Definitions and guidelines for research on antibiotic persistence

The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification

(2019) Hervé Nicoloff et al.   Nature Microbiology

Targeting Antibiotic Tolerance, Pathogen by Pathogen

(2018) Sylvain Meylan et al.   CELL

Mechanisms of M. tuberculosis Immune Evasion as Challenges to TB Vaccine Design

(2018) Joel D. Ernst   Cell Host & Microbe

Multidrug efflux pumps: structure, function and regulation

(2018) Dijun Du et al.   NATURE REVIEWS MICROBIOLOGY

Timing of DNA damage responses impacts persistence to fluoroquinolones

(2018) Wendy W. K. Mok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia

(2018) Alexander Rosenberg et al.   Nature Communications

Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters

(2018) Clément Vulin et al.   Nature Communications

Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics

(2017) Arnaud Gutierrez et al.   MOLECULAR CELL

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

Molecular mechanisms and clinical implications of bacterial persistence

(2016) Joran Elie Michiels et al.   DRUG RESISTANCE UPDATES

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

(2016) Bram Van den Bergh et al.   Nature Microbiology

Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms

(2015) Giulia Manina et al.   Cell Host & Microbe

Antimicrobial Heteroresistance: an Emerging Field in Need of Clarity

(2015) Omar M. El-Halfawy et al.   CLINICAL MICROBIOLOGY REVIEWS

A functional perspective on phenotypic heterogeneity in microorganisms

(2015) Martin Ackermann   NATURE REVIEWS MICROBIOLOGY

Classic reaction kinetics can explain complex patterns of antibiotic action

(2015) Pia Abel zur Wiesch et al.   Science Translational Medicine

Single-Cell Tracking Reveals Antibiotic-Induced Changes in Mycobacterial Energy Metabolism

(2015) Željka Maglica et al.   mBio

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

Persistence: a copacetic and parsimonious hypothesis for the existence of non-inherited resistance to antibiotics

(2014) Bruce R Levin et al.   CURRENT OPINION IN MICROBIOLOGY

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

(2014) Patrick Kaiser et al.   PLOS BIOLOGY

Induction of the Cpx Envelope Stress Pathway Contributes to Escherichia coli Tolerance to Antimicrobial Peptides

(2013) Bianca Audrain et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolic Control of Persister Formation in Escherichia coli

(2013) Stephanie M. Amato et al.   MOLECULAR CELL

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Pharmacodynamics, Population Dynamics, and the Evolution of Persistence in Staphylococcus aureus

(2013) Paul J. T. Johnson et al.   PLoS Genetics

Signaling-mediated bacterial persister formation

(2012) Nicole M Vega et al.   Nature Chemical Biology

Age of Inoculum Strongly Influences Persister Frequency and Can Mask Effects of Mutations Implicated in Altered Persistence

(2011) H. Luidalepp et al.   JOURNAL OF BACTERIOLOGY

Persistence of Uropathogenic Escherichia coli in the Face of Multiple Antibiotics

(2010) M. G. Blango et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Dynamics of Antibiotic Treatment: a Mathematical Model and Hypotheses for Time-Kill and Continuous-Culture Experiments

(2010) B. R. Levin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Frequency of Persisters in Escherichia coli Reflects the Kinetics of Awakening from Dormancy

(2010) A. Joers et al.   JOURNAL OF BACTERIOLOGY

Automated imaging with ScanLag reveals previously undetectable bacterial growth phenotypes

(2010) Irit Levin-Reisman et al.   NATURE METHODS

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

(2010) Eitan Rotem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

(2010) Tobias Dörr et al.   PLOS BIOLOGY

Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of Candida albicans

(2009) M. D. LaFleur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AmpC  -Lactamases

(2009) G. A. Jacoby   CLINICAL MICROBIOLOGY REVIEWS