Recent Progress of Exosome Isolation and Peptide Recognition-Guided Strategies for Exosome Research

Molecular Identification of Tumor-Derived Extracellular Vesicles Using Thermophoresis-Mediated DNA Computation

(2021) Yike Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exosome detection via the ultrafast-isolation system: EXODUS

(2021) Yuchao Chen et al.   NATURE METHODS

Magnetic Colloid Antibodies Accelerate Small Extracellular Vesicles Isolation for Point-of-Care Diagnostics

(2021) Jingjing Yang et al.   NANO LETTERS

Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery

(2021) Tin Chanh Pham et al.   Journal of Extracellular Vesicles

Anti-Tim4 Grafting Strongly Hydrophilic Metal–Organic Frameworks Immunoaffinity Flake for High-Efficiency Capture and Separation of Exosomes

(2021) Lei Zhang et al.   ANALYTICAL CHEMISTRY

Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer

(2021) Fei Tian et al.   Nature Communications

Co-Isolation of Cytokines and Exosomes: Implications for Immunomodulation Studies

(2021) Shawna Benjamin-Davalos et al.   Frontiers in Immunology

Exosome-Mediated Delivery of the Neuroprotective Peptide PACAP38 Promotes Retinal Ganglion Cell Survival and Axon Regeneration in Rats With Traumatic Optic Neuropathy

(2021) Tian Wang et al.   Frontiers in Cell and Developmental Biology

Rapid Capture of Cancer Extracellular Vesicles by Lipid Patch Microarrays

(2021) Hui‐Yu Liu et al.   ADVANCED MATERIALS

High-Throughput Single-Cell Extracellular Vesicle Secretion Analysis on a Desktop Scanner without Cell Counting

(2021) Fengjiao Zhu et al.   ANALYTICAL CHEMISTRY

Coupling Aptamer‐based Protein Tagging with Metabolic Glycan Labeling for In Situ Visualization and Biological Function Study of Exosomal Protein‐Specific Glycosylation

(2021) Lin Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor-associated exosomes promote lung cancer metastasis through multiple mechanisms

(2021) Chunyang Jiang et al.   Molecular Cancer

The power of imaging to understand extracellular vesicle biology in vivo

(2021) Frederik J. Verweij et al.   NATURE METHODS

Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma

(2021) Bo Ning et al.   Nature Nanotechnology

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

(2021) Guillermo Bordanaba-Florit et al.   Nature Protocols

Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9

(2021) Mathilde Mathieu et al.   Nature Communications

Advanced Nanotechnologies for Extracellular Vesicle‐Based Liquid Biopsy

(2021) Li Min et al.   Advanced Science

An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma

(2021) Jongmin Park et al.   Nature Biomedical Engineering

Establishment of a simplified dichotomic size‐exclusion chromatography for isolating extracellular vesicles toward clinical applications

(2021) Jiahui Guo et al.   Journal of Extracellular Vesicles

LncRNA‐encoded microproteins: A new form of cargo in cell culture‐derived and circulating extracellular vesicles

(2021) Tanxi Cai et al.   Journal of Extracellular Vesicles

Label-Free Isolation of Exosomes Using Microfluidic Technologies

(2021) Sara Hassanpour Tamrin et al.   ACS Nano

Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID‐19 Therapy

(2021) Feng Xie et al.   ADVANCED MATERIALS

Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy

(2021) Qian‐Fang Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ExoSD chips for high-purity immunomagnetic separation and high-sensitivity detection of gastric cancer cell-derived exosomes

(2021) Zixian Yu et al.   BIOSENSORS & BIOELECTRONICS

Magnetic particle based liquid biopsy chip for isolation of extracellular vesicles and characterization by gene amplification

(2021) Srinivas Bathini et al.   BIOSENSORS & BIOELECTRONICS

Promotion or inhibition of extracellular vesicle release: Emerging therapeutic opportunities

(2021) Yujia Hao et al.   JOURNAL OF CONTROLLED RELEASE

The genetic source tracking of human urinary exosomes

(2021) Qingfu Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

(2021) Enja Schneider et al.   Nature Communications

Coordination of fungal biofilm development by extracellular vesicle cargo

(2021) Robert Zarnowski et al.   Nature Communications

Small Intestinal Submucosa Membrane Modified by Fusion Peptide‐Mediated Extracellular Vesicles to Promote Tissue Regeneration

(2021) Lei Zhang et al.   Advanced Healthcare Materials

Roles of extracellular vesicles in the aging microenvironment and age‐related diseases

(2021) Yujia Yin et al.   Journal of Extracellular Vesicles

An Electrochemical Biosensor Designed by Using Zr-Based Metal–Organic Frameworks for the Detection of Glioblastoma-Derived Exosomes with Practical Application

(2020) Zhaowei Sun et al.   ANALYTICAL CHEMISTRY

Acoustic Immunosensing of Exosomes Using a Quartz Crystal Microbalance with Dissipation Monitoring

(2020) Jugal Suthar et al.   ANALYTICAL CHEMISTRY

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Exosomal PD-L1 functions as an immunosuppressant to promote wound healing

(2020) Dandan Su et al.   Journal of Extracellular Vesicles

Evaluation of exosome separation from human serum by frit-inlet asymmetrical flow field-flow fractionation and multiangle light scattering

(2020) Young Beom Kim et al.   ANALYTICA CHIMICA ACTA

Tumor‐exocytosed exosome/AIEgen hybrid nano‐vesicles facilitate efficient tumor penetration and photodynamic therapy

(2020) Daoming Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody-Conjugated Signaling Nanocavities Fabricated by Dynamic Molding for Detecting Cancers Using Small Extracellular Vesicle Markers from Tears

(2020) Toshifumi Takeuchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice

(2020) Bingfeng Zuo et al.   Nature Communications

Deconstruction of Heterogeneity of Size-Dependent Exosome Subpopulations from Human Urine by Profiling N-Glycoproteomics and Phosphoproteomics Simultaneously

(2020) Haoyang Zheng et al.   ANALYTICAL CHEMISTRY

Exosome Purification and Analysis Using a Facile Microfluidic Hydrodynamic Trapping Device

(2020) Mahnoush Tayebi et al.   ANALYTICAL CHEMISTRY

Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells

(2020) Megan K. Ruhland et al.   CANCER CELL

Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma‐Derived Extracellular Vesicles for Downstream Functional Studies

(2020) Jiantong Dong et al.   ADVANCED FUNCTIONAL MATERIALS

Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

(2020) Na Sun et al.   Nature Communications

Tracing Tumor‐derived Exosomal PD‐L1 by Dual‐aptamer Activated Proximity‐induced Droplet Digital PCR

(2020) Bingqian Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-step quantification of salivary exosomes based on combined aptamer recognition and quantum dot signal amplification

(2020) Min Wu et al.   BIOSENSORS & BIOELECTRONICS

Ultrasensitive electrochemiluminescence biosensor for the detection of tumor exosomes based on peptide recognition and luminol-AuNPs@g-C3N4 nanoprobe signal amplification

(2020) Xuejiao Liu et al.   TALANTA

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

(2019) Chao Liu et al.   Nature Biomedical Engineering

Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization

(2019) Haiying Zhang et al.   Nature Protocols

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Diagnosis of Invasive Nonfunctional Pituitary Adenomas by Serum Extracellular Vesicles

(2019) Huayi Wang et al.   ANALYTICAL CHEMISTRY

Exosomes

(2019) D. Michiel Pegtel et al.   Annual Review of Biochemistry

Systematic review of targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity

(2019) Johann Mar Gudbergsson et al.   JOURNAL OF CONTROLLED RELEASE

Progress in Microfluidics‐Based Exosome Separation and Detection Technologies for Diagnostic Applications

(2019) Shujing Lin et al.   Small

Personalized detection of circling exosomal PD-L1 based on Fe3O4@TiO2 isolation and SERS immunoassay

(2019) Yuanfeng Pang et al.   BIOSENSORS & BIOELECTRONICS

New Technologies for Analysis of Extracellular Vesicles

(2018) Huilin Shao et al.   CHEMICAL REVIEWS

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

A Magnetic-Based Microfluidic Device for On-Chip Isolation and Detection of Tumor-Derived Exosomes

(2018) Huiying Xu et al.   ANALYTICAL CHEMISTRY

Molecularly Imprinted Polymers

(2018) Joseph J. BelBruno   CHEMICAL REVIEWS

Erratum for the Research Article: “Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy” by X. Gao, N. Ran, X. Dong, B. Zuo, R. Yang, Q. Zhou, H. M. Moulton, Y. Seow, H. Yin

(2018)   Science Translational Medicine

Quantification of Small Extracellular Vesicles by Size Exclusion Chromatography with Fluorescence Detection

(2016) Rui Xu et al.   ANALYTICAL CHEMISTRY

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

(2016) Sivapriya Kailasan Vanaja et al.   CELL

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residual matrix from different separation techniques impacts exosome biological activity

(2016) Lucia Paolini et al.   Scientific Reports

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol

(2015) Mikhail A. Livshits et al.   Scientific Reports

Benchtop isolation and characterization of functional exosomes by sequential filtration

(2014) Mitja L. Heinemann et al.   JOURNAL OF CHROMATOGRAPHY A

Rapid Isolation of Extracellular Vesicles from Cell Culture and Biological Fluids Using a Synthetic Peptide with Specific Affinity for Heat Shock Proteins

(2014) Anirban Ghosh et al.   PLoS One

Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles

(2013) Jonel P. Saludes et al.   Molecular BioSystems

Microwave heating in solid-phase peptide synthesis

(2011) Søren L. Pedersen et al.   CHEMICAL SOCIETY REVIEWS