Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer

(2019) Jiantong Dong et al.   ACS Applied Materials & Interfaces

Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip

(2019) Peng Zhang et al.   Nature Biomedical Engineering

Genome-wide cell-free DNA fragmentation in patients with cancer

(2019) Stephen Cristiano et al.   NATURE

Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

(2019) Reza Rahbarghazi et al.   Cell Communication and Signaling

Extracellular vesicles: a new communication paradigm?

(2019) Graça Raposo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells

(2019) Jiantong Dong et al.   Science Advances

Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications

(2019) Jiantong Dong et al.   ADVANCED MATERIALS

Diagnosis, Staging and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases

(2018) Jorge A. Marrero et al.   HEPATOLOGY

A Novel Multimarker Assay for the Phenotypic Profiling of Circulating Tumor Cells in Hepatocellular Carcinoma

(2018) Colin M. Court et al.   LIVER TRANSPLANTATION

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma

(2018) Xinmei Wang et al.   PLoS One

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma

(2018) S. Manier et al.   Nature Communications

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

(2018) Eduardo Reátegui et al.   Nature Communications

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

(2018) Shu Yi Shen et al.   NATURE

Current and future perspectives of liquid biopsies in genomics-driven oncology

(2018) Ellen Heitzer et al.   NATURE REVIEWS GENETICS

Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

(2018) Mohashin Pathan et al.   NUCLEIC ACIDS RESEARCH

Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma

(2017) Henrike Julich-Haertel et al.   JOURNAL OF HEPATOLOGY

Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

(2017) Rui-hua Xu et al.   NATURE MATERIALS

Integrating liquid biopsies into the management of cancer

(2017) Giulia Siravegna et al.   Nature Reviews Clinical Oncology

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma

(2017) Mark Kalinich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosome separation using microfluidic systems: size-based, immunoaffinity-based and dynamic methodologies

(2017) Fang Yang et al.   Biotechnology Journal

Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes

(2017) Yuan Wan et al.   Nature Biomedical Engineering

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis

(2016) Zheng Zhao et al.   LAB ON A CHIP

Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm

(2016) Benjamin H. Wunsch et al.   Nature Nanotechnology

Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia

(2016) Arnulf Willms et al.   Oncotarget

Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells

(2016) Jie-Fu Chen et al.   Theranostics

Downstaging of hepatocellular cancer before liver transplant: Long-term outcome compared to tumors within Milan criteria

(2015) Francis Y. Yao et al.   HEPATOLOGY

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Characterization of RNA from Exosomes and Other Extracellular Vesicles Isolated by a Novel Spin Column-Based Method

(2015) Daniel Enderle et al.   PLoS One

Biomarkers for the early diagnosis of hepatocellular carcinoma

(2015) Nobuhiro Tsuchiya   WORLD JOURNAL OF GASTROENTEROLOGY

Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol

(2015) Mikhail A. Livshits et al.   Scientific Reports

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

(2014) Shailender Singh Kanwar et al.   LAB ON A CHIP

Molecular analysis of circulating tumour cells—biology and biomarkers

(2014) Matthew G. Krebs et al.   Nature Reviews Clinical Oncology

Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles

(2013) Zongxing Wang et al.   LAB ON A CHIP

Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip

(2013) Weian Sheng et al.   LAB ON A CHIP

Fibrosis-dependent mechanisms of hepatocarcinogenesis

(2012) David Y. Zhang et al.   HEPATOLOGY

Microfluidic filtration system to isolate extracellular vesicles from blood

(2012) Ryan T. Davies et al.   LAB ON A CHIP

Biomarkers for early diagnosis of hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET ONCOLOGY

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

(2011) Shutao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation

(2011) Mark R. Karver et al.   BIOCONJUGATE CHEMISTRY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Three-Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells

(2009) Shutao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Developments in Disulfide Bond Formation

(2008) Dariusz Witt   SYNTHESIS-STUTTGART