic heterogeneity promotes adaptive evolution

(2017) Zoltán Bódi et al.   PLOS BIOLOGY

Heritable Micro-environmental Variance Covaries with Fitness in an Outbred Population ofDrosophila serrata

(2017) Jacqueline L. Sztepanacz et al.   GENETICS

Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness

(2016) Leeat Keren et al.   CELL

Genetic variation in variability: Phenotypic variability of fledging weight and its evolution in a songbird population

(2016) Han A. Mulder et al.   EVOLUTION

Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process

(2016) Angélique Richard et al.   PLOS BIOLOGY

The developmental genetics of biological robustness

(2015) Lamia Mestek Boukhibar et al.   ANNALS OF BOTANY

Genetic evolution, plasticity, and bet-hedging as adaptive responses to temporally autocorrelated fluctuating selection: A quantitative genetic model

(2015) Jarle Tufto   EVOLUTION

Population genetics of non-genetic traits: Evolutionary roles of stochasticity in gene expression

(2015) Katsuhiko Mineta et al.   GENE

Single-cell phenomics in budding yeast

(2015) Yoshikazu Ohya et al.   MOLECULAR BIOLOGY OF THE CELL

Selection on noise constrains variation in a eukaryotic promoter

(2015) Brian P. H. Metzger et al.   NATURE

The alignment between phenotypic plasticity, the major axis of genetic variation and the response to selection

(2015) Martin I. Lind et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Utility of Fisher's Geometric Model in Evolutionary Genetics

(2014) O. Tenaillon   Annual Review of Ecology Evolution and Systematics

Fisher’s Geometrical Model Emerges as a Property of Complex Integrated Phenotypic Networks

(2014) Guillaume Martin   GENETICS

Rethinking phenotypic plasticity and its consequences for individuals, populations and species

(2014) A Forsman   HEREDITY

Regulated Noise in the Epigenetic Landscape of Development and Disease

(2012) Elisabet Pujadas et al.   CELL

PHENOTYPIC PLASTICITY FACILITATES MUTATIONAL VARIANCE, GENETIC VARIANCE, AND EVOLVABILITY ALONG THE MAJOR AXIS OF ENVIRONMENTAL VARIATION

(2012) Jeremy A. Draghi et al.   EVOLUTION

Cellular Noise Regulons Underlie Fluctuations in Saccharomyces cerevisiae

(2012) Jacob Stewart-Ornstein et al.   MOLECULAR CELL

Towards experimental manipulation of stochasticity in gene expression

(2012) José Viñuelas et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Tumor progression: Chance and necessity in Darwinian and Lamarckian somatic (mutationless) evolution

(2012) Sui Huang   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer

(2012) Steven A. Frank et al.   PLOS BIOLOGY

Inheritance Beyond Plain Heritability: Variance-Controlling Genes in Arabidopsis thaliana

(2012) Xia Shen et al.   PLoS Genetics

Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits

(2011) Carlos Espinosa-Soto et al.   BMC EVOLUTIONARY BIOLOGY

Genetic analysis of environmental variation

(2011) WILLIAM G. HILL et al.   Genetics Research

Impact of gene expression noise on organismal fitness and the efficacy of natural selection

(2011) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EVOLUTION OF VARIATION AND VARIABILITY UNDER FLUCTUATING, STABILIZING, AND DISRUPTIVE SELECTION

(2010) Christophe Pélabon et al.   EVOLUTION

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Experimental evolution of bet hedging

(2009) Hubertus J. E. Beaumont et al.   NATURE

Genetic variation and quantitative trait loci associated with developmental stability and the environmental correlation between traits in maize

(2008) BERNARDO ORDAS et al.   Genetics Research

Pleiotropic scaling of gene effects and the ‘cost of complexity’

(2008) Günter P. Wagner et al.   NATURE

Evolution of Evolvability in Gene Regulatory Networks

(2008) Anton Crombach et al.   PLoS Computational Biology