Evolutionary causes and consequences of bacterial antibiotic persistence

Proteomic Investigation of Tolerant Escherichia coli Populations from Cyclic Antibiotic Treatment

(2020) Jordy Evan Sulaiman et al.   JOURNAL OF PROTEOME RESEARCH

Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation

(2020) Anupama Khare et al.   mSystems

Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates

(2019) Etthel Martha Windels et al.   ISME Journal

Evolutionary highways to persistent bacterial infection

(2019) Jennifer A. Bartell et al.   Nature Communications

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract

(2019) Markus Furter et al.   Cell Reports

Slow growth determines nonheritable antibiotic resistance in Salmonella enterica

(2019) Mauricio H. Pontes et al.   Science Signaling

Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung

(2019) Adrian Kordes et al.   Nature Communications

Bacterial Persisters and Infection: Past, Present, and Progressing

(2019) Bridget Gollan et al.   Annual Review of Microbiology

Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut

(2019) Erik Bakkeren et al.   NATURE

The evolution of antibiotic resistance

(2019) R. Craig MacLean et al.   SCIENCE

Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance

(2019) Liselot Dewachter et al.   MOLECULAR CELL

Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation

(2019) Olivier Cunrath et al.   SCIENCE

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

(2019) Sandra Y. Wotzka et al.   Nature Microbiology

Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection

(2019) Trung H.M. Pham et al.   Cell Host & Microbe

Tasked with a Challenging Objective: Why Do Neutrophils Fail to Battle Pseudomonas aeruginosa Biofilms

(2019) Jennifer Geddes-McAlister et al.   Pathogens

Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics

(2018) Valerie Defraine et al.   DRUG RESISTANCE UPDATES

Targeting the Latent Reservoir for HIV-1

(2018) Srona Sengupta et al.   IMMUNITY

Pseudomonas aeruginosatranscriptome during human infection

(2018) Daniel M. Cornforth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage Sb-1 enhances antibiotic activity against biofilm, degrades exopolysaccharide matrix and targets persisters of Staphylococcus aureus

(2018) Tamta Tkhilaishvili et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Duration of travel-associated faecal colonisation with ESBL-producing Enterobacteriaceae - A one year follow-up study

(2018) Åse ÖstholmBalkhed et al.   PLoS One

Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters

(2018) Clément Vulin et al.   Nature Communications

Evolutionary epidemiology models to predict the dynamics of antibiotic resistance

(2018) François Blanquart   Evolutionary Applications

Salmonella persisters undermine host immune defenses during antibiotic treatment

(2018) Daphne A. C. Stapels et al.   SCIENCE

Fungal persister cells: The basis for recalcitrant infections?

(2018) Jurgen Wuyts et al.   PLoS Pathogens

Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics

(2017) Arnaud Gutierrez et al.   MOLECULAR CELL

Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity

(2017) E. Hesper Rego et al.   NATURE

High-avidity IgA protects the intestine by enchaining growing bacteria

(2017) Kathrin Moor et al.   NATURE

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Inflammation boosts bacteriophage transfer between Salmonella spp.

(2017) Médéric Diard et al.   SCIENCE

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

TDtest: easy detection of bacterial tolerance and persistence in clinical isolates by a modified disk-diffusion assay

(2017) Orit Gefen et al.   Scientific Reports

In VitroEmergence of High Persistence upon Periodic Aminoglycoside Challenge in the ESKAPE Pathogens

(2016) Joran Elie Michiels et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Persistent Infections by NontyphoidalSalmonellain Humans: Epidemiology and Genetics

(2016) Alex Marzel et al.   CLINICAL INFECTIOUS DISEASES

Molecular mechanisms and clinical implications of bacterial persistence

(2016) Joran Elie Michiels et al.   DRUG RESISTANCE UPDATES

Persistence and resistance as complementary bacterial adaptations to antibiotics

(2016) T. Vogwill et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Immune activation of the host cell induces drug tolerance inMycobacterium tuberculosisboth in vitro and in vivo

(2016) Yancheng Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Peracetic Acid Treatment Generates Potent Inactivated Oral Vaccines from a Broad Range of Culturable Bacterial Species

(2016) Kathrin Moor et al.   Frontiers in Immunology

Antimicrobial resistance: Survival by reversible resistance

(2016) Wolf-Dietrich Hardt   Nature Microbiology

Antibiotic failure mediated by a resistant subpopulation in Enterobacter cloacae

(2016) Victor I. Band et al.   Nature Microbiology

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

(2016) Bram Van den Bergh et al.   Nature Microbiology

Heteroresistance to Colistin in Klebsiella pneumoniae Associated with Alterations in the PhoPQ Regulatory System

(2015) Aurélie Jayol et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Novel Point Mutation Promotes Growth Phase-Dependent Daptomycin Tolerance in Staphylococcus aureus

(2015) Lukas Mechler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

(2015) Roi Avraham et al.   CELL

Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms

(2015) Giulia Manina et al.   Cell Host & Microbe

Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections

(2015) John A. Crump et al.   CLINICAL MICROBIOLOGY REVIEWS

Treatment of Tuberculosis

(2015) C. Robert Horsburgh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

(2015) Stefany Moreno-Gamez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of stationary phase respiration impairs persister formation in E. coli

(2015) Mehmet A. Orman et al.   Nature Communications

Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

(2014) Lee W. Goneau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coliin Swiss Travellers to South Asia– a prospective observational multicentre cohort study looking at epidemiology, microbiology and risk factors

(2014) Esther Kuenzli et al.   BMC INFECTIOUS DISEASES

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa

(2014) Mikael E. Sellin et al.   Cell Host & Microbe

Antibiotic Treatment Selects for Cooperative Virulence of Salmonella Typhimurium

(2014) Médéric Diard et al.   CURRENT BIOLOGY

Persistence: a copacetic and parsimonious hypothesis for the existence of non-inherited resistance to antibiotics

(2014) Bruce R Levin et al.   CURRENT OPINION IN MICROBIOLOGY

Phenotypic bistability in Escherichia coli's central carbon metabolism

(2014) O. Kotte et al.   Molecular Systems Biology

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Direct measurement of oxidative and nitrosative stress dynamics inSalmonellainside macrophages

(2014) Joris van der Heijden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

(2014) Patrick Kaiser et al.   PLOS BIOLOGY

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

(2014) Markus Arnoldini et al.   PLOS BIOLOGY

Inflammation Fuels Colicin Ib-Dependent Competition of Salmonella Serovar Typhimurium and E. coli in Enterobacterial Blooms

(2014) Lubov Petkova Nedialkova et al.   PLoS Pathogens

Staphylococcus aureus Osteomyelitis: Bad to the Bone

(2013) Michael E. Olson et al.   Cell Host & Microbe

Microbial Persistence and the Road to Drug Resistance

(2013) Nadia R. Cohen et al.   Cell Host & Microbe

Activated ClpP kills persisters and eradicates a chronic biofilm infection

(2013) B. P. Conlon et al.   NATURE

Stabilization of cooperative virulence by the expression of an avirulent phenotype

(2013) Médéric Diard et al.   NATURE

'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution

(2013) Bärbel Stecher et al.   NATURE REVIEWS MICROBIOLOGY

NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium

(2013) Boas Felmy et al.   PLoS One

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response

(2013) Sarah Schmidt Grant et al.   Virulence

Importance of prophages to evolution and virulence of bacterial pathogens

(2013) Louis-Charles Fortier et al.   Virulence

Salmonella Uses Energy Taxis to Benefit from Intestinal Inflammation

(2013) Fabian Rivera-Chávez et al.   PLoS Pathogens

Role of Oxidative Stress in Persister Tolerance

(2012) Yanxia Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The interconnection between biofilm formation and horizontal gene transfer

(2012) Jonas Stenløkke Madsen et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

A Stress-Inducible Quorum-Sensing Peptide Mediates the Formation of Persister Cells with Noninherited Multidrug Tolerance

(2012) V. Leung et al.   JOURNAL OF BACTERIOLOGY

Signaling-mediated bacterial persister formation

(2012) Nicole M Vega et al.   Nature Chemical Biology

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae

(2012) B. Stecher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shedding light on Salmonella carriers

(2012) Smita Gopinath et al.   TRENDS IN MICROBIOLOGY

Bacterial persistence increases as environmental fitness decreases

(2012) Seok Hoon Hong et al.   Microbial Biotechnology

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

Dissemination of Persistent Intestinal Bacteria via the Mesenteric Lymph Nodes Causes Typhoid Relapse

(2011) Amanda J. Griffin et al.   INFECTION AND IMMUNITY

Comparison of Asymptomatic Bacteriuria Escherichia coli Isolates from Healthy Individuals versus Those from Hospital Patients Shows that Long-Term Bladder Colonization Selects for Attenuated Virulence Phenotypes

(2011) Ellaine Salvador et al.   INFECTION AND IMMUNITY

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

(2011) Kyle R. Allison et al.   NATURE

Microbial seed banks: the ecological and evolutionary implications of dormancy

(2011) Jay T. Lennon et al.   NATURE REVIEWS MICROBIOLOGY

Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota

(2011) P. Thiennimitr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria

(2011) D. Nguyen et al.   SCIENCE

Salmonella bongori Provides Insights into the Evolution of the Salmonellae

(2011) Maria Fookes et al.   PLoS Pathogens

The Cost of Virulence: Retarded Growth of Salmonella Typhimurium Cells Expressing Type III Secretion System 1

(2011) Alexander Sturm et al.   PLoS Pathogens

Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs againstMycobacterium tuberculosis

(2010) Mary A. De Groote et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Delineation of a Bacterial Starvation Stress Response Network Which Can Mediate Antibiotic Tolerance Development

(2010) D. K. C. Fung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Viral Latency and Its Regulation: Lessons from the γ-Herpesviruses

(2010) Samuel H. Speck et al.   Cell Host & Microbe

Pseudomonas aeruginosa Increases Formation of Multidrug-Tolerant Persister Cells in Response to Quorum-Sensing Signaling Molecules

(2010) N. Moker et al.   JOURNAL OF BACTERIOLOGY

Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis

(2010) L. R. Mulcahy et al.   JOURNAL OF BACTERIOLOGY

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

The population genetics of commensal Escherichia coli

(2010) Olivier Tenaillon et al.   NATURE REVIEWS MICROBIOLOGY

Chronic and acute infection of the gall bladder by Salmonella Typhi: understanding the carrier state

(2010) Geoffrey Gonzalez-Escobedo et al.   NATURE REVIEWS MICROBIOLOGY

Dynamics of intracellular bacterial replication at the single cell level

(2010) Sophie Helaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

(2010) Kathrin Endt et al.   PLoS Pathogens

Lipocalin-2 Resistance Confers an Advantage to Salmonella enterica Serotype Typhimurium for Growth and Survival in the Inflamed Intestine

(2009) Manuela Raffatellu et al.   Cell Host & Microbe

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

(2009) Ronald S. Flannagan et al.   NATURE REVIEWS MICROBIOLOGY

Bacterial competition: surviving and thriving in the microbial jungle

(2009) Michael E. Hibbing et al.   NATURE REVIEWS MICROBIOLOGY

Phagocytic Superoxide Specifically Damages an Extracytoplasmic Target to Inhibit or Kill Salmonella

(2009) Maureen Craig et al.   PLoS One

Staphylococcus aureus as an intracellular pathogen: the role of small colony variants

(2009) Parham Sendi et al.   TRENDS IN MICROBIOLOGY

Self-destructive cooperation mediated by phenotypic noise

(2008) Martin Ackermann et al.   NATURE

Nongenetic Individuality in the Host–Phage Interaction

(2008) Sivan Pearl et al.   PLOS BIOLOGY

Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airway

(2007) Sophie Moreau-Marquis et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS